Center for Biomedical and Brain Imaging (CBBI)

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Center for Biomedical and Brain Imaging (CBBI) Summary The major objective of the Center for Biomedical and Brain Imaging (CBBI) Core is to provide support and educational opportunities to neuroscientists in Delaware who are investigating structure-function-behavior relationships in the brain, and help them develop new neuroimaging approaches that will advance their research and careers. By combining animal and human neuroimaging, our CBBI Core serves a second objective of bringing together biologists, psychologists, biomedical engineers and others who image the human brain, with molecular, cellular and behavioral neuroscientists who use animal models, to catalyze collaborations focusing on multi-scale investigations of functional activity in the brain. The University of Delaware (UD) has made a significant investment into building capabilities for human and animal neuroimaging- purchasing a 3T MRI scanner with the capability to map human brain structure and function, and with partial support from our Phase II COBRE, a 9.4T, small bore scanner for high resolution mapping of the structure and function of brains in rodent models. Our CBBI core will support investigators utilizing non-invasive neuroimaging techniques by providing access to collaborators and consulting expertise to help develop innovative projects that can form the basis for competitive, interdisciplinary grant applications. Our objective for this aim is to increase the number of neuroscience investigators at DSU, UD and across the state who have research project grant funding from NIH. Currently our CBBI core has contributed to active R01 awards to six faculty and R21 awards for 8 faculty. Our objective is to double those numbers to 12 faculty with R01 awards and 16 with R21 awards. Our Phase III COBRE award will support a program of Core Access Awards to allow Delaware researchers to collect pilot neuroimaging data to support publications and grant applications. Currently there are 35 faculty PIs using the CBBI Core, and we expect that our Core Access Award program will grow that number 50% to over 50 by the end of our Phase III award. The unifying focus of the Delaware Center for Neuroscience Research is investigating how the dynamic structures of the brain are changed over the lifespan by experiences, the environment and genetics. Our Biomedical and Brain Imaging Core provides crucial support for neuroscientists affiliated with the Delaware Center for Neuroscience Research to reach their full scientific and professional potential - including attaining grant support for their research. It also creates an environment that helps attract outstanding neuroscience researchers to fill new positions, at both DSU and UD, while advancing the research of a broader community of neuroscientists already in Delaware