Development and Pilot Testing of a Mental Health Clinic-Based PrEP Uptake and Adherence Intervention for Women in Treatment for Trauma-Related Conditions

针对治疗创伤相关疾病的女性,开发和试点基于心理健康诊所的 PrEP 摄取和依从性干预措施

基本信息

项目摘要

Pre-exposure prophylaxis (PrEP) is a highly effective HIV prevention tool but is not widely accessed by women. Women in the southern United States account for 55% of annual HIV diagnoses, and violence and trauma are consistently linked with increased HIV risk in these women. The long-term goal is to establish a new treatment delivery model that integrates biomedical HIV prevention services into mental health care settings, thus removing individual and provider- level barriers to PrEP care for women with trauma-related conditions who are at risk for HIV through problematic substance use or risky sexual behaviors. The overall objectives are to (i) elucidate individual and provider level barriers to PrEP uptake and adherence and, guided by the Information-Motivation-Behavioral Skills (IMB) model, (ii) establish a mental health clinic-based behavioral intervention for increasing PrEP uptake and adherence in this population. The central hypothesis is that, compared to standard treatment, an intervention delivered within the mental health treatment setting that integrates knowledge, behavioral skills, and motivation to engage in and adhere to PrEP care will result in a greater proportion of participants who fill their first PrEP prescription. In Year 1, we will conduct Stage 1A research to identify key issues to address in developing the integrated treatment. Interview data obtained from women undergoing mental health treatment for trauma-related conditions and their treatment providers will be used to finalize the design of the pilot trial (Stage 1B) comparing standard treatment to the integrated (mental health treatment and HIV prevention) intervention. The new integrated intervention will include motivational counseling guided by the IMB Model which seeks to influence behavior change via information sharing, increasing motivation for change, and teaching behavioral skills to increase self-efficacy. To test the hypothesis, the following specific aims will be pursued: (1) Collect information on knowledge and attitudes about PrEP use and obtain feedback about the potential design of the integrated behavioral intervention from women undergoing treatment for trauma-related conditions who are at risk for HIV and their; and (2) Develop an integrated behavioral intervention to promote PrEP uptake and adherence in women undergoing treatment for trauma-related conditions who are at high risk for HIV; and (3) Assess feasibility, acceptability and initial efficacy of the intervention. The research proposed in this application, in the applicant’s opinion, is innovative in that the mental health treatment setting is ideally situated to provide additional services for HIV prevention including PrEP but, to our knowledge, full integration of PrEP services into mental health treatment for women has not been evaluated. The research is significant because it is expected to provide scientific justification for the continued development of behavioral interventions tailored to the unique needs of women who have experienced trauma. Ultimately, such research can inform the development of innovative strategies to improve uptake of effective HIV prevention strategies.
暴露前预防(PrEP)是一种非常有效的艾滋病毒预防工具,但妇女并不广泛使用。妇女 在美国南部,每年的艾滋病诊断占55%,暴力和创伤一直与之相关。 这些妇女感染艾滋病毒的风险增加。长期目标是建立一种新的治疗模式, 将生物医学艾滋病毒预防服务纳入精神卫生保健环境,从而消除个人和提供者- 为患有创伤相关疾病的妇女提供PrEP护理的水平障碍,这些妇女通过有问题的 物质使用或危险的性行为。总体目标是:(一)阐明个人和供应商层面的障碍, PrEP吸收和坚持,并在信息-动机-行为技能(IMB)模型的指导下,(ii)建立一个 基于心理健康诊所的行为干预,以增加该人群的PrEP吸收和依从性。的 中心假设是,与标准治疗相比,在心理健康治疗中提供的干预 整合知识,行为技能和参与和坚持PrEP护理的动机的设置将导致 更大比例的参与者填写他们的第一个PrEP处方。在第一年,我们将进行1A阶段的研究, 确定在制定综合治疗方案时要解决的关键问题。访谈数据来自接受手术的妇女 创伤相关疾病的心理健康治疗及其治疗提供者将用于完成 试点试验(第1B阶段),比较标准治疗与综合治疗(心理健康治疗和艾滋病毒预防) 干预新的综合干预措施将包括由IMB模式指导的动机咨询, 通过信息共享,增加改变的动机和教授行为技能来影响行为改变, 提高自我效能。为了检验这一假设,将追求以下具体目标: 关于PrEP使用的知识和态度,并获得有关综合行为的潜在设计的反馈 对正在接受创伤相关疾病治疗的妇女进行干预,这些妇女有感染艾滋病毒的风险;以及(2) 制定综合行为干预措施,以促进正在接受PrEP治疗的女性的PrEP吸收和依从性 (3)评估艾滋病毒感染高危人群的创伤相关情况的可行性、可接受性和初步疗效。 干预申请人认为,本申请中提出的研究具有创新性,因为心理健康 治疗环境的理想位置是提供额外的艾滋病毒预防服务,包括PrEP,但我们的 然而,尚未评估将PrEP服务充分纳入妇女心理健康治疗的情况。的 研究是重要的,因为它预计将提供科学的理由,继续发展, 针对经历过创伤的妇女的独特需求采取的行为干预措施。最终,这样的研究 可以为制定创新战略提供信息,以提高对有效艾滋病毒预防战略的接受程度。

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ monograph.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ sciAawards.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ conferencePapers.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ patent.updateTime }}

Ronald E. Acierno其他文献

A Multimedia Program To Improve Criminal Justice System Participation and Reduce Distress Among Physically Injured Crime Victims
多媒体计划旨在提高刑事司法系统的参与度并减少身体受伤的犯罪受害者的痛苦
  • DOI:
  • 发表时间:
    2006
  • 期刊:
  • 影响因子:
    0
  • 作者:
    C. Best;Ronald E. Acierno;Heidi S. Resnick
  • 通讯作者:
    Heidi S. Resnick

Ronald E. Acierno的其他文献

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

{{ truncateString('Ronald E. Acierno', 18)}}的其他基金

Development and Pilot Testing of a Mental Health Clinic-Based PrEP Uptake and Adherence Intervention for Women in Treatment for Trauma-Related Conditions
针对治疗创伤相关疾病的女性,开发和试点基于心理健康诊所的 PrEP 摄取和依从性干预措施
  • 批准号:
    10327505
  • 财政年份:
    2021
  • 资助金额:
    $ 23.4万
  • 项目类别:
Behavioral Activation Delivered via Home-based Telehealth to Improve Functioning inCardiovascular Disease Patients Recently Discharged from Inpatient Care
通过家庭远程医疗提供行为激活,以改善最近出院的心血管疾病患者的功能
  • 批准号:
    10598077
  • 财政年份:
    2021
  • 资助金额:
    $ 23.4万
  • 项目类别:
Behavioral Activation Delivered via Home-based Telehealth to Improve Functioning in Cardiovascular Disease Patients Recently Discharged from Inpatient Care
通过家庭远程医疗提供行为激活,以改善最近出院的心血管疾病患者的功能
  • 批准号:
    10405517
  • 财政年份:
    2021
  • 资助金额:
    $ 23.4万
  • 项目类别:
Development and Pilot Testing of a Mental Health Clinic-Based PrEP Uptake and Adherence Intervention for Women in Treatment for Trauma-Related Conditions
针对治疗创伤相关疾病的女性,开发和试点基于心理健康诊所的 PrEP 摄取和依从性干预措施
  • 批准号:
    10441606
  • 财政年份:
    2021
  • 资助金额:
    $ 23.4万
  • 项目类别:
Behavioral Activation Delivered via Home-based Telehealth to Improve Functioning in Cardiovascular Disease Patients Recently Discharged from Inpatient Care
通过家庭远程医疗提供行为激活,以改善最近出院的心血管疾病患者的功能
  • 批准号:
    10312861
  • 财政年份:
    2021
  • 资助金额:
    $ 23.4万
  • 项目类别:
Treatment of Prolonged Grief Disorder in Combat Veterans
退伍军人长期悲伤症的治疗
  • 批准号:
    8811499
  • 财政年份:
    2015
  • 资助金额:
    $ 23.4万
  • 项目类别:
Prolonged Exposure (PE) for PTSD: Telemedicine vs. In Person
PTSD 的长期暴露 (PE):远程医疗与面对面医疗
  • 批准号:
    8225409
  • 财政年份:
    2010
  • 资助金额:
    $ 23.4万
  • 项目类别:
Prolonged Exposure (PE) for PTSD: Telemedicine vs. In Person
PTSD 的长期暴露 (PE):远程医疗与面对面医疗
  • 批准号:
    7869805
  • 财政年份:
    2010
  • 资助金额:
    $ 23.4万
  • 项目类别:
Prolonged Exposure (PE) for PTSD: Telemedicine vs. In Person
PTSD 的长期暴露 (PE):远程医疗与面对面医疗
  • 批准号:
    8598427
  • 财政年份:
    2010
  • 资助金额:
    $ 23.4万
  • 项目类别:
Prolonged Exposure (PE) for PTSD: Telemedicine vs. In Person
PTSD 的长期暴露 (PE):远程医疗与面对面医疗
  • 批准号:
    8698782
  • 财政年份:
    2010
  • 资助金额:
    $ 23.4万
  • 项目类别:

相似海外基金

Pharmacy-led Transitions of Care Intervention to Address System-Level Barriers and Improve Medication Adherence in Socioeconomically Disadvantaged Populations
药房主导的护理干预转型,以解决系统层面的障碍并提高社会经济弱势群体的药物依从性
  • 批准号:
    10594350
  • 财政年份:
    2023
  • 资助金额:
    $ 23.4万
  • 项目类别:
Evaluating Centralizing Interventions to Address Low Adherence to Lung Cancer Screening Follow-up in Decentralized Settings
评估集中干预措施,以解决分散环境中肺癌筛查随访依从性低的问题
  • 批准号:
    10738120
  • 财政年份:
    2023
  • 资助金额:
    $ 23.4万
  • 项目类别:
Suubi-Mhealth: A mobile health intervention to address depression and improve ART adherence among Youth living with HIV (YLHIV) in Uganda
Suubi-Mhealth:一种移动健康干预措施,旨在解决乌干达艾滋病毒感染者 (YLHIV) 青少年的抑郁症问题并提高抗逆转录病毒疗法的依从性
  • 批准号:
    10526768
  • 财政年份:
    2022
  • 资助金额:
    $ 23.4万
  • 项目类别:
Suubi-Mhealth: A mobile health intervention to address depression and improve ART adherence among Youth living with HIV (YLHIV) in Uganda
Suubi-Mhealth:一种移动健康干预措施,旨在解决乌干达艾滋病毒感染者 (YLHIV) 青少年的抑郁症问题并提高抗逆转录病毒疗法的依从性
  • 批准号:
    10701072
  • 财政年份:
    2022
  • 资助金额:
    $ 23.4万
  • 项目类别:
A behavioral intervention for Black men who have sex with men and live with HIV to address intersectional stigma and improve antiretroviral therapy adherence
针对男男性行为且感染艾滋病毒的黑人男性进行行为干预,以解决交叉耻辱并提高抗逆转录病毒治疗的依从性
  • 批准号:
    10679092
  • 财政年份:
    2021
  • 资助金额:
    $ 23.4万
  • 项目类别:
A behavioral intervention for Black men who have sex with men and live with HIV to address intersectional stigma and improve antiretroviral therapy adherence
针对男男性行为且感染艾滋病毒的黑人男性进行行为干预,以解决交叉耻辱并提高抗逆转录病毒治疗的依从性
  • 批准号:
    10432133
  • 财政年份:
    2021
  • 资助金额:
    $ 23.4万
  • 项目类别:
A behavioral intervention for Black men who have sex with men and live with HIV to address intersectional stigma and improve antiretroviral therapy adherence
针对男男性行为且感染艾滋病毒的黑人男性进行行为干预,以解决交叉耻辱并提高抗逆转录病毒治疗的依从性
  • 批准号:
    10327065
  • 财政年份:
    2021
  • 资助金额:
    $ 23.4万
  • 项目类别:
Leveraging Technology to Address Access and Adherence to Conventional Hospital-Based Pulmonary Rehabilitation in Veterans with COPD
利用技术解决慢性阻塞性肺病退伍军人接受和坚持传统医院肺康复的问题
  • 批准号:
    10377366
  • 财政年份:
    2019
  • 资助金额:
    $ 23.4万
  • 项目类别:
Leveraging Technology to Address Access and Adherence to Conventional Hospital-Based Pulmonary Rehabilitation in Veterans with COPD
利用技术解决慢性阻塞性肺病退伍军人接受和坚持传统医院肺康复的问题
  • 批准号:
    10574496
  • 财政年份:
    2019
  • 资助金额:
    $ 23.4万
  • 项目类别:
Targeted interventions to address the multi-level effects of gender-based violence on PrEP uptake and adherence among adolescent girls and young women in Kenya
有针对性的干预措施,以解决性别暴力对肯尼亚少女和年轻妇女接受和坚持 PrEP 的多层面影响
  • 批准号:
    9403567
  • 财政年份:
    2017
  • 资助金额:
    $ 23.4万
  • 项目类别:
{{ showInfoDetail.title }}

作者:{{ showInfoDetail.author }}

知道了