Enhancing Physical Activity Adoption and Maintenance in Adults with Obesity by Understanding Motivation for Exercise: A Mixed Methods Research Design

通过了解运动动机来加强肥胖成人体育活动的采用和维持：混合方法研究设计

• 批准号: 10341074
• 负责人: Danielle M Ostendorf
• 金额: $ 1.75万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-03-01 至 2022-04-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10341074
• 关键词: Accelerometer; Address; Adherence; Adoption; Adult; Affect; Behavioral; Body Weight decreased; Characteristics; Chronic Disease; Clinical Research; Clinical Trials; Colorado; Data; Data Analyses; Development; Enrollment; Environment; Epidemiology; Evaluation; Exercise; Focus Groups; Fostering; Frequencies; Future; Goals; Guidelines; Guilt; Health; Individual; Maintenance; Measures; Medical; Mentors; Mentorship; Methods; Modeling; Motivation; Obesity; Obesity Epidemic; Overweight; Participant; Persons; Physical activity; Preparation; Prevention; Psychosocial Factor; Public Health; Publications; Publishing; Qualitative Methods; Questionnaires; Regulation; Reporting; Research; Research Design; Research Methodology; Research Personnel; Research Training; Rewards; Risk; Self Determination; Statistical Methods; Theory of Change; Time; Training; Universities; Weight; Work; adult obesity; base; behavior change; career; design; exercise intervention; exercise prescription; experience; improved; innovation; method development; novel; novel strategies; person centered; prevent; programs; randomized controlled study; skill acquisition; skills; success; theories; therapy design; training opportunity; weight loss intervention

PROJECT SUMMARY/ABSTRACT Physical activity (PA) is one of the best predictors of sustained weight loss and current guidelines recommend high levels of PA to prevent weight regain after weight loss. However, long-term adherence to PA is generally poor when adults with overweight/obesity are provided an exercise prescription consistent with current guidelines. Thus, it is essential to evaluate novel strategies to enhance adoption and maintenance of PA in adults with overweight/obesity. The overall goal of this mentored F32 application is to use mixed methods research to optimize an innovative, theoretically based PA intervention designed to enhance motivation for exercise in adults with overweight/obesity. Specifically, quantitative data (Aim 1) will be integrated with qualitative data (Aim 2) to optimize an intervention designed to enhance MOtiVation for Exercise (MOVE) in adults with overweight/obesity (Aim 3). In Aim 1, a latent transition analysis will be used to examine longitudinal measures of motivation for exercise and objective PA data collected in 170 adults enrolled in a recently completed behavioral weight loss trial (R01DK097266). In Aim 2, adults from an ongoing behavioral weight loss trial (R01DK111622) will receive the MOVE intervention and participate in focus groups to explore how participants experience MOVE. In Aim 3, quantitative and qualitative results will be integrated to optimize MOVE. The applicant, Dr. Danielle Ostendorf, received graduate training in chronic disease epidemiology, clinical trial management, and person-centered analytical approaches including latent profile analysis. Dr. Ostendorf’s long-term goal is to develop an independent research program that focuses on the prevention and treatment of chronic diseases, including obesity, by improving strategies to increase PA. To build upon her graduate training and expand her scientific skillset, Dr. Ostendorf and her mentorship team have developed a comprehensive training plan. Dr. Ostendorf’s primary training objectives include obtaining training in: (1) additional direct clinical research experience, (2) behavior change theory and strategies, (3) latent transition analysis, a longitudinal extension of latent profile analysis, (4) qualitative data analysis and mixed methods research, and (5) strengthening granstmanship, publishing, and professional development skills. This research and training will take place at the University of Colorado Anschutz Medical Campus, an exceptional environment that offers endless world-class opportunities for Dr. Ostendorf to gain valuable skills and experiences that will foster her development as an independent researcher. Successful completion of this proposal will result in several first-authored publications and will generate critical preliminary data needed to support a competitive K01 application. This F32 proposal, with its focus on expanding Dr. Ostendorf’s expertise in advanced statistical methods and development of new research skills in mixed methods approaches, will serve as both a superb training opportunity and as an original and meaningful scientific contribution to propel Dr. Ostendorf’s career forward as an independent investigator.

项目总结/摘要 体力活动（PA）是持续减肥的最佳预测因子之一，目前的指南建议 高水平的PA，以防止体重减轻后体重反弹。然而，长期坚持PA通常 当向超重/肥胖的成年人提供与当前运动处方一致的运动处方时， 指南因此，有必要评估新的策略，以提高采用和维护的PA在成年人 超重/肥胖。这个指导F32应用程序的总体目标是使用混合方法研究， 优化一项创新的、基于理论的PA干预措施，旨在增强成年人的运动动机 超重/肥胖。具体而言，定量数据（目标1）将与定性数据（目标2）相结合， 优化旨在增强超重/肥胖成人运动动机（MOVE）的干预措施 (Aim 3）。在目标1中，潜在的转变分析将用于检查动机的纵向措施， 在最近完成的行为减肥中，收集了170名成年人的运动和客观PA数据 试验（R 01 DK 097266）。在目标2中，来自正在进行的行为减肥试验（R 01 DK 111622）的成年人将接受 MOVE干预，并参加焦点小组，以探讨参与者如何体验MOVE。在目标3中， 定量和定性结果将被整合，以优化MOVE。申请人丹妮尔奥斯滕多夫博士 接受慢性病流行病学，临床试验管理和以人为本的研究生培训 分析方法，包括潜在轮廓分析。奥斯滕多夫博士的长期目标是开发一种 一个独立的研究计划，重点是预防和治疗慢性疾病，包括 肥胖，通过改善策略，以增加PA。以她的研究生训练为基础， 奥斯滕多夫博士和她的导师团队已经制定了一个全面的培训计划。奥斯滕多夫医生 主要培训目标包括获得以下方面的培训：（1）额外的直接临床研究经验，（2） 行为改变理论与策略，（3）潜在转变分析，纵向延伸的潜在剖面 分析，（4）定性数据分析和混合方法研究，（5）加强宣传， 出版和专业发展技能。这项研究和培训将在哥伦比亚大学进行。 科罗拉多安舒茨医学院，一个特殊的环境，提供无尽的世界级的机会 奥斯滕多夫博士获得宝贵的技能和经验，将促进她作为一个独立的发展 研究员成功完成此提案将导致几个第一作者的出版物，并将 生成支持有竞争力的K 01应用程序所需的关键初步数据。这款F32的提案， 专注于扩展奥斯滕多夫博士在先进统计方法和新研究开发方面的专业知识 混合方法方法的技能，将作为一个极好的培训机会，并作为一个原始的， 有意义的科学贡献，以推动博士奥斯滕多夫的职业生涯向前作为一个独立的研究者。