Social and Environmental Determinants of Breast Cancer Survivorship: The Black Breast Cancer Survivors Intervention

项目总结 我是查普曼大学终身教席助理教授，也是希望之城的兼职助理教授 (COH)综合癌症中心。我在健康差距、社区参与和 基于社区的参与性研究，包括宣传；癌症和癌症健康差异；癌症 生存和基于临床的干预措施。但是，我还没有开发、实现或分析 黑人乳腺癌幸存者的多层次社区干预。黑人女性面临差异 在癌症连续体的所有阶段，其生存需求仍未得到满足。内分泌的研究现状 头发产品中的干扰化学物质(EDCs)表明黑人患乳腺癌的风险和复发增加 女人。解决黑乳房独特需求的心理社会干预也很缺乏。 癌症幸存者。对这一人群的行为干预缺乏关于身份认同、头发护理和有害的内容 暴露在环境中。黑人乳腺癌幸存者迫切需要干预措施来解决他们的 独一无二的求生旅程，减少求生过程中有害环境的暴露。我的目标是 制定、实施和传播以社区为基础的干预措施，以提高生活质量(QOL)和 解决与黑人身份相关的健康行为，这些行为会导致影响癌症风险和 生存能力。作为迈向这些广泛目标的第一步，通过这项K01提案，我寻求开发和评估 改善生活质量和减少个人护理中发现的内分泌细胞不良化学暴露的干预措施 黑人乳腺癌幸存者的产品，治疗后。拟议的职业发展和培训计划 支持我成为一名独立的、以社区为基础的实施科学家 通过培训和经验探讨癌症健康差距1)社区多层次设计 干预措施；2)在以社区为基础的多层次干预中评估环境暴露；以及 3)使用实施科学评估以社区为基础的黑人妇女干预措施。这 该项目将在查普曼大学进行，导师是培训和指导K01方面的专家 受训人员和评估对妇女健康结果的心理、生物和社会影响 (主要：劳拉·格林，查普曼大学博士)；随机干预设计(共同导师：弗吉尼亚·孙， 博士、RN、COH)；黑人乳腺癌幸存者干预设计的临床意义(共同导师：Abenaa 环境暴露(顾问：罗宾·多德森，SCD，寂静之春 传播和实施科学(共同导师：罗伯特·牛顿博士，彭宁顿 生物医学)。

PROJECT SUMMARY I am a tenure-track Assistant Professor at Chapman University, and adjunct Assistant Professor at City of Hope (COH) Comprehensive Cancer Center. I have expertise in health disparities, community engagement, and community-based participatory research including advocacy; cancer and cancer health disparities; cancer survivorship and clinic-based interventions. However, I have not developed, implemented, or analyzed a multi-level community-based intervention for Black breast cancer survivors. Black women face disparities in all stages of the cancer continuum and their survivorship needs remain unmet. Current research on endocrine disrupting chemicals (EDCs) in hair products indicate an increased risk and recurrence of breast cancer for Black women. There is also a dearth of psychosocial interventions that address the unique needs of Black breast cancer survivors. Behavioral interventions for this population lack content on identity, hair care, and harmful environmental exposures. Interventions are urgently needed for Black breast cancer survivors to address their unique survivorship journeys and reduce harmful environmental exposures during survivorship. My goals are to develop, implement and disseminate community-based interventions that improve quality of life (QOL) and address health behaviors related to Black identity that contribute to disparities affecting cancer risk and survivorship. As a first step towards these broad goals, with this K01 proposal, I seek to develop and evaluate an intervention to improve QOL and reduce adverse chemical exposures of EDCs found in personal care products of Black breast cancer survivors, post-treatment. The proposed career development and training plan support my trajectory toward becoming an independent, community-based implementation scientist with a focus on cancer health disparities through training and experience in 1) Designing community-based multi-level interventions; 2) Assessing environmental exposures in a community-based multi-level intervention; and 3) Using implementation science to evaluate community-based interventions for Black women. This project will take place at Chapman University with mentors who are experts in training and mentoring K01 trainees and assessing the psychological, biological and social influences on women’s health outcomes (Primary: Laura Glynn, PhD, Chapman University); randomized intervention designs (Co-Mentor: Virginia Sun, PhD, RN, COH); clinical implications of intervention design for Black breast cancer survivors (Co-Mentor: Abenaa Brewster, MD, MHS, MD Anderson); environmental exposures (Advisor: Robin Dodson, ScD, Silent Spring Institute); and dissemination and implementation science (Co-Mentor: Robert Newton, PhD, Pennington Biomedical).