SUPPLEMENT- Using design thinking approaches to tailor a dyadic behavioral sleep intervention for persons living with dementia and their caregivers

补充-使用设计思维方法为痴呆症患者及其护理人员量身定制二元行为睡眠干预措施

• 批准号: 10535237
• 负责人: Glenna Shemida Brewster
• 金额: $ 5.4万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-01 至 2026-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10535237
• 关键词: Affect; Alzheimer' s disease related dementia; Behavior Therapy; Behavioral; Caregiver research; Caregivers; Clinical Trials; Cognitive Therapy; Dementia; Dementia caregivers; Development; Diagnosis; Disease; Foundations; Future; Goals; Health; Health Personnel; Human; Individual; Intervention; Intervention Trial; Interview; K-Series Research Career Programs; Knowledge; Manuscripts; Mentored Patient-Oriented Research Career Development Award; Mentors; Methods; National Institute on Aging; Oral; Outcome; Peer Review; Persons; Phase; Population; Prevalence; Process; Public Health; Quality of life; Randomized Controlled Trials; Research; Research Project Grants; Sleep; Sleep disturbances; Sleeplessness; Structure; Testing; Thinking; Training; Waiting Lists; Writing; analytical method; behavioral/social science; caregiving; dementia caregiving; depressive symptoms; design; improved; innovation; member; mild cognitive impairment; novel; patient oriented; programs; skills; social neuroscience; theories

PROJECT SUMMARY Sleep disturbance is prevalent in persons living with mild cognitive impairment or early-stage Alzheimer’s disease and related dementias (PLwCI) as well as their caregivers. This prevalence suggests that sleep disturbance is an interdependent process that synergistically affects both members of the caregiving dyad. Sleep disturbance is associated with poorer health outcomes, including higher depressive symptoms and lower quality of life. Cognitive behavioral therapy for insomnia (CBTi) is effective for improving sleep disturbance in many populations, and support from a partner during CBTi results in more successful outcomes. The interdependence of PLwCI-caregiver sleep disturbance suggests the need for a dyadic intervention. However, there are no structured fully dyadic interventions focused on managing sleep disturbance in PLwCI and their caregivers; moreover, no dyadic interventions have been developed with input from these stakeholders. Aligned with the National Institute of Aging’s Behavioral and Social Science and Neuroscience high-priority dementia caregiver research agenda, the proposed K23 Patient-Oriented Mentored Career Development Award seeks to use design thinking, human-centered approaches within the CBTi framework to tailor a dyadic intervention for PLwCI and their caregivers. Twenty PLwCI-caregiver dyads and 10 healthcare providers will be interviewed during the tailoring phase. We will then conduct a waitlist randomized control trial (N = 40 dyads) to test the acceptability, feasibility, and preliminary immediate and sustained efficacy (3 months) of the dyadic intervention. The completion of this mentored research project will enable me to acquire foundational knowledge for conducting large-scale intervention trials and fulfill the need for effective dyadic interventions to treat sleep disturbance in PLwCI and caregiver dyads. The interdisciplinary training plan and goals developed for this K23 award will fill a critical gap in my current skill set. Building on my training as a clinician with expertise in sleep and dementia caregiving, I will develop proficiency in 1) design thinking approaches, 2) dyadic theories, concepts, and analytic methods, 3) identification and diagnosis of dementia-related disorders, including a focus on how these disorders relate to sleep disturbance, and 4) scientific writing, oral presentations, manuscript development, and peer review. I have assembled an excellent team of mentors (Drs. Hepburn, Barton, Lyons and Lah) and a collaborator (Dr. Gehrman). The K23 award will provide me with the necessary foundation to build a successful and independent program of research related to sleep, dementia, and caregiving.

项目总结