Discovery to Commercialization Program for Substance Abuse Prevention and Treatment (D2C: SAPT)

药物滥用预防和治疗发现到商业化计划（D2C：SAPT）

• 批准号: 10524311
• 负责人: Kelly E Dunn
• 金额: $ 34.53万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-07-15 至 2027-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10524311
• 关键词: Active Learning; Address; Advocate; Attention; Award; Basic Science; Businesses; Caring; Certification; Clinic; Clinical; Clinical Sciences; Clinical Treatment; Communities; Complement; Custom; Diagnosis; Disabled Persons; Education; Educational Curriculum; Educational process of instructing; Educational workshop; Enrollment; Ensure; Entrepreneurship; Evaluation; Exposure to; Feedback; Fostering; Foundations; Funding; Future; Generations; Goals; Grant; Health; Individual; Instruction; Intellectual Property; Knowledge; Learning; Legal patent; Licensing; Measures; Mentors; Modeling; Participant; Pathway interactions; Patient Recruitments; Patients; Persons; Play; Positioning Attribute; Prevention; Problem Solving; Process; Professional Education; Provider; Public Health; Recruitment Activity; Research; Research Personnel; Resource Sharing; Resources; Role; Schools; Science; Scientist; Substance Use Disorder; Time; Training; Training Programs; Translations; Underrepresented Populations; Universities; Work; career; certificate program; clinical practice; commercialization; community building; design; education resources; empowered; evidence base; experience; ideation; improved; innovation; instructor; interest; meetings; next generation; online community; programs; prototype; recruit; role model; satisfaction; scaffold; service providers; skills training; stem; substance abuse prevention; substance abuse treatment; substance use treatment; synchronous contact; tool; virtual

Project Summary There has been critical underinvestment in Substance Use Disorders (SUDs) and continuing to rely on the same approaches is not working. In this proposal, we actively seek to support disruptive innovations to stem the rising tide of SUDs and stimulate progress. Such disruptions are most likely to come from those actively engaged in treating and advancing knowledge of SUDs. But many in a position to do so are not aware of or see value in discovery commercialization. Our overarching goals are to have more basic scientists think like entrepreneurs and to have access to the resources they need to engage in the commercialization processes. Through our proposed tasks, we will develop and deliver entrepreneurship education that is curated for basic science researchers, empowering them with the tools they need to commercialize their discoveries, disruptively innovate, and advance the prevention, diagnosis, and treatment of SUDs. The Discovery to Commercialization Program for Substance Abuse Prevention and Treatment (D2C: SAPT) curriculum will be systematically developed, implemented, and evaluated during this 5-year grant period. The cornerstone of the proposed initiative is a new Certificate in Entrepreneurship at the Johns Hopkins University Carey Business School (Aim 2). This program will leverage our experience in teaching entrepreneurship to scientists at Johns Hopkins and be customized to SUD researchers. The asynchronous online modules developed for the certificate program will be distributed widely (Aim 1), and through our educational efforts we will intentionally build (Aim 3) and diversify (Aim 4) the community that can support translation of discovery to market and impact SUDs. This will be a specialized program for SUD researchers aimed at scientists at all career levels that is grounded in theoretical frameworks and complemented by professional education related to entrepreneur identity formation and community building. D2C: SAPT will comprise three parts: asynchronous modules consisting of topics in ideation, market discovery, intellectual property, regulatory strategy, business, and financial modeling, an in-person multi-day workshop comprising observations in SUD clinics, conversations with stakeholders, design, and prototyping, and a mentored experiential learning component culminating in a pitch competition. Program graduates will be equipped to apply for translational funding, patents, and to license intellectual property or launch companies. More broadly, they will be part of a large virtual community of researchers and practitioners and will play a role in transforming the culture of academic scientists. With a keen understanding of the gaps that exist in the SUD field, the types of innovations that are possible, and the process needed to train scientists in moving their discoveries to market, this training program will have substantial public health impact by facilitating the launch of projects that move clinical practice in SUD to the next generation of solutions.

项目摘要 药物使用障碍（SUD）的投资不足，并继续依靠 同样的方法不起作用。在此提案中，我们积极寻求支持颠覆性创新 阻止泡沫的上升潮流并刺激进步。这种干扰最有可能来自 积极参与治疗和促进对泡沫的知识。但是许多人都不知道 在发现商业化中的价值。我们的总体目标是让更多的基本科学家认为 像企业家一样，可以访问他们从事商业化所需的资源 过程。通过我们提出的任务，我们将开发和提供经过精心策划的企业家教育 对于基础科学研究人员，使他们能够使用他们所需的工具来商业化发现的工具， 破坏创新，并提高SUD的预防，诊断和治疗。 预防药物滥用和治疗的商业化计划 （D2C：SAPT）课程将在此5年赠款中系统地开发，实施和评估 时期。拟议倡议的基石是约翰斯的新企业家证书 霍普金斯大学凯里商学院（AIM 2）。该计划将利用我们在教学方面的经验 约翰·霍普金斯（Johns Hopkins）的科学家企业家精神，并向SUD研究人员定制。异步 为证书计划开发的在线模块将被广泛分发（AIM 1），并通过我们的 教育努力我们将有意建立（目标3）并多样化（目标4）可以支持的社区 将发现向市场和影响SUD的翻译。 这将是针对SUD研究人员的专业计划，针对所有职业水平的科学家 基于理论框架，并接受与企业家有关的专业教育 身份形成和社区建设。 D2C：SAPT将包括三个部分：异步模块 包括构想，市场发现，知识产权，监管策略，业务和 财务建模，一个面对面的多日研讨会，包括在SUD诊所进行观察，对话 利益相关者，设计和原型制作，以及指导的体验学习组成部分最终 球场比赛。课程毕业生将有能力申请翻译资金，专利和许可 知识产权或成立公司。更广泛地说，它们将成为大型虚拟社区的一部分 研究人员和从业人员将在改变学术科学家的文化中发挥作用。与 敏锐地了解SUD领域中存在的差距，可能的创新类型以及 需要培训科学家将其发现转移到市场所需的过程，该培训计划将具有 通过促进将SUD临床实践推动的项目推出的实质性公共卫生影响很大 下一代解决方案。