UW Comprehensive CANCER CENTER SUPPORT

项目概要/摘要 威斯康星州Carbone癌症中心（UWCCC）的大学寻求继续资助年44-48在 追求其使命，以大大减少癌症的负担内外其集水区。UWCCC， 该中心是威斯康星州大学医学与公共卫生学院（SMPH）的矩阵中心， 由来自威斯康星大学麦迪逊分校38个系和8个学院的198名教师组成 （UW）。我们的成员通过6个科学项目（人类癌症）进行癌症护理，研究和教育 病毒学，癌症遗传和表观遗传机制，肿瘤微环境，成像和放射 科学，发展治疗学和癌症预防和控制）由10个共享的支持 资源在2012-2016年期间，我们的成员发表了3324篇癌症相关稿件（占66%）， 合作），并得到6370万美元（直接）同行评审癌症相关资金和1660万美元（直接） 非同行评审资金（截至2016年12月31日）。 UWCCC将通过培养一个支持癌症的社区，可靠的 基础设施和高效资源。UWCCC致力于减少我们流域的癌症负担 通过优先研究领域（如创新疗法和生物标志物，癌症成像和 扩大以人群为基础的癌症研究），增强研究平台（例如，改进临床研究 基础设施和共享资源），加强努力建立与特派团有关的慈善事业，扩大当地 全球伙伴关系。

PROJECT SUMMARY/ABSTRACT The University of Wisconsin Carbone Cancer Center (UWCCC) seeks continued funding for years 44-48 in pursuit of its mission to dramatically reduce the burden of cancer within and beyond its catchment. The UWCCC, which is a matrix center within the University of Wisconsin School of Medicine and Public Health (SMPH), is composed of 198 faculty members from 38 departments and 8 schools of the University of Wisconsin-Madison (UW). Our members pursue cancer care, research and education through 6 scientific programs (Human Cancer Virology, Cancer Genetic and Epigenetic Mechanisms, Tumor Microenvironment, Imaging and Radiation Sciences, Developmental Therapeutics, and Cancer Prevention and Control) supported by 10 Shared Resources. During the period 2012-2016, our members published 3324 cancer relevant manuscripts (with 66% collaborative) and were supported by $63.7M (Direct) peer-reviewed cancer relevant funding and $16.6M (Direct) non peer-reviewed funding (as of December 31, 2016). The UWCCC will accomplish this mission through nurturing a supportive cancer community, reliable infrastructure, and efficient resources. The UWCCC worked to decrease the burden of cancer in our catchment and beyond through prioritized research areas (e.g. innovative therapies and biomarkers, cancer imaging and expanded population-based cancer research), enhanced research platforms (e.g. improved clinical research infrastructure and shared resources), increased efforts to build mission-related philanthropy and expanded local to global partnerships.