Intersectional Stigma, Mental Health, and HIV Risk Among US Gay and Bisexual Men of Color

美国有色人种同性恋和双性恋男性的交叉耻辱、心理健康和艾滋病毒风险

• 批准号: 10228712
• 负责人: Skyler Jackson
• 金额: $ 16.75万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-08-05 至 2024-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10228712
• 关键词: AIDS prevention; Acquired Immunodeficiency Syndrome; Address; Adopted; Area; Attention; Automobile Driving; Award; Behavior; Bisexual; Buffers; Clinical Trials; Collaborations; Color; Communities; Data; Demographic Factors; Diagnosis; Disadvantaged; Doctor of Philosophy; Elements; Epidemic; Epidemiologic Methods; Evidence based intervention; Feedback; Foundational Skills; Future; Gays; Gender; Geographic Factor; Geography; Goals; Grant; Group Therapy; HIV; HIV Infections; HIV diagnosis; HIV risk; Health; Homophobia; Individual; Interdisciplinary Study; Intervention; Intervention Studies; Intervention Trial; Interview; Joints; Knowledge; Latino; Learning; Link; Literature; Manuscripts; Mediator of activation protein; Mental Health; Mentors; Methodology; Minority; Modeling; National Institute of Mental Health; New York; New York City; Phase; Population; Populations at Risk; Preparation; Prevention Research; Process; Production; Prospective cohort study; Protocols documentation; Psyche structure; Public Health; Public Health Schools; Race; Research; Research Methodology; Research Priority; Research Project Grants; Resources; Review Literature; Risk; Risk Behaviors; Sampling; Scientific Advances and Accomplishments; Scientist; Sex Orientation; Sexual Health; Shapes; Social support; Stress; Structural Racism; Structure; Subgroup; System; Tennessee; Testing; Time; Training; Training Activity; Universities; Washington; Writing; career; cohort; coping; data format; demographics; epidemiology study; evidence base; experience; health disparity; health inequalities; high risk; high risk population; improved; insight; interest; intersectionality; longitudinal analysis; men; men who have sex with men; metropolitan; novel; pre-exposure prophylaxis; prevent; preventive intervention; racism; resilience; scale up; sexual risk behavior; skills; social stigma; symposium; theories; therapy development; tool; transmission process

PROJECT SUMMARY/ABSTRACT The burden of HIV is far from equally distributed in the US. Key metrics of the HIV epidemic continue to be predicted by demographic factors (e.g., race, gender, sexual orientation, geography). At the intersection of these determinants is one of the highest-risk groups for HIV infection in the world, and this project's population of interest: Black and Latino gay, bisexual, and other men who have sex with men (GBM) in the US South. Such individuals endure multiple forms of stigma (e.g., racism, homophobia), which elevate stress and erode health. Thus, applying theories of intersectionality and minority stress to epidemiological and intervention research may provide novel insights and tools to support the health of this vulnerable subgroup. The proposed training plan will provide Skyler Jackson, PhD, with the essential knowledge and skills necessary to develop independence and forge a career advancing scientific knowledge concerning intersectional stigma as a determinant of mental and sexual health risk among Black and Latino GBM. The goals of this mentored award are summarized by three distinct training objectives: (1) to gain skills using contemporary epidemiological methods, (2) to learn best practices in qualitative, community-engaged intervention development, and (3) to develop foundational skills in clinical trials methodology. Dr. Jackson will put these aims into practice via three novel, interrelated research projects, in which he will: (1) use longitudinal data from a prospective cohort study to identify mediators and moderators of the association between intersectional stigma and mental/sexual health among GBM of color across distinct US geographies, (2) combine these findings with data from formative research (e.g., 30 interviews with GBM of color and community stakeholders in Middle Tennessee) to modify an existing evidence-based stigma-coping health intervention for GBM—using the 8-phase ADAPT-ITT model—thereby increasing its cultural and geographic relevance to the mental and sexual health of Southern Black and Latino GBM, and (3) pilot this intersectional, culturally-responsive health intervention for young Southern Black and Latino GBM (n = 30; across two sequential cohorts) in collaboration with a community partner in Middle Tennessee. To develop his independence as a scientist, Dr. Jackson will be mentored by John Pachankis, PhD (Yale University), with support from additional co-mentors: Lisa Bowleg, PhD (George Washington University), Dustin Duncan, ScD (New York University), and Mark Hatzenbuehler, PhD (Columbia University). Where knowledge gaps remain, Dr. Jackson will engage in carefully selected training activities—e.g., grant writing, coursework, conferences, and manuscript preparation. Much of this training will be made possible by institutional support available through Dr. Jackson's joint affiliation with the Yale Center for Interdisciplinary Research on AIDS, Yale School of Public Health (YSPH), and YSPH Esteem Research Lab in New York City. Dr. Jackson's K01 training plan is optimized to address his training gaps and prepare him for a productive career as an independent scientist.

项目总结/摘要 艾滋病毒的负担在美国远远没有平均分布。艾滋病毒流行的关键指标仍然是 由人口统计因素预测（例如，种族、性别、性取向、地域）。交叉口 这些决定因素是世界上艾滋病毒感染的最高风险群体之一， 感兴趣的人群：黑人和拉丁美洲同性恋者，双性恋者和其他与男性发生性关系的男性（GBM） 美国南部。这些人忍受着多种形式的耻辱（例如，种族主义，同性恋恐惧症），这会增加压力 侵蚀健康因此，将交叉性和少数群体压力理论应用于流行病学和 干预研究可能提供新的见解和工具，以支持这一弱势群体的健康。 拟议的培训计划将为Skyler杰克逊博士提供必要的知识和技能 必须发展独立性，并建立一个职业生涯，推进科学知识， 交叉污名作为黑人和拉丁裔GBM精神和性健康风险决定因素的 该指导奖的目标概括为三个不同的培训目标：（1）获得使用 现代流行病学方法，（2）学习定性，社区参与的最佳做法 干预措施的发展，（3）发展临床试验方法学的基本技能。杰克逊医生会 通过三个新颖的、相互关联的研究项目将这些目标付诸实践，在这些项目中，他将：（1）使用 一项前瞻性队列研究的纵向数据，以确定该关联的中介者和调节者 在美国不同地区的有色人种GBM中，交叉污名与心理/性健康之间的关系， (2)联合收割机将这些发现与形成性研究的数据相结合（例如，30次采访GBM的颜色和 田纳西州中部的社区利益相关者）修改现有的基于证据的污名应对健康 GBM的干预-使用8相ADAPT-ITT模型-从而增加其文化和地理 与南方黑人和拉丁裔GBM的心理和性健康的相关性，以及（3）试点这种交叉， 对年轻的南方黑人和拉丁裔GBM进行文化响应的健康干预（n = 30;在两个 连续队列）与田纳西州中部的社区合作伙伴合作。发展他 作为一名独立的科学家，杰克逊博士将由约翰Pachankis，博士（耶鲁大学）， 其他共同导师的支持：丽莎鲍莱格，博士（乔治华盛顿大学），达斯汀邓肯，科学博士 (New约克大学）和Mark Hatzenbuehler博士（哥伦比亚大学）。在知识差距仍然存在的地方， 博士杰克逊将参与精心挑选的培训活动，例如，补助金写作，课程，会议， 和手稿准备。这种培训的大部分将通过现有的机构支助来实现 通过杰克逊博士与耶鲁大学艾滋病跨学科研究中心的联合关系， 公共卫生（YSPH）和YSPH尊重研究实验室在纽约市。杰克逊博士的K 01训练计划是 优化，以解决他的培训差距，并准备他作为一个独立的科学家富有成效的职业生涯。