Emory Training Program in Translational Research to End the HIV Epidemic

工程摘要 在这份题为“埃默里终止艾滋病毒流行转化研究培训方案”的申请中， 我们提出了一个新的T32培训计划，重点是位于震中的转化艾滋病毒科学， 美国艾滋病毒在美国南部的流行，在亚特兰大埃默里大学，佐治亚州。我们的培训计划将提供2 为5名博士后研究员提供了多年的支持，并为2名博士预科生提供了暑期实习机会， 代表少数民族（URM）学生通过实践经验进行尖端的艾滋病毒研究， 正式的教学法，并教育学员在更广泛的背景下，艾滋病毒研究的翻译 连续体我们的培训计划将充分结合并利用重要的艾滋病毒研究 埃默里艾滋病研究中心（CFAR）的投资组合，并跨越正在进行的艾滋病毒研究的范围 三大重点领域的活动：1.基础科学，疫苗和治疗研究，2。 以患者为中心的临床研究，3。公共卫生和实施科学。我们的培训 该计划将包括每个NIH艾滋病毒/艾滋病研究重点的研究活动，以减少 艾滋病毒发病率，开发下一代艾滋病毒疗法，开展艾滋病毒治疗研究， 解决艾滋病毒相关的合并症，合并感染和并发症;但更重要的是，我们的计划 还将使学员接触艾滋病毒研究和团队科学的交叉领域，以加快翻译 转化为改善健康的成果。我们组建了一支由35名经验丰富的 导师横跨3个艾滋病毒研究重点领域，并为我们的学员设计了教学机会， 补充他们的研究项目，并扩大他们的理解板凳床边社区 艾滋病毒研究创新的翻译。此外，我们的培训项目的地理位置位于 周围有4个县被卫生和公共服务部命名为重点地区 结束艾滋病毒流行（EHE）倡议进一步表明了制定和支持下一个 艾滋病毒调查人员的一代，特别是在我们的机构。鉴于南方艾滋病毒流行病的严重性， 以及DHHS提出的在未来10年内结束美国艾滋病毒流行的新倡议， 在艾滋病研究领域培养下一代翻译型艾滋病科学家至关重要， 重要性博士后学员将从我们的T32计划中脱颖而出，为科学独立做好准备， 深入了解他们的研究如何融入多方向和多学科的框架， 艾滋病毒研究的长期目标是结束艾滋病毒的流行。

Project Abstract In this application entitled `Emory Training Program in Translational Research to End the HIV Epidemic', we propose a new T32 training program focused on translational HIV science located at the epicenter of the US HIV epidemic in the Southern US at Emory University in Atlanta, GA. Our training program will provide 2 years of support to 5 post-doctoral fellows and a summer internship opportunity for 2 pre-doctoral under- represented minority (URM) students to conduct cutting-edge HIV research through hands-on experience and formal didactics and also educate trainees on the broader context of HIV research across the translational continuum. Our training program will be fully integrated with and capitalize on the significant HIV research portfolio of the Emory Center for AIDS Research (CFAR) and span the spectrum of ongoing HIV research activities in 3 major areas of focus: 1. Laboratory-based basic science, vaccine, and cure research, 2. Patient-centered clinical research, and 3. Public health and implementation science. Our training program will encompass research activities in each of the NIH HIV/AIDS research priorities to reduce the incidence of HIV, develop next generation HIV therapeutics, conduct research towards an HIV cure, and address HIV associated co-morbidities, co-infections and complications; but, more importantly, our program will also expose trainees to cross-cutting areas of HIV research and team science to accelerate the translation of discovery into improved health outcomes. We have assembled a team of 35 diverse and experienced mentors across the 3 HIV research focus areas and designed didactic opportunities for our mentees to complement their research projects and expand their understanding of bench to bedside to community translation of HIV research innovation. In addition, the geographic position of our training program located in and surrounded by 4 of the counties named as focus areas for the Department of Health and Human Services Ending the HIV Epidemic (EHE) initiative further demonstrates the urgency to develop and support the next generation of HIV investigators specifically at our institution. Given the gravity of the HIV epidemic in the South and globally and the new DHHS initiative that proposes to end the US HIV epidemic in the next 10 years, fostering the next generation of translational HIV scientists across the HIV research continuum is of utmost importance. Post-doctoral trainees will emerge from our T32 program ready for scientific independence and with a deep understanding of how their research fits into the multidirectional and multidisciplinary framework of HIV research with the long-term goal of ending the HIV epidemic.