The WashU-UCSC-EBI Human Genome Reference Center."

项目总结(项目2补编) 基于WASH U-UCSC-EBI的人类基因组参考中心(HGRC)的目标是维持和 更新由人类基因组参考计划(HGRP)编制的新的人类基因组参考 把它提供给科学界。HGRP推广和教育中心(HGRP-OE)的目标是 与整个科学界和医学界进行沟通，传播数据、资源、工具、 礼仪和教育材料。在本增刊中，我们计划显著扩大我们的外展范围和 教育努力在全球基因组学与健康联盟(GA4GH)之间建立战略伙伴关系 和人类盘根组项目(包括人类盘根组参考联盟和国际 伙伴关系)。我们将建立、发展和协调全球Pangenome参考社区，以帮助 确保(A)该社区的组织和通信需求；(B)网站开发和 维护；(C)与HPRC协调中心和GA4GH社区整合。如果成功 实施后，我们提议的扩展将极大地提高社区对新人类基因组的认识 引用及其用法，从而最大限度地提高其用途、价值和意义；并将扩大其使用和 应用工具，促进安全和负责任的数据共享，并进一步促进全球和国家的参与 基因组学和精确健康方面的项目。

PROJECT SUMMARY (PROJECT 2 SUPPLEMENT) The goal of the WashU-UCSC-EBI based Human Genome Reference Center (HGRC) is to maintain and update the new human genome reference produced by the Human Genome Reference Program (HGRP) and to provide it to the scientific community. The goal of the HGRP Outreach and Education Center (HGRP-OE) is to communication with the entire scientific and medical communities and disseminate data, resources, tools, protocols, and educational materials. In this supplement, we plan to significantly expand our outreach and education effort to form a strategic partnership between the Global Alliance for Genomics and Health (GA4GH) and the Human Pangenome Project (including the Human Pangenome Reference Consortium and international partnerships). We will establish, develop and coordinate the Global Pangenome Reference Community to assist in ensuring the (a) organization and communications needs for this community; (b) website development and maintenance; (c) integration with HPRC Coordination Center and GA4GH Community. If successfully implemented, our proposed expansion will greatly increase community awareness of the new human genome reference and its usage, and thus maximize its use, value, and significance; and will expand the use and application of tools to facilitate secure and responsible data-sharing, and further engage global and national projects in genomics and precision health.