Development of a Digital Cognitive Screening Test to detect Mild Cognitive Impairment and Dementia in Clinical Settings.

项目摘要 阿尔茨海默氏症和相关的痴呆症是我们老龄化人口中日益严重的健康问题。 对认知功能的评估以早期发现，对于识别可能 从轻度痴呆症的现有对症药物治疗中受益以及未来 正在积极开发并在临床研究中进行测试的疾病修改疗法 审判。目前的认知筛查工具非常耗时，并且没有常规使用或记录在 初级保健设置繁忙。因此，我们需要易于使用的工具，例如患者自我管理 措施，对初级保健环境中的个人进行筛查，以指导咨询、转诊和干预。 拟议的STTR第一阶段项目旨在开发和测试一种创新的数字认知筛选 RIMCAT(罗德岛移动认知评估工具)用于识别轻度认知 老年人的损害和痴呆症。RIMCAT由10个组件组成，专为 在受监督的环境中进行自我管理，如初级保健实践，并提供 认知友好的界面，允许语音输入、键盘打字和易于理解的说明。 该STTR项目的目标是通过一个 心理测量学研究。该项目还包括开发一个数字健康框架，以支持 MCI/痴呆筛查的工作流程。这项工作将建立RIMCAT在较老的人群中的可用性 可以在数字平台上接受筛查评估的成年人，无论他们的能力如何 使用现代移动技术。

Project Summary Alzheimer’s disease and related dementias are a growing health problem in our aging population. Assessment of cognitive functioning for early detection is critical to identify individuals who might benefit from treatment with the available symptomatic medications for mild dementia as well as future disease-modifying therapies that are actively under development and being tested in clinical research trials. Current cognitive screening tools are time-consuming and not routinely used or documented in busy primary care settings. As a result, we need easily accessible tools, such as patient self-administered measures, to screen individuals in primary care settings to guide counseling, referrals, and interventions. The proposed STTR Phase I project aims to develop and test an innovative digital cognitive screening instrument, RIMCAT (Rhode Island Mobile Cognitive Assessment Tool) to identify mild cognitive impairment and dementia in older adults. RIMCAT consists of 10 components and was designed for self-administration in supervised settings such as primary care practices and provides a cognitive-friendly interface allowing voice inputs, keyboard typing, and easy-to-understand instructions. The goal of this STTR project is to examine the initial reliability and validity of RIMCAT through a psychometric study. The project also includes the development of a digital health framework to support the workflow of MCI/dementia screening. This work will establish the usability of RIMCAT among older adults who could undergo the screening assessment on a digital platform, regardless of their ability to use modern mobile technologies.