Assessing a Novel Virtual Environment that Primes Individuals Living with AD/ADRD to Accomplish Activities of Daily Living.

评估一种新颖的虚拟环境，该环境可以帮助 AD/ADRD 患者完成日常生活活动。

• 批准号: 10325754
• 负责人: Mandy Salomon
• 金额: $ 49.13万
• 依托单位: MENTIA DTX, INC.
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-30 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10325754
• 关键词: 3-Dimensional; Accounting; Activities of Daily Living; Aggressive behavior; Alzheimer' s disease related dementia; Attention; Caregiver Burden; Caregivers; Caring; Communication; Communities; Computer software; Confusion; Custom; Data; Dementia; Dependence; Development; Direct Costs; Disease; Disorientation; Ecological momentary assessment; Ecosystem; Elements; Emotions; Environment; Evaluation; Eye; Feasibility Studies; Fostering; Goals; Health; Health Care Costs; Home; Independent Living; Individual; Institutes; Intelligence; Labor Forces; Legal patent; Measurement; Measures; Medicare; Medicine; Modality; Morbidity - disease rate; Occupations; Participant; Pathway interactions; Performance; Personal Satisfaction; Personhood; Persons; Phase; Pilot Projects; Population; Preparation; Prevalence; Process; Property; Protocols documentation; Psychosocial Assessment and Care; Public Policy; Quality of life; Randomized; Resources; Risk; Services; Speech; Stimulus; Stress; Surveys; System; Tablets; Technology; Testing; Time; Toothbrushing; Training; Voice; Work; acceptability and feasibility; aging population; base; behavioral health; care recipients; care systems; control trial; cost; cost effective; dementia care; design; digital; digital health; health economics; improved; member; memory care; mortality; new technology; novel; operation; pressure; primary outcome; research and development; satisfaction; secondary outcome; self esteem; socioeconomics; stressor; success; virtual; virtual environment; virtual world

ABSTRACT The prevalence of Alzheimer’s disease and related dementias (ADRD) is growing in an increasingly aging population. Care challenges to maintain health and quality life for persons living with dementias (PLWD) has also created a parallel health problem from the effects of persistent caregiver job stress, resulting in staff turnover expense and care operations risk in a scarce job pool. Improving the rate of completion of Activities of Daily Living (ADL) has a known positive impact on the quality of life, health, and healthcare costs yet consistently completing ADLs, and without stress, for PLWD and their carers remains a challenge. We hypothesize that undertaking virtual ADL activities will positively impact actual ADL activities, resulting in easier and more efficient ADL completion and therefore decrease caregiver stress, and, with dignity, improve the health and quality of life for PLWD. Mentia is an early-stage digital health company that has developed DevaWorld™, a novel technology platform focused on improving behavioral health for people impacted by ADRD. DevaWorld, as an assistive software application technology, is unique in that it considers care as a partnership, with the care recipient being an active participant, even though their dementia may be severe. The cost-effective platform consists of a media-rich 3D virtual home with interactive items and activities that can be used to build communication within the care dyad and foster a sense of agency and identity. The goal of the proposed work is to demonstrate tolerability and acceptability of DevaWorld, and assess the impact of virtual ADL activity on both partners of the dyad, paying special attention to how consistent performance of ADLs inside DevaWorld by PLWD reduces caregiver stress. In this work, two specific aims are proposed: Aim 1: Expand DevaWorld to include environments and activities most often cited as challenges in regard to ADLs. We hypothesize that players can be prepared to perform ADLs via virtual world interactions. This aim entails the design of settings, activities, and interactive avatar actions within DevaWorld intended to prepare the player in selected ADLs. Aim 2: Demonstrate feasibility and acceptability of DevaWorld in a feasibility study. Qualitative measurements using ecological momentary assessments (EMAs) and quantitative measurements of independence through activities of daily living (ADL) scale assessments will be assessed while 16 players with ADRD undertake virtual and real-world ADLs (AIM 1) (single group study). The primary outcome of this aim is tolerability and acceptability of DevaWorld assessed by caregiver surveys and EMAs. The secondary outcome is feasibility and efficacy of preparing ADLs using DevaWorld assessed by AMMODE, validated caregiver surveys of stressors and ADL scale assessment scores.

摘要 阿尔茨海默病和相关痴呆（ADRD）的患病率在日益老龄化的人口中不断增长， 人口为痴呆症患者（PLWD）维持健康和高质量生活的护理挑战 由于持续的护理人员工作压力的影响，也造成了平行的健康问题，导致工作人员更替 在稀缺的工作岗位上承担费用和护理操作风险。 提高日常生活活动（ADL）的完成率对提高学生的生活质量有着积极的影响。 生活、健康和医疗保健费用，但持续完成ADL，PLWD及其护理人员没有压力 仍然是一个挑战。我们假设进行虚拟ADL活动将对实际的 ADL活动，导致更容易和更有效的ADL完成，因此减少照顾者 消除压力，并有尊严地改善PLWD的健康和生活质量。 Mentia是一家处于早期阶段的数字健康公司，它开发了一种新的技术平台DevaWorld™ 专注于改善受ADRD影响的人的行为健康。DevaWorld作为一个辅助软件 应用技术，是独一无二的，因为它认为照顾作为一种伙伴关系，与照顾接受者是一个积极的 参与者，即使他们的痴呆症可能很严重。高性价比的平台包括多媒体3D 具有交互式项目和活动的虚拟家庭，可用于在护理二人组内建立通信 并培养一种能动性和认同感。拟议工作的目标是证明耐受性， DevaWorld的可接受性，并评估虚拟ADL活动对二分体双方的影响， 特别注意PLWD在DevaWorld内部ADL的一致性能如何降低 照顾者压力 在这项工作中，提出了两个具体目标： 目标1：扩展DevaWorld，以包括最常被视为挑战的环境和活动， 关于ADLs我们假设，玩家可以准备通过虚拟世界的互动来执行ADL。 这个目标需要在DevaWorld中设计设置，活动和交互式化身动作， 让玩家在选定的ADL中做好准备。 目标2：在可行性研究中证明DevaWorld的可行性和可接受性。定性 使用生态瞬时评估（EMAs）和定量测量 通过日常生活活动（ADL）量表评估的独立性将被评估，而16名球员， ADRD进行虚拟和真实世界ADL（AIM 1）（单组研究）。这一目标的主要成果是 通过护理人员调查和EMA评估DevaWorld的耐受性和可接受性。次要结局 使用DevaWorld准备ADL的可行性和有效性是否由AMMODE（经验证的护理人员）评估 压力源和ADL量表评估评分的调查。