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Duke Radiation Oncology and Radiology Stimulating Access to Research in Residency

杜克大学放射肿瘤学和放射学促进住院医师研究的机会

基本信息

批准号：
10647795
负责人：
Scott R Floyd
金额：
$ 55.88万
依托单位：
DUKE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-02-05 至 2024-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10647795
关键词：
Academic Medical Centers Address Advanced Malignant Neoplasm American Applications Grants Area Basic Science Biomedical Engineering Board Certification Cancer Biology Cancer Detection Cancer Patient Certification Clinical Research Clinical Sciences Communication Communities Dedications Detection Development Development Plans Diagnosis Diagnostic radiologic examination Discipline Doctor of Philosophy Eligibility Determination Ensure Extramural Activities Faculty Fellowship Fostering Funding Future Goals Grant Image Individual Institution Interventional radiology Investigation Journals Lead Malignant Neoplasms Manuscripts Mentors Mission Pathway interactions Patients Physicians Physicians&apos Offices Play Positioning Attribute Radiation Oncologist Radiation Oncology Radiation therapy Radiobiology Radiology Specialty Research Research Personnel Research Priority Research Project Grants Research Training Residencies Resources Role Scholarship Scientist Staging Talents Therapeutic Time Training Translational Research Universities Wages Writing anticancer research cancer diagnosis cancer therapy career career development clinical development clinical training diagnostic strategy didactic education early phase clinical trial experience image guided image guided therapy imaging approach imaging program imaging study improved innovation instructor interest medical schools medical specialties meetings multidisciplinary next generation novel novel diagnostics novel therapeutic intervention oncology program preclinical imaging preference programs radiologist response success translational study

项目摘要

Advances in imaging and radiation therapy have the potential to spark widespread improvements in cancer diagnosis and treatment. However, a major barrier to progress in Radiation Oncology and Radiology is a shortage of physician-scientists with the necessary training to make transformative discoveries. Therefore, there is an urgent need to develop novel pathways for extended mentored research to retain more radiation oncologists and radiologists in research. To address this gap, we propose a Duke Radiation Oncology and Radiology Stimulating Access to Research in Residency (Duke ROR StARR) Program, with its central mission to cultivate Resident-Investigators in Radiation Oncology and Radiology through protected time to perform mentored research, therefore creating a cadre of physician-scientists who will make future discoveries that advance imaging and treatment of cancer. With a multi-departmental strategy spanning clinical and basic science departments, Resident-Investigators will experience individualized, multifaceted, and continuous training, embedded within a robust, institutional framework for physician scientist support. A team of multi- disciplinary, well-funded faculty Preceptors, as well as a group of talented Rising Preceptors, offer research opportunities in areas along the cancer research continuum from basic radiation and cancer biology, to pre- clinical imaging and translational studies, to early phase clinical trials. These areas address NCI strategic research priorities that include dissecting pathobiological mechanisms of cancer and developing novel diagnostic and therapeutic strategies. The program will consist of five training Aims: (1) Comprehensive didactics on professional development and basic, translational, and clinical research; (2) A research project and individual career development plan; (3) Scholarly activity; (4) Board eligibility for the American Board of Radiology; and (5) A path for continued post-residency mentored research training with sub-specialty clinical development. Led by PI David Kirsch (Radiation Oncology), Associate Program Directors Joseph Lo (Radiology) and Scott Floyd (Radiation Oncology), and departmental Residency Program Directors, the program will support three Resident-Investigators in Radiation Oncology, Diagnostic Radiology and/or Interventional Radiology per year, who will complete 12-24 months of mentored research. Institutional support including resources from the Office of Physician Scientist Development, departmental salary support, a research supplement funded by the School of Medicine, and preferences for a subspecialty fellowship or research-intensive Instructor position at Duke supported by the Duke Cancer Institute will ensure that after completing the program, these individuals will be poised to become the next generation of physicians to lead research in Radiation Oncology and Radiology. Achieving the Program's objectives will fulfill urgent needs for: 1) more physician-scientists in Radiation Oncology and Radiology and 2) innovations in imaging, cancer biology, and radiation oncology to transform the lives of cancer patients.

成像和放射治疗的进步有可能引发癌症的广泛改善

项目成果

期刊论文数量（10）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Factors Associated With New-Onset Seizures Following Stereotactic Radiosurgery for Newly Diagnosed Brain Metastases.

DOI：
10.1016/j.adro.2022.101054
发表时间：
2022-11
期刊：
ADVANCES IN RADIATION ONCOLOGY
影响因子：
2.3
作者：
Lerner, Emily C;Srinivasan, Ethan S;Broadwater, Gloria;Haskell-Mendoza, Aden P;Edwards, Ryan M;Huie, David;Vaios, Eugene J;Floyd, Scott R;Adamson, Justus D;Fecci, Peter E
通讯作者：
Fecci, Peter E

Combination laser interstitial thermal therapy plus stereotactic radiotherapy increases time to progression for biopsy-proven recurrent brain metastases.

DOI：
10.1093/noajnl/vdac086
发表时间：
2022-01
期刊：
Neuro-oncology advances
影响因子：
0
作者：
通讯作者：

Novel Mechanisms and Future Opportunities for the Management of Radiation Necrosis in Patients Treated for Brain Metastases in the Era of Immunotherapy.

DOI：
10.3390/cancers15092432
发表时间：
2023-04-24
期刊：
Cancers
影响因子：
5.2
作者：
通讯作者：

Outcomes in Patients with Intact and Resected Brain Metastasis Treated with 5-Fraction Stereotactic Radiosurgery.

采用 5 分次立体定向放射外科治疗的完整脑转移瘤和已切除脑转移瘤患者的结果。

DOI：
10.1016/j.adro.2022.101166
发表时间：
2023-03
期刊：
Advances in radiation oncology
影响因子：
2.3
作者：
通讯作者：

Prognostic Model for Intracranial Progression after Stereotactic Radiosurgery: A Multicenter Validation Study.

DOI：
10.3390/cancers14215186
发表时间：
2022-10-22
期刊：
CANCERS
影响因子：
5.2
作者：
Carpenter, David J.;Natarajan, Brahma;Arshad, Muzamil;Natesan, Divya;Schultz, Olivia;Moravan, Michael J.;Read, Charlotte;Lafata, Kyle J.;Giles, Will;Fecci, Peter;Mullikin, Trey C.;Reitman, Zachary J.;Kirkpatrick, John P.;Floyd, Scott R.;Chmura, Steven J.;Hong, Julian C.;Salama, Joseph K.
通讯作者：
Salama, Joseph K.