Core A: Administration

核心A：管理

• 批准号: 10522805
• 负责人: Reuben S Harris
• 金额: $ 750.56万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-05-16 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10522805
• 关键词: 2019-nCoV; Agreement; Annual Reports; Antiviral Agents; Biometry; Budgets; Businesses; COVID-19 pandemic; COVID-19 treatment; Clip; Collaborations; Communication; Communities; Conflict (Psychology); Consult; Consultations; Data Analyses; Decision Making; Development; Discipline; Disease Outbreaks; Educational workshop; Electronic Mail; Elements; Event; Experimental Designs; Future; Geographic Locations; Goals; Grant; Group Homes; Human Resources; Individual; Internet; Lead; Leadership; Legal; Logistics; Mainstreaming; Medial; Mediating; Mentors; Midwestern United States; Mind; Mission; National Institute of Allergy and Infectious Disease; Online Systems; Oral; Outcome; Peer Review; Pharmaceutical Preparations; Publications; Reagent; Recommendation; Reporting; Research Design; Research Personnel; Research Project Grants; Resource Sharing; Schedule; Scientist; Services; Site; Specific qualifier value; Students; Technology; Telephone; Time; Training; Training Activity; Travel; United States National Institutes of Health; Update; Viral; Virus; Voting; Work; antiviral drug development; drug discovery; experience; industry partner; material transfer agreement; meetings; member; new technology; novel; operation; organizational structure; outreach; pandemic disease; payment; prevent; programs; recruit; research and development; small molecule; social; symposium; virology; web site

Core A – Administration ABSTRACT The primary goals of Core A – Administration are to provide leadership, logistical support, and coordinated communication for all members and collaborators of the Midwest AViDD Center in order to expedite the successful completion of all specific aims. The PI of Core A is Reuben Harris and the Co-I is Fang Li, which mirrors the overall leadership arrangement with Dr. Harris as corresponding Co-PI and Li as Co-PI. The specific aims of Core A are to 1) provide strong and consistent leadership; 2) provide services to Program scientists, collaborators, industry partners, and Scientific Advisory Board (SAB) members; and 3) coordinate center communications including meetings, workshops, and outreach efforts. The efficient administration of this multi- institutional team is essential for the successful development of novel small molecules with potential to become orally available drugs to treat SARS-CoV-2 (all projects) and other viruses with pandemic concern (at least one other virus to be targeted by each project). Harris and Li both have experience managing multi-investigator, matrixed grants, and they meet weekly to coordinate center management. They are supported by a full-time Executive Administrative Coordinator, who provides day-to-day administrative support and coordinates meetings, workshops, travel and other communication and networking activities. The Executive Leadership Team (ExLT), which consists of Project and Core PIs, meets monthly to review the status of scientific progress and discuss administrative business including budgets. The ExLT will also receive quarterly go/no-go recommendations on hit-to-lead (H2L) advancement from the HTL Committee, which may trigger appropriate budget adjustments. Core A will also coordinate an annual workshop for all center personnel, Scientific Advisory Board (SAB) members, and Industry Partners on dates juxtaposing an anticipated pan-AViDD consortium meeting at the NIH campus. The SAB will be appointed with consultation from NIAID AViDD network leadership and will participate in the annual workshop and other meetings as required by NIAID. Additional meetings of PIs, Project personnel, Core personnel, outside collaborators, and all center-associated personnel occur on a biweekly or monthly basis as specified by each component. Web-based zoom meetings facilitate the participation of all team members regardless of geographic location.

核心 A – 管理 抽象的 核心 A – 管理的主要目标是提供领导、后勤支持和协调 中西部 AViDD 中心的所有成员和合作者之间的沟通，以加快 成功完成所有具体目标。 Core A 的 PI 是 Reuben Harris，Co-I 是 Fang Li， 反映了整体领导安排，Harris 博士担任相应的 Co-PI，Li 担任 Co-PI。具体的 核心 A 的目标是 1) 提供强有力且一致的领导力； 2）为计划科学家提供服务， 合作者、行业合作伙伴和科学顾问委员会 (SAB) 成员； 3）坐标中心 沟通，包括会议、研讨会和外展工作。这一多方面的有效管理 机构团队对于成功开发有潜力的新型小分子至关重要 用于治疗 SARS-CoV-2（所有项目）和其他引起大流行的病毒（至少一种）的口服药物 每个项目要针对的其他病毒）。 哈里斯和李都有管理多位研究者、矩阵式资助的经验，他们每周会面一次，讨论如何 协调中心管理。他们由一名全职执行行政协调员提供支持，该协调员 提供日常行政支持并协调会议、研讨会、旅行和其他 沟通和网络活动。执行领导团队 (ExLT)，由项目和 核心 PI 每月召开一次会议，审查科学进展状况并讨论行政事务，包括 预算。 ExLT 还将收到关于命中领先 (H2L) 进展的季度通过/不通过建议 HTL 委员会，这可能会引发适当的预算调整。核心A还将协调年度 为所有中心人员、科学顾问委员会 (SAB) 成员和行业合作伙伴举办的研讨会 与预期在 NIH 校园举行的泛 AViDD 联盟会议并列。 SAB 将被任命为 NIAID AViDD 网络领导层的咨询并将参加年度研讨会和其他 根据 NIAID 的要求召开会议。 PI、项目人员、核心人员、外部人员的额外会议 合作者和所有中心相关人员按照各自的规定每两周或每月进行一次 成分。基于网络的 Zoom 会议促进所有团队成员的参与，无论其地理位置如何 地点。