A Unique, Co-Designed Family-Based Therapy for Marginalized Women with Opioid Use Disorder and Justice-Involvement

针对患有阿片类药物使用障碍和正义参与的边缘化妇女的独特的、共同设计的基于家庭的疗法

• 批准号: 10644331
• 负责人: Aaron William Murnan
• 金额: $ 19.21万
• 依托单位: UNIVERSITY OF CINCINNATI
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-06-15 至 2028-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10644331
• 关键词: Address; Affect; Aftercare; Ambulatory Care; Area; Award; Behavior Therapy; Child; Communities; Conflict (Psychology); Criminal Justice; Data; Decision Making; Dedications; Discipline of Nursing; Diversion Program; Doctor of Philosophy; Enrollment; Environment; Family; Family member; Feedback; Funding; Goals; Health; Health Promotion; Home; Homicide; Individual; Intervention; Intervention Studies; Interview; Justice; Manuals; Mental Health; Mentored Patient-Oriented Research Career Development Award; Mentors; Mentorship; Methodology; Methods; Mothers; Motivation; National Institute of Drug Abuse; Opioid; Outcome; Outcome Measure; Overdose; Participant; Personal Satisfaction; Population; Positioning Attribute; Premature Mortality; Process; Prostitution; Public Health; Publishing; Randomized; Randomized, Controlled Trials; Recording of previous events; Recovery; Relapse; Reporting; Research; Research Methodology; Research Personnel; Risk; Scientist; Seasons; Site; Strategic Planning; Support System; System; Training; Trauma; Treatment outcome; Universities; Victimization; Violence; Vulnerable Populations; Woman; Work; acceptability and feasibility; career; college; community based participatory research; comorbidity; design; effective intervention; experience; family support; feasibility trial; group intervention; health disparity; improved; innovation; marginalization; marginalized population; medication for opioid use disorder; member; neglect; novel; opioid epidemic; opioid use; opioid use disorder; pilot test; preference; professor; programs; prospective; prostitute; prototype; recidivism; recruit; response; satisfaction; sex; skills; sobriety; substance use; substance use treatment; sustained recovery; tenure track; therapy development; treatment arm

Project Summary/Abstract Aaron Murnan, PhD, LMFT is a tenure-track assistant professor at University of Cincinnati's College of Nursing. His career goal is to become an independent clinician-scientist with expertise in co-designing novel interventions to address salient treatment needs among families disproportionately impacted by opioid use and justice-involvement, specifically women in the sex trade. The term `co-design' refers to a community-based participatory research methodology in which individuals with lived experience are engaged as study team members to lend their hands-on expertise and thoroughly participate in the intervention development process. Given well-documented risks associated with the sex trade and opioid use, as well as a lack of interventions prospectively designed to address challenges experienced by this population, the current study represents a critical next step towards promoting the health and well-being of women in the sex trade. The proposed five- year Mentored Patient-Oriented Research Career Development Award (K23) will provide Dr. Murnan a perfect opportunity to achieve his career goals through training in: 1) Community-Based Participatory Research; 2) ADAPT-ITT substance use intervention adaptation methodologies; and 3) conducting research within the criminal justice system. Dr. Murnan's proposed study aims to evaluate the feasibility and acceptability of co- designed family-based intervention offered as an adjunct to treatment diversion programming (offered through the criminal justice system) using a pilot RCT design. In Aim 1, participant family dyads (n=15 women paired with one supportive family member) will be recruited to explore intervention needs, motivations, and barriers related to participating in family-based intervention, as well as delivery preferences. This information will be used by the co-design team (individuals with lived experience, the PI, and other research personnel) to adapt a family-based intervention manual. For Aim 2, additional family dyads (n=60) will be recruited to participate in a randomized controlled trial in which they will be randomly assigned to one of two treatment arms: 1) co- designed family-based intervention + diversion treatment programming or 2) diversion treatment programming only. Feasibility, acceptability, and preliminary efficacy of both interventions will be evaluated (Aim 2). Dr. Melinda Butsch Kovacic, a leading expert in community-based participatory research, will serve as Dr. Murnan's primary site mentor. Dr. Butsch Kovacic in conjunction with his co-mentors (Drs. Jennifer Brown and Sarah Manchak) will provide him with necessary training in areas of community-based participatory research, substance use intervention adaptation methodologies, and conducting research within the criminal justice system, that will launch his independent research career as a clinician scientist with the requisite skills to conduct high quality intervention research to promote best outcomes among families disproportionately impacted by opioid use and criminal justice involvement.

项目总结/摘要 Aaron Murnan博士，LMFT是辛辛那提大学医学院的终身助理教授。 护理学他的职业目标是成为一名独立的临床科学家，拥有共同设计小说的专业知识。 采取干预措施，解决受阿片类药物使用影响过大的家庭的突出治疗需求， 司法介入，特别是性交易中的妇女。“共同设计”一词是指基于社区的 参与式研究方法，具有生活经验的个人作为研究团队参与其中 委员会鼓励成员提供他们的实际专业知识，并全面参与干预措施的制定过程。 鉴于与性交易和阿片类药物使用相关的风险以及缺乏干预措施， 前瞻性设计，以解决这一人群所经历的挑战，目前的研究代表了一个 这是促进性交易中妇女健康和福祉的关键下一步。建议的五个- 一年的指导以病人为导向的研究职业发展奖（K23）将提供博士。 通过以下培训实现职业目标的机会：1）以社区为基础的前瞻性研究; 2） ADAPT-ITT物质使用干预适应方法;以及3）在 刑事司法系统。Murnan博士提出的研究旨在评估联合治疗的可行性和可接受性。 作为治疗转移方案的辅助手段提供的设计好的基于家庭的干预措施（通过 刑事司法系统）使用随机对照试验设计。在目标1中，参与者家庭二人组（n=15名女性配对 有一个支持的家庭成员）将被招募，以探索干预的需求，动机和障碍 与参与以家庭为基础的干预措施以及交付偏好有关。此信息将 由共同设计团队（具有实际经验的个人、PI和其他研究人员）使用， 家庭干预手册。对于目标2，将招募额外的家庭二元组（n=60）参加一项 随机对照试验，其中他们将被随机分配到两个治疗组之一：1）共同 设计的以家庭为基础的干预+转移治疗方案或2）转移治疗方案 只.将评价两种干预措施的可行性、可接受性和初步疗效（目标2）。博士 梅林达·布奇·科瓦契奇，一位以社区为基础的参与性研究的领先专家，将担任博士。 穆南的主要网站导师。Butsch Kovacic博士与他的共同导师（Jennifer Brown博士和 Sarah Manchak）将为他提供以社区为基础的参与性研究领域的必要培训， 药物使用干预适应方法，并在刑事司法范围内开展研究 系统，这将启动他的独立研究生涯作为一个临床科学家与必要的技能， 进行高质量的干预研究，以促进不成比例的家庭取得最佳成果 受阿片类药物使用和刑事司法参与的影响。