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Achieving Targeted Delivery of Drugs to Uterine Muscle in Women for the Prevention of Preterm Labour

Achieving Targeted Delivery of Drugs to Uterine Muscle in Women for the Prevention of Preterm Labour
实现将药物靶向输送至女性子宫肌以预防早产
批准号:
nhmrc : GNT1113847
负责人:
A/Pr Kristina Adams Waldorf
金额:
$46.9万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Development Grants
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-01-01 至 --

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英文摘要
We have patented liposomes targeted to the uterus, which enable us to deliver drugs specifically to the muscle cells of the uterus, increasing safety. The liposomes can be loaded with drugs that either block or promote contractions, creating a versatile drug delivery system that could treat premature labour or postpartum haemorrhage which are major clinical problems. We seek support to demonstrate their effectiveness in mouse and primate models of preterm labour prior to human studies.
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