Interdisciplinary Training in Biobehavioral Pain Research

生物行为疼痛研究的跨学科培训

• 批准号: 10443742
• 负责人: Xinzhong Dong
• 金额: $ 33.6万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-30 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10443742
• 关键词: Pain Research; Training; biobehavior

Pain is one of the most common and costly symptoms in our society. Advances in pain treatment have been disappointing, especially for chronic pain, which is poorly understood and the leading cause of disability worldwide. Given the tremendous cost and impact of pain, it is important to develop an interdisciplinary research workforce capable of leading innovative studies to unravel the causes of persistent pain and discover better pain relief strategies. Our goal is to prepare the next generation of pain researchers to lead this effort. As such, we seek to renew and expand our postdoctoral Interdisciplinary Training Program in Biobehavioral Pain Research at the Johns Hopkins University from four to six positions. Pain is a highly complex phenomenon that involves, genetic, molecular, neurophysiologic, cognitive-emotional, and sociocultural determinants. The treatment of pain remains inadequate in almost every clinical situation and consequently necessitates institutions create specialized, interdisciplinary training in pain research to address the tremendous challenge of developing, evaluating, disseminating, and integrating effective pain treatments into clinical care. As such, the Institute of Medicine’s ‘Relieving Pain in America’ report notes the importance and need for more interdisciplinary pain training programs. Our 26 program faculty cuts across 10 departments in the Schools of Medicine, Nursing, Public Health, and Engineering. The overarching goal of the proposed postdoctoral program is to prepare the next generation of innovative research leaders to work cooperatively within an interdisciplinary team to address the complex problem of pain. This proposal emphasizes the neuroscience of pain throughout training. Each faculty mentor is an actively funded scientist, engaged in the education of new investigators, and committed to interdisciplinary collaboration. The two-year program incorporates coursework, seminars and mentored research experiences in at least two scientific domains that are synthesized by: 1) an integrated research project, 2) an extramural grant application, and 3) the writing and publishing of papers. The training objectives are to: 1) develop an enhanced foundation in the neuroscience of pain; 2) engender a broad conceptualization of pain that includes, but is not limited to, neurobiologic, cognitive, emotional, behavioral, and social processes; 3) develop skills for communicating, networking and collaborating with scientists in other disciplines; and 4) design and conduct an integrative pain research project. Each fellow is to be collaboratively mentored by two Core faculty with distinct domains of pain research expertise in either: 1) basic neuroscience, 2) clinical research or 3) behavioral or social science. Fellows take courses in experimental design, statistics, quantitative methods and the responsible conduct of research, which are reinforced throughout several pain-related content and career development seminars. Our goal is to prepare the next generation of pain scientists to lead interdisciplinary research teams that will innovatively address the problem of pain.

疼痛是我们社会中最常见和代价最高的症状之一。疼痛治疗的进展令人失望，特别是对慢性疼痛，人们对此知之甚少，是全世界导致残疾的主要原因。鉴于疼痛的巨大成本和影响，重要的是培养一支跨学科的研究队伍，能够领导创新研究，揭示持续性疼痛的原因，并发现更好的疼痛缓解策略。我们的目标是准备好下一代疼痛研究人员来领导这项工作。因此，我们寻求更新和扩大我们在约翰霍普金斯大学生物行为疼痛研究的博士后跨学科培训计划，从四个职位增加到六个职位。疼痛是一种高度复杂的现象，涉及遗传、分子、神经生理学、认知-情绪和社会文化决定因素。疼痛的治疗在几乎所有的临床情况下仍然是不够的，因此需要机构在疼痛研究方面建立专门的、跨学科的培训，以应对开发、评估、传播有效的疼痛治疗并将其整合到临床护理中的巨大挑战。因此，美国医学研究所的《缓解美国疼痛》报告指出了更多跨学科疼痛培训计划的重要性和必要性。我们的26名项目教员分布在医学院、护理学院、公共卫生学院和工程学院的10个系。拟议的博士后计划的首要目标是培养下一代创新的研究领导者，以便在跨学科团队中合作解决复杂的疼痛问题。这项建议强调在整个训练过程中疼痛的神经科学。每一位教师导师都是一位积极资助的科学家，致力于新研究人员的教育，并致力于跨学科合作。这项为期两年的计划包括至少两个科学领域的课程作业、研讨会和指导研究经验，这两个领域的综合包括：1)综合研究项目，2)外部拨款申请，3)论文写作和发表。培训目标是：1)加强疼痛神经科学的基础；2)形成对疼痛的广泛概念化，包括但不限于神经生物学、认知、情感、行为和社会过程；3)发展沟通、网络和与其他学科科学家合作的技能；以及4)设计和实施综合疼痛研究项目。每名研究员将由两名核心教员合作指导，他们在以下两个领域拥有不同的疼痛研究专业知识：1)基础神经科学，2)临床研究，或3)行为或社会科学。研究员们学习实验设计、统计学、量化方法和负责任的研究方法等课程，这些课程在几个与疼痛相关的内容和职业发展研讨会中得到加强。我们的目标是培养下一代疼痛科学家，领导跨学科的研究团队，创新地解决疼痛问题。