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Social and Environmental Determinants of Breast Cancer Survivorship: The Black Breast Cancer Survivors Intervention

乳腺癌幸存者的社会和环境决定因素：黑人乳腺癌幸存者干预

基本信息

批准号：
10641582
负责人：
DEDE TETEH
金额：
$ 12.41万
依托单位：
CHAPMAN UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-09-01 至 2028-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10641582
关键词：
Address Advocacy Affect Aftercare Award Beauty Behavior Behavior Therapy Biological Black race Breast Cancer cell line Breast Cancer survivor Breast Cancer survivorship California Cancer Survivorship Caring Cell Proliferation Chemical Exposure Chemicals Cities Clinic Clinical Communities Comprehensive Cancer Center Development Diagnosis Disparity Dissemination and Implementation Doctor of Philosophy Educational Curriculum Endocrine Disruptors Endocrine system Environmental Exposure Ethnic Population Experimental Animal Model Exposure to Face Frequencies Goals Hair Hair Dyes Health Health Hazards Health behavior Human Immune system In Vitro Income Inequality Infrastructure Intervention Interview Invaded Knowledge Malignant Neoplasms Mentors Mentorship Outcome Parabens Population Intervention Procedures Quality of life Randomized Recurrence Reduce health disparities Reproduction Research Research Personnel Risk Risk Reduction Robin bird Sampling Scientist Structural Racism Surveys Survival Rate Survivors Training Universities Urine Virginia Woman Women&apos s Health black women breast cancer survival cancer health disparity cancer risk carcinogenicity career career development community based participatory research community based research community engagement community organizations community setting dissemination science estrogenic experience hazard health care availability health disparity implementation science improved informant intervention delivery malignant breast neoplasm migration negative affect peer personal care products post intervention pressure professor prototype psychologic psychosocial racial population randomized trial social social health determinants social influence survivorship tenure track therapy design trial design

项目摘要

PROJECT SUMMARY I am a tenure-track Assistant Professor at Chapman University, and adjunct Assistant Professor at City of Hope (COH) Comprehensive Cancer Center. I have expertise in health disparities, community engagement, and community-based participatory research including advocacy; cancer and cancer health disparities; cancer survivorship and clinic-based interventions. However, I have not developed, implemented, or analyzed a multi-level community-based intervention for Black breast cancer survivors. Black women face disparities in all stages of the cancer continuum and their survivorship needs remain unmet. Current research on endocrine disrupting chemicals (EDCs) in hair products indicate an increased risk and recurrence of breast cancer for Black women. There is also a dearth of psychosocial interventions that address the unique needs of Black breast cancer survivors. Behavioral interventions for this population lack content on identity, hair care, and harmful environmental exposures. Interventions are urgently needed for Black breast cancer survivors to address their unique survivorship journeys and reduce harmful environmental exposures during survivorship. My goals are to develop, implement and disseminate community-based interventions that improve quality of life (QOL) and address health behaviors related to Black identity that contribute to disparities affecting cancer risk and survivorship. As a first step towards these broad goals, with this K01 proposal, I seek to develop and evaluate an intervention to improve QOL and reduce adverse chemical exposures of EDCs found in personal care products of Black breast cancer survivors, post-treatment. The proposed career development and training plan support my trajectory toward becoming an independent, community-based implementation scientist with a focus on cancer health disparities through training and experience in 1) Designing community-based multi-level interventions; 2) Assessing environmental exposures in a community-based multi-level intervention; and 3) Using implementation science to evaluate community-based interventions for Black women. This project will take place at Chapman University with mentors who are experts in training and mentoring K01 trainees and assessing the psychological, biological and social influences on women’s health outcomes (Primary: Laura Glynn, PhD, Chapman University); randomized intervention designs (Co-Mentor: Virginia Sun, PhD, RN, COH); clinical implications of intervention design for Black breast cancer survivors (Co-Mentor: Abenaa Brewster, MD, MHS, MD Anderson); environmental exposures (Advisor: Robin Dodson, ScD, Silent Spring Institute); and dissemination and implementation science (Co-Mentor: Robert Newton, PhD, Pennington Biomedical).

项目摘要我是查普曼大学的终身助理教授，也是City of Hope的兼职助理教授 (COH)综合癌症中心。我在健康差距，社区参与，基于社区的参与性研究，包括宣传;癌症和癌症健康差异;癌症生存率和基于临床的干预。然而，我还没有开发、实施或分析一个为黑人乳腺癌幸存者提供多层次的社区干预。黑人妇女面临不平等在癌症的所有阶段，他们的生存需求仍未得到满足。内分泌研究现状头发产品中的干扰化学物质（EDCs）表明黑人患乳腺癌的风险和复发率增加妇女还缺乏满足黑胸患者独特需求的心理社会干预措施癌症幸存者对这一人群的行为干预缺乏关于身份、头发护理和有害健康的内容。环境暴露。黑人乳腺癌幸存者迫切需要采取干预措施，独特的生存旅程，减少生存过程中的有害环境暴露。我的目标是制定、实施和传播以社区为基础的干预措施，提高生活质量，解决与黑人身份有关的健康行为，这些行为导致影响癌症风险的差异，生存。作为实现这些广泛目标的第一步，通过K 01提案，我寻求开发和评估改善生活质量和减少个人护理中发现的EDCs的不良化学暴露的干预措施治疗后的黑人乳腺癌幸存者的产品。拟议职业发展和培训计划支持我成为一个独立的，以社区为基础的实施科学家，重点是通过培训和经验，1）设计基于社区的多层次（2）在以社区为基础的多层次干预中评估环境暴露; 3)利用实施科学评估黑人妇女的社区干预措施。这项目将在查普曼大学进行，导师是培训和指导K 01的专家评估心理、生物和社会对妇女健康结果的影响（主要：Laura Glynn，博士，查普曼大学）;随机干预设计（共同导师：Virginia Sun，博士，注册护士，COH）;干预设计对黑人乳腺癌幸存者的临床意义（共同导师：Abenaa 布鲁斯特，医学博士，MHS，医学博士安德森）;环境暴露（顾问：罗宾多德森，ScD，寂静的春天传播和实施科学（共同导师：罗伯特·牛顿博士，彭宁顿生物医学）。