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Mentorship in precision pain medicine via EPPIC-NET

通过 EPPIC-NET 进行精准疼痛医学指导

基本信息

批准号：
10426787
负责人：
ROBERT R EDWARDS
金额：
$ 31.89万
依托单位：
BRIGHAM AND WOMEN'S HOSPITAL
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-09-30 至 2024-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10426787
关键词：
Acute Pain Address Adult Area Biological Biological Markers Childhood Clinical Clinical Data Clinical Investigator Clinical Research Clinical Trials Collaborations Conceptions Ensure Faculty Foundations Funding Generations Goals Individual Differences Industry Information Technology Infrastructure Leadership Logistics Medicine Mentors Mentorship Methodology Neurobiology Neurosciences Pain Pain Research Pain management Participant Patients Phase Phase II Clinical Trials Phenotype Population Practice Management Principal Investigator Research Research Personnel Research Project Grants Resources Scientist Sensory Site Societies Testing Time Training Training Programs Training and Education Translating United States National Institutes of Health Work biomarker validation biopsychosocial career chronic pain clinical investigation clinical pain data management design experience individual patient innovation interest multidisciplinary non-opioid analgesic novel patient oriented research patient population skills tool treatment response validation studies

项目摘要

Abstract The Early Phase Pain Investigation Clinical Network (EPPIC-Net) is designed to rapidly and efficiently translate advances in the neurobiology of pain into treatments for people with chronic and acute pain, conditions associated with a significant burden to both patients and society. Dr. Edwards is one of the Principal Investigators of EPPIC-Net’s Clinical Coordinating Center (CCC); the primary goal of the CCC for EPPIC-Net is to promote and facilitate, from initial conception through final analysis, clinical trials in adult and pediatric populations with acute or chronic pain by providing efficient methodological, organizational and logistical support. One of the CCC’s Specific Aims is to expand the pool of experienced clinical Investigators and research staff to be participants and leaders of multicenter clinical research trials by providing education, training, resources and professional mentorship. This K24 would allow Dr. Edwards to increase the amount of time he spends mentoring junior pain scientists. Much of this mentoring will involve work on precision pain medicine, including biomarker validation studies, and deep phenotyping of patient populations to understand the biologic basis of a specific pain condition and its response to treatment. Collectively, there is an urgent need for more research to establish best practices in clinical pain management, and a limited workforce pipeline of clinical pain researchers to meet NIH’s long-term goals of providing effective non-opioid options for the treatment of pain conditions. Increasing the supply and availability of mentors in the field with the goal of mentoring a new generation of diverse and highly skilled clinical pain researchers is a critically-important goal addressed by this K24. This project would efficiently leverage current HEAL funding (for the EPPIC-Net CCC) to encourage an interest in the field of clinical pain management, generate innovative research projects, and increase the number of clinical researchers, especially research from diverse background, trained in high-quality clinical pain research.

摘要