Preclinical Gap-Filling Services: Studies to Assess Interactions Between Dapivirine and Vaginally-Applied, Over-The-Counter Products

临床前填补空白服务：评估达匹韦林与阴道使用的非处方产品之间相互作用的研究

• 批准号: 10329785
• 负责人: MARIA GRAZIA FERRARI
• 金额: $ 27.19万
• 依托单位: ADVANCED BIOSCIENCE LABORATORIES, INC.
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-08-01 至 2021-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10329785
• 关键词: Animal Model; Collaborations; Contractor; Contracts; Dapivirine; Enzymes; Female genitalia; HIV; Investigator-Initiated Research; Metabolism; Miconazole; National Institute of Allergy and Infectious Disease; Permeability; Prevention; Reporting; Resources; Role; Services; Tissues; Vagina; international partnership; microbicide; pre-clinical; product development; reproductive tract; research study

The purpose of the Comprehensive Resources for Microbicides and Biomedical Prevention contract is to provide the NIAID with a comprehensive suite of preclinical product development services for candidate products that emerge from investigator-initiated research studies or from collaborations with outside companies or organizations. The Contractor shall provide: 1) Preclinical gap-filling services; 2) HIV animal models supporting product development; 3) Bioanalytical support services; 4) Product manufacturing; and 5) Scientific and quality/regulatory support services.

杀微生物剂和生物医学预防综合资源合同的目的是为NIAID提供一套全面的临床前产品开发服务，用于从制药商发起的研究或与外部公司或组织合作中产生的候选产品。承包商应提供：1）临床前填补空白服务; 2）支持产品开发的HIV动物模型; 3）生物分析支持服务; 4）产品制造;以及5）科学和质量/监管支持服务。