Applying Item Response Theory to Improve Patient Reported Outcome Use in Dermatology Clinical Practice

应用项目反应理论改善皮肤科临床实践中患者报告的结果使用

• 批准号: 10524835
• 负责人: John Barbieri
• 金额: $ 17.39万
• 依托单位: BRIGHAM AND WOMEN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-07-01 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10524835
• 关键词: Acne; Address; Advisory Committees; Affect; Area; Atopic Dermatitis; Award; Calibration; Caring; Client satisfaction; Clinic; Clinical; Clinical Research; Computers; Cost effectiveness research; Data; Dermatology; Development; Development Plans; Disease; Disease Outcome; Electronic Health Record; Environment; Faculty; Focus Groups; Foundations; Goals; Health Services Research; Health system; Healthcare; Hospitals; Individual; Information Systems; Knowledge; Learning; Measurement; Measures; Mentored Patient-Oriented Research Career Development Award; Mentors; Methods; Modernization; Nature; Outcome; Outcome Measure; Outcomes and Health Services Research; Patient Care; Patient Outcomes Assessments; Patient-Focused Outcomes; Patients; Personal Satisfaction; Persons; Physical Function; Physicians; Positioning Attribute; Property; Psoriasis; Psychometrics; Pus; Qualitative Research; Quality of Care; Quality of life; Reporting; Research; Resources; Review Literature; Scientist; Selection for Treatments; Severity of illness; Skin; Supervision; Surveys; Symptoms; Techniques; Testing; Time; Training; United States; Validation; Visit; Woman; Work; base; care outcomes; career; career development; chronic inflammatory skin; clinical care; clinical practice; comparative cost effectiveness; concept mapping; economic cost; emotional functioning; experience; field study; improved; indexing; innovation; insight; instrument; knowledge base; member; novel; patient oriented; psychosocial; research and development; response; skills; skin disorder; sound; symptom management; teledermatology; tenure track; theories; treatment response

Project Summary/Abstract Research: While effective measurement of the patient’s perspective on their illness and its treatment provides complimentary information to objective disease severity, patient-reported outcomes capturing the lived experience of chronic inflammatory skin disease are rarely used in routine dermatology practice. Item response theory techniques can enable more efficient administration of patient-reported outcomes in the clinic, which can address barriers such as time to administer these measures. The purpose of this study is to 1. prioritize the outcome domains that are most meaningful to individuals with chronic inflammatory skin diseases such as acne, psoriasis, and atopic dermatitis; 2. evaluate the content validity of a novel Patient-Reported Outcomes Measurement Information System (PROMIS) profile measuring these domains; 3. field test and evaluate the validity of a novel PROMIS profile to capture the lived experience of chronic inflammatory skin disease. The overall objectives of this K23 award proposal are to improve the care of patients with chronic inflammatory skin diseases by developing a practical patient-reported outcome to measure the lived experience of these skin diseases, which will enable increased use of patient-reported outcomes in routine clinical care. Candidate: Dr. Barbieri’s long-term career goal is to become an independent, patient-oriented physician- scientist, with a focus on chronic inflammatory skin diseases, patient-reported outcomes, and health services research. His prior training has provided him with a foundational background in these areas. Environment: During the award period Dr. Barbieri will devote 80% of his time to clinical research and 20% to the clinical care of patients with chronic inflammatory skin disease such as acne, atopic dermatitis, and psoriasis. Dr. Margolis and Dr. Pusic, the candidate’s primary mentors, have directly supervised the training of numerous successful junior faculty members and Dr. Barbieri will benefit from his experience and enthusiasm for cultivating the careers of junior scientists. The Brigham and Women’s Hospital offers a rich training environment, including resources and expertise available in the Clinical Unit for Research Innovation and Trials (CUReIT) and Patient-Reported Outcomes, Value & Experience (PROVE) Center. Combined with the knowledge and expertise available in the Department of Dermatology and in Dr. Margolis’s and Dr. Pusic’s labs, these opportunities will provide an unparalleled opportunity to begin a career as a physician scientist. Career Development: With the support of his advisory committee, Dr. Barbieri’s training will focus on advanced psychometric techniques and qualitative research to develop a strong knowledge base with respect to patient-reported outcome development and validation. Completion of the proposed research and career development plan will give Dr. Barbieri the knowledge and skills to achieve scientific independence, transition to a tenure track faculty position, and build a strong foundation for a career in patient-oriented clinical research.

项目总结/摘要 研究：虽然有效测量患者对疾病及其治疗的看法提供了 客观疾病严重程度的补充信息，患者报告的结果捕获了 慢性炎症性皮肤病的经验很少用于常规皮肤病学实践。项目反应 理论技术可以在临床上更有效地管理患者报告的结果， 可以解决诸如执行这些措施的时间等障碍。本研究的目的是1.优先考虑 对慢性炎症性皮肤病患者最有意义的结果领域， 痤疮、牛皮癣和特应性皮炎; 2.评价新型患者报告结局的内容效度 测量信息系统（PROMIS）的配置文件测量这些领域; 3。现场测试和评估 一种新的PROMIS概况的有效性，以捕捉慢性炎症性皮肤病的生活经验。的 K23奖项的总体目标是改善慢性炎症皮肤患者的护理 通过开发一个实际的患者报告的结果来衡量这些皮肤的生活经验， 疾病，这将使更多的使用患者报告的结果在常规临床护理。 候选人：Barbieri博士的长期职业目标是成为一名独立的，以病人为导向的医生- 科学家，专注于慢性炎症性皮肤病，患者报告的结果和卫生服务 research.他之前的培训为他提供了这些领域的基础背景。 环境：在获奖期间，Barbieri博士将把80%的时间用于临床研究，20%用于 慢性炎症性皮肤病如痤疮、特应性皮炎和 银屑病马戈利斯博士和Pusic博士，候选人的主要导师，直接监督培训， 许多成功的年轻教师和Barbieri博士将受益于他的经验和热情 来培养年轻科学家的事业布里格姆妇女医院提供丰富的培训 环境，包括临床研究创新和试验部门提供的资源和专业知识 （CUREIT）和患者报告的结果，价值和经验（PROVE）中心。结合 皮肤科以及Margolis博士和Pusic博士的知识和专业知识 实验室，这些机会将提供一个无与伦比的机会，开始职业生涯作为一个医生科学家。 职业发展：在他的顾问委员会的支持下，Barbieri博士的培训将侧重于 先进的心理测量技术和定性研究，以建立一个强大的知识基础， 患者报告的结果开发和验证。完成拟议的研究和职业生涯 发展计划将为Barbieri博士提供知识和技能，以实现科学独立， 终身教职，并为以患者为导向的临床研究事业奠定坚实的基础。