Center for Biomedical and Brain Imaging (CBBI)

生物医学和脑成像中心 (CBBI)

• 批准号: 10425001
• 负责人: KEITH ALLAN SCHNEIDER
• 金额: $ 28.92万
• 依托单位: DELAWARE STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-01 至 2027-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10425001
• 关键词: Animal Model; Animals; Applications Grants; Area; Award; Behavior; Behavioral; Bioinformatics; Biological; Biomedical Engineering; Brain; Brain imaging; Centers of Research Excellence; Cognition; Collaborations; Communities; Consult; Consultations; Data; Data Analyses; Delaware; Disease; Environment; Evaluation; Experimental Designs; Exploratory/Developmental Grant for Diagnostic Cancer Imaging; Faculty; Feeling; Foundations; Funding; Genetic; Goals; Grain; Grant; Human; Human Resources; Imaging technology; Injury; Investigation; Investments; Longevity; Magnetic Resonance Imaging; Maps; Memory; Methods; Molecular; Nervous System Physiology; Neurosciences; Neurosciences Research; Pathologic; Phase; Positioning Attribute; Productivity; Psychologist; Publications; Research; Research Personnel; Research Project Grants; Research Support; Resolution; Resources; Rodent Model; Signal Transduction; Structure; Techniques; Technology; Thinking; Time; United States National Institutes of Health; Universities; base; biomedical imaging; career; data acquisition; experience; human data; human imaging; human model; human subject; improved; innovation; insight; medical schools; multidisciplinary; neuroimaging; non-invasive imaging; programs; public health relevance

Center for Biomedical and Brain Imaging (CBBI) Summary The major objective of the Center for Biomedical and Brain Imaging (CBBI) Core is to provide support and educational opportunities to neuroscientists in Delaware who are investigating structure-function-behavior relationships in the brain, and help them develop new neuroimaging approaches that will advance their research and careers. By combining animal and human neuroimaging, our CBBI Core serves a second objective of bringing together biologists, psychologists, biomedical engineers and others who image the human brain, with molecular, cellular and behavioral neuroscientists who use animal models, to catalyze collaborations focusing on multi-scale investigations of functional activity in the brain. The University of Delaware (UD) has made a significant investment into building capabilities for human and animal neuroimaging- purchasing a 3T MRI scanner with the capability to map human brain structure and function, and with partial support from our Phase II COBRE, a 9.4T, small bore scanner for high resolution mapping of the structure and function of brains in rodent models. Our CBBI core will support investigators utilizing non-invasive neuroimaging techniques by providing access to collaborators and consulting expertise to help develop innovative projects that can form the basis for competitive, interdisciplinary grant applications. Our objective for this aim is to increase the number of neuroscience investigators at DSU, UD and across the state who have research project grant funding from NIH. Currently our CBBI core has contributed to active R01 awards to six faculty and R21 awards for 8 faculty. Our objective is to double those numbers to 12 faculty with R01 awards and 16 with R21 awards. Our Phase III COBRE award will support a program of Core Access Awards to allow Delaware researchers to collect pilot neuroimaging data to support publications and grant applications. Currently there are 35 faculty PIs using the CBBI Core, and we expect that our Core Access Award program will grow that number 50% to over 50 by the end of our Phase III award. The unifying focus of the Delaware Center for Neuroscience Research is investigating how the dynamic structures of the brain are changed over the lifespan by experiences, the environment and genetics. Our Biomedical and Brain Imaging Core provides crucial support for neuroscientists affiliated with the Delaware Center for Neuroscience Research to reach their full scientific and professional potential - including attaining grant support for their research. It also creates an environment that helps attract outstanding neuroscience researchers to fill new positions, at both DSU and UD, while advancing the research of a broader community of neuroscientists already in Delaware

生物医学和脑成像中心(CBBI) 摘要 生物医学和脑成像中心的主要目标 核心是为特拉华州的神经科学家提供支持和教育机会 他们正在研究大脑中的结构-功能-行为关系，并帮助 他们开发了新的神经成像方法，这将促进他们的研究和职业生涯。 通过结合动物和人类的神经成像，我们的CBBI核心服务于第二个目标，即将 生物学家、心理学家、生物医学工程师和其他为人类大脑成像的人，用分子、细胞和 行为神经学家使用动物模型，以促进专注于多尺度研究的合作 大脑的功能活动。特拉华大学(UD)在建筑方面投入了大量资金 人类和动物的神经成像能力-购买一台能够绘制人脑地图的3T磁共振扫描仪 结构和功能，并在我们的第二阶段Cobre的部分支持下，9.4T，小口径扫描器 啮齿动物模型中大脑结构和功能的分辨率图谱。 我们的CBBI核心将为使用非侵入性神经成像技术的调查人员提供 协作者和咨询专业知识，以帮助开发创新项目，这些项目可以构成具有竞争力的、 跨学科拨款申请。我们的目标是增加神经科学研究人员的数量 在密歇根州立大学、密歇根州立大学和全州都有来自NIH的研究项目拨款。目前我们的CBBI核心有 为6名教师颁发了有效的R01奖，为8名教师颁发了R21奖。我们的目标是使这一数字翻一番 授予12名教职员工R01奖和16名R21奖。我们的第三阶段Cobre奖将支持Core的一个计划 Access Awards允许特拉华州的研究人员收集试点神经成像数据以支持出版物和授予 申请。目前有35名教师绩效指标使用CBBI核心，我们预计我们的核心访问奖 到我们的第三阶段奖项结束时，该计划的人数将增长50%，超过50人。 特拉华州神经科学研究中心的统一焦点是调查动态 在人的一生中，大脑的结构会因经历、环境和遗传而发生变化。我们的生物医学 和脑成像核心为附属于特拉华中心的神经科学家提供关键支持 神经科学研究充分发挥其科学和专业潜力-包括获得拨款支持 他们的研究。它还创造了一个环境，有助于吸引优秀的神经科学研究人员填补新的 职位，同时推动更广泛的神经科学家社区的研究已经 特拉华州