Use of Digital Phenotyping to Understand Digital Media Influence on Adolescent Substance Use

项目摘要 这位候选人正在请求支持一项为期四年的使用数字技术的培训和研究计划 表型分析，以获得对数字媒体如何影响药物和酒精暴露等方面的新理解- 网上的相关内容会影响青少年药物的采购和使用。解决青少年问题 物质使用具有挑战性，因为各种社会和环境因素可能会影响年轻人的 决定用毒品或酒精做实验。数字媒体使用，包括在线接触与物质有关的内容 内容，是这样一个潜在的因素，在青少年生活中日益增长的日常影响。然而，目前几乎没有 了解不同媒体平台对毒品和酒精相关内容的暴露如何不同(例如，游戏， 社交媒体)，也不知道在一个媒体平台上曝光是否更有可能促进药品采购 或者催生物质使用的例子。我们对这些关系的理解的局限性是 其次是回忆偏差和先前研究中使用的横断面调查方法。这个项目 将利用新的数字表型(DP)技术收集智能手机传感器数据 关于数字媒体曝光和物质使用的积极调查。通过这种方式，我们计划确定更多 准确地说，那些影响青少年吸毒和酗酒的数字媒体曝光和经历， 并相应地改进现有的临床指导。在拟议的培训计划中，候选人将建立 根据她以前使用数字表型来理解高危青少年数字媒体的经验 使用。她的培训计划包括：1)多变量纵向分析的统计方法，2)设计 以及实施数字表型工具，以真实捕捉高风险的数字体验/曝光 时间，3)生态瞬时干预方案的设计和试点，4)负责任的行为 有药物使用史的青少年的数字表型研究。 与NIDA确定物质使用的行为、环境和社会原因的使命一致 在整个生命周期中，这项研究计划将1)确定数字媒体使用的哪些子类型更多 经常与接触毒品和酒精相关的内容有关，以及2)评估哪些暴露是 更多地与物质采购和使用有关。我们还将探索 精神症状和网络受害对心理健康关系的潜在调节作用 接触与物质相关的内容和物质使用。这项研究将在两年内进行 受试者年龄在15至18岁之间。随后的R01提案将概述以下设计和试点 一种以数字实时干预为目标的生态瞬时干预协议 与青少年药物使用有关的暴露/经历。

Project Summary This candidate is requesting support for a four-year program of training and research to use digital phenotyping to gain a novel understanding of how digital media influences like exposure to drug and alcohol- related content online can impact adolescent substance procurement and use. Addressing adolescent substance use is challenging due to the diverse social and environmental factors that can impact a youth’s decision to experiment with drugs or alcohol. Digital media use, including online exposure to substance-related content, is one such potential factor of growing daily influence in adolescent lives. However, little is currently known about how exposure to drug and alcohol-related content differs across media platforms (e.g. gaming, social media), nor whether exposure on one media platform may be more likely to facilitate drug procurement or precipitate an instance of substance use. This limitation in our understanding of these relationships is secondary to both recall bias and the cross-sectional survey methodology used in prior studies. This project will leverage novel digital phenotyping (DP) technology to collect smartphone sensor data in combination with active surveys about digital media exposures and substance use. In this manner, we plan to identify more accurately those digital media exposures and experiences that impact adolescent use of drugs and alcohol, and improve upon existing clinical guidance accordingly. In the proposed training plan, the candidate will build upon her previous experience in use of digital phenotyping to understand high-risk adolescent digital media use. Her training plan includes training in: 1) statistical methods for multivariate longitudinal analysis, 2) design and implementation of digital phenotyping tools that capture high-risk digital experiences/exposures in real time, 3) design and piloting of ecological momentary intervention protocols, and 4) responsible conduct of digital phenotyping research in adolescents with a history of substance use. In line with NIDA’s mission of identifying behavioral, environmental and social causes of substance use across the lifespan, this research plan will 1) determine which subtypes of digital media use are more frequently associated with exposure to drug and alcohol-related content and 2) assess which exposures are more frequently associated with instances of substance procurement and use. We will also explore the potential moderating effects of psychiatric symptoms and online victimization on the relationship between exposure to substance-related content and substance use. This study will be performed across 2 years in subjects between 15 and 18 years of age. A subsequent R01 proposal will then outline the design and pilot of an ecological momentary intervention protocol with the goal of intervening in real time upon digital exposures/experiences associated with adolescent substance use.