The Administrative Core will support Udall Center activities at the University of Rochester

摘要 UR-Udall中心的行政核心将利用伊利诺伊大学现有的资源 罗切斯特健康技术中心(Chet)。在过去的25年里，切特开创了多中心 在120项研究中招募了40,000人的研究，导致了7项FDA批准的研究 治疗，包括给PD的四个治疗。最近，Chet使用技术来改变PD的研究和护理。 在这些PD倡议中，有一些疾病模型已经确定了新的临床和遗传标记 疾病进展，前两个虚拟PD研究，PD中最大的两个智能手机研究， 首个针对PD的纵向可穿戴传感器研究，也是唯一的全国性随机对照试验 为警局提供远程医疗。 该大学的戈尔根数据科学研究所和罗切斯特大学的临床和 翻译科学研究所将为行政核心提供支持。此外，一个多学科的网络 来自顶尖机构的领先研究人员，包括约翰·霍普金斯大学、阿斯顿大学和麻省理工学院，以及创新 23andMe和Sage Bionetworks等协作者将指导和协助执行UR-UDALL 中心的活动。 行政核心将在州、国家和全球层面开展无与伦比的外联活动。切特 将利用其覆盖全州的远程医疗网络，该网络为数百名健康专业人员短缺地区提供服务， 为他们所在社区的个人带来研究机会。与全国最大的倡导者合作 与其他组织合作，核心将使国家参与研究。使用其最近推出的帕金森电视， UR-Udall中心将覆盖全球100,000‘S个人，教育他们关于PD和新奇研究的知识。 最后，核心将利用神经病学系在实验中的T32奖学金计划 治疗，以及广泛的研究和职业发展机会，以组装和交叉培训 临床医生-科学家和10-20名计算机科学家、数学家和电气工程师在PD研究中 创建第一个既有临床研究又有计算科学的PD研究人员协作小组 专业知识。这种稀缺人力资本的涌入和发展将是UR-Udall中心众多 为这一领域做出了持久而宝贵的贡献。

SUMMARY The UR-Udall Center's Administrative Core will utilize the established resources of the University of Rochester's Center for Health + Technology (CHeT). Over the past 25 years, CHeT has pioneered multi-center research studies that have enrolled 40,000 individuals in 120 studies that have led to seven FDA-approved therapies, including four for PD. More recently, CHeT has used technology to transform PD research and care. Among these PD initiatives are disease models that have identified novel clinical and genetic markers of disease progression, the first two virtual PD research studies, the two largest smartphone studies in PD, the first longitudinal wearable sensor study for PD, and the only national randomized controlled trial of telemedicine for PD. The University's Goergen Data Science Institute and the University of Rochester's Clinical and Translational Science Institute will support the Administrative Core. In addition, a multidisciplinary network of leading investigators from top institutions, including Johns Hopkins, Aston University, and MIT, and innovative collaborators, such as 23andMe and Sage Bionetworks, will guide and assist with executing the UR-Udall Center's activities. The Administrative Core will conduct unparalleled outreach at the state, national, and global level. CHeT will utilize its statewide telemedicine network, which cares for hundreds in health professional shortage areas, to bring research opportunities to individuals in their communities. Working with the nation's largest advocacy organizations, the Core will enable national participation in research. Using its recently launched ParkinsonTV, the UR-Udall Center will reach 100,000's of individuals globally to educate them about PD and novel research. Finally, the Core will leverage the Department of Neurology's T32 fellowship program in experimental therapeutics, as well as extensive research and career development opportunities, to assemble and cross-train clinician-scientists and 10-20 computer scientists, mathematicians, and electrical engineers in PD research to create the first collaborative group of PD investigators with both clinical research and computational science expertise. This influx and development of scarce human capital will be one of the UR-Udall Center's many enduring and valuable contributions to the field.