Iowa Cochlear Implant Clinical Research Center - VIII

项目负责人/主要研究者（最后一位、第一位、中间一位）：J. J. J.布鲁斯。 项目概要-核心B 核心B的主要职责是招募受试者人群;为这些人群提供临床服务 受试者;维持人工耳蜗植入（CI）研究登记;监测术后残余听力;并获得 听力学和言语感知结果的措施，将在研究项目中使用。核心B将 并为所有调查人员提供技术和统计支持。这四个研究项目高度 相互依存和相互关联。每个项目都依赖于其他项目生成的数据来解决其问题 特定目的，使用相似的受试者人群来解决爱荷华州髋关节植入物临床研究 红十字国际委员会的总体目标。 本文描述了（1）受试者招募所需的广泛术前评价;（2）特定 研究的人群;（3）使用的CI;（4）基本听力学和言语感知结果指标， 将从受试者获得的性能;（5）受试者参与的时间线。整体 还讨论了统计设计、数据管理和技术支持。个别项目描述 具体的研究问题，以及每个项目如何相互作用和相互依赖。

Program Director/Principal Investigator (Last, First, Middle): Gantz, Bruce J. PROJECT SUMMARY – CORE B Core B's primary responsibilities are to accrue a subject population; provide the clinical service for these subjects; maintain a cochlear implant (CI) research registry; monitor postoperative residual hearing; and obtain audiologic and speech perception outcome measures that will be used in the research projects. Core B will also provide the technical and statistical support for all investigators. The four research projects are highly interdependent and interrelated. Each project depends on data generated by the others to address their specific aims, using similar subject populations to address the Iowa Cochlear Implant Clinical Research Center's (ICICRC) overall goals. Described here are (1) extensive preoperative evaluations required for subject accrual; (2) specific populations to be studied; (3) CIs to be used; (4) basic audiologic and speech perception outcome measures of performance that will be obtained from subjects; and (5) the time-line of subject involvement. The overall statistical design, data management and technical support are also discussed. The individual projects describe the specific research questions and how each project is interactive and dependent on the others.