Optimizing SARS-CoV-2 Testing and Promotores Interventions to Serve Latinx Communities

优化 SARS-CoV-2 检测和 Promotores 干预措施以服务拉丁裔社区

• 批准号: 10414385
• 负责人: WILLIAM A CRESKO
• 金额: $ 110.46万
• 依托单位: UNIVERSITY OF OREGON
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-15 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10414385
• 关键词: 2019-nCoV; Address; American; Behavior Therapy; CLIA certified; COVID-19; COVID-19 diagnostic; COVID-19 health disparity; COVID-19 pandemic; COVID-19 testing; COVID-19 vaccination; Censuses; Centers for Disease Control and Prevention (U.S.); Communities; Community Outreach; County; Data; Data Analyses; Diagnostic tests; Education; Equipment and Supplies; Ethnic Origin; Event; Feedback; Future; Genomics; Goals; Grant; Guidelines; Health; Health Promotion; Health behavior; Hispanics; Home; Hospitals; Immigrant; Immigration; Individual; Intervention; Knowledge; Laboratories; Latinx; Lead; Location; Masks; Methods; Mexican; Modeling; Molecular; Morbidity - disease rate; Oregon; Outcome; Phase; Population; Prevention; Protocols documentation; Public Health; RADx Underserved Populations; Race; Research Methodology; Research Personnel; Research Project Grants; Science; Scientific Evaluation; Scientist; Services; Site; Structure; System; Test Result; Testing; Time; Travel; Underserved Population; United States; Vaccinated; Vaccination; Variant; Virus; Visit; Work; authority; base; burden of illness; community based participatory research; community organizations; community partnership; density; effectiveness testing; experience; health disparity; implementation fidelity; improved; infection rate; innovation; insight; interest; mortality; outreach; pandemic disease; phase 1 testing; phase 2 study; predictive test; programs; protective behavior; scale up; social health determinants; sustainability framework; testing access; testing uptake; transmission process; vaccine acceptance; vaccine access; vaccine hesitancy

PROJECT SUMMARY The global SARS-CoV-2 pandemic is the worst health crisis the United States and world have faced in a century. Although this highly contagious virus has infected tens of millions of Americans already, the pandemic is far from over, and the disease burdens continue to be disproportionately born by historically underserved populations such as Latinx communities. Nationally, Latinx people with COVID-19 are hospitalized at four times the rate of Whites and have much higher rates of morbidity and mortality. This disparity is notable in Oregon, where the 13% of our population that is Latinx represents approximately 24% of COVID-19 cases. Yet, vaccination rates for Latinx remain below the state average. Thus, an urgent need exists to reach Oregon’s Latinx community with public health and prevention messages that emphasize the value of continued COVID-19 testing and that address vaccine hesitancy. This project will build upon our successful RADx-UP Phase I culturally-tailored community outreach and testing program through the implementation of Phase II goals of increasing the reach and uptake of testing and decreasing vaccine hesitancy in Latinx individuals in Oregon. The project will maintain and expand a world-class team of prevention scientists, public health experts, Latinx researchers, community partners, and biologists who have been working together to conduct SARS-CoV-2 diagnostic testing since March 2020. This team established a CLIA-certified laboratory and honed molecular testing protocols, procured millions of dollars of diagnostic testing equipment and supplies, and partnered with county public health offices and hospitals throughout the state to conduct testing. The team has been engaged in comprehensive community partnerships using community-based participatory research methods in Phase I to deliver a culturally-tailored intervention that shows preliminary efficacy in increasing testing among Latinx individuals. Building on the lessons learned in the first 6 months of our Phase I RADX-UP testing, we will refocus our existing testing program to broaden our reach by partnering with state and community organizations offering other services to Latinx communities across Oregon. With continued support from the Latinx Community and Scientific Advisory Board, the project will refocus to support the testing of 100 individuals each month across the state of Oregon, focusing specifically on locating testing events at venues that serve Latinx individuals (e.g., mobile Mexican Consulate events across the state). The previously launched health intervention (Promotores de Salud) will also be refocused to promote the benefits of continued testing and vaccination uptake, and barriers to these important health behaviors will be evaluated. Over time, this project will continue to help communities institutionalize optimal local testing frameworks that are sustainable. The resulting testing and structures and systems will be poised for future scale-up to other vulnerable communities and/or for other public health purposes. This project is expected to lead to a major reduction in COVID-19 health disparities in underserved populations.

项目摘要 全球SARS-CoV-2大流行是美国和世界面临的最严重的健康危机， 世纪。尽管这种高度传染性的病毒已经感染了数千万美国人， 疾病负担继续不成比例地由历史上得不到充分服务的人承担 例如拉丁裔社区。在全国范围内，患有COVID-19的拉丁裔人在四岁时住院 是白人的两倍，发病率和死亡率也高得多。这种差异在以下方面值得注意： 在俄勒冈州，拉丁裔人口占总人口的13%，约占COVID-19病例的24%。 然而，拉丁裔的疫苗接种率仍然低于国家平均水平。因此，迫切需要 俄勒冈州的拉丁裔社区与公共卫生和预防信息，强调继续的价值， COVID-19检测和解决疫苗犹豫问题。该项目将建立在我们成功的RADx-UP 第一阶段通过实施第二阶段， 目标是增加测试的覆盖面和吸收率，减少拉丁裔个体的疫苗犹豫， 俄勒冈州。该项目将维持和扩大一个世界级的预防科学家，公共卫生 专家、拉丁美洲研究人员、社区合作伙伴和生物学家，他们一直在共同努力， 自2020年3月起进行SARS-CoV-2诊断检测。该团队建立了CLIA认证的实验室， 完善了分子检测方案，采购了数百万美元的诊断检测设备和用品， 并与全州的县公共卫生办公室和医院合作进行检测。球队 利用基于社区的参与性研究， 第一阶段的方法提供文化定制的干预措施，显示出增加的初步功效 在拉丁人中进行测试。基于我们第一阶段RADX-UP的前6个月所吸取的经验教训 测试，我们将重新调整我们现有的测试计划，以扩大我们的范围，与国家和 社区组织，为俄勒冈州的拉丁裔社区提供其他服务。的持续支持下 从拉丁美洲社区和科学咨询委员会，该项目将重新调整重点，以支持测试100 每个月在俄勒冈州的个人，特别侧重于在场地定位测试事件 为拉丁裔人服务的公司（例如，全国各地的移动的墨西哥领事馆活动）。先前 启动的健康干预（Promotores de Salud）也将重新调整重点，以促进持续健康的益处。 将评估这些重要健康行为的检测和疫苗接种率以及障碍。随着时间的推移， 该项目将继续帮助社区将最佳的本地测试框架制度化， 可持续由此产生的测试和结构和系统将准备在未来扩大到其他 弱势群体和/或其他公共卫生目的。该项目预计将导致一个重大的 减少服务不足人群的COVID-19健康差距。