Understanding the Associations between Romantic Relationship Conflict, Psychophysiological Responding and Alcohol Misuse among Emerging Adults

项目概要/摘要 拟议的K23指导以患者为导向的研究职业发展奖将提供 申请人必须经过必要的培训和实践经验，以成功地过渡到独立的酒精 research.霍根博士将学习酒精管理研究和心理生理数据的复杂性 收集，同时获得经验的新兴成人的研究。成年期（EA）是一种发展性的 阶段的特点是增加冒险行为，包括重度间歇性饮酒（HED）。虽然 酒精滥用在这个阶段是正常的，HED与负面的短期和长期后果有关。 浪漫关系中的冲突可能是EA饮酒行为中特别突出的社会影响，但很少 在这一人群中，浪漫伴侣和关系功能在HED中的作用是已知的。拟议 这项研究解决了文献中的这一关键空白。EA夫妇将从事两个冲突解决任务 穿插两次酒精给药程序。由于高频心率变异性（HF-HRV） 与压力体验中的酒精使用和情绪调节有关，HF-HRV和其他 将在整个实验室程序中收集生理数据。候选人已经召集了一个 专家导师团队谁是完美的定位，以实现培训目标和研究目标，在这一领域 应用程序.朱丽安·弗拉纳根（Julianne Flanagan）博士，主要导师，是关系功能和AUD研究的专家 和AUD临床试验。詹姆斯·墨菲博士将提供酒精研究的指导， 新兴的成年人口和博士詹妮弗巴克曼将提供心理生理学和酒精的导师 在成年人中使用。最后，多米尼克帕罗特博士将咨询实施二元酒精 管理程序和登记不同的夫妇。拟议的K23裁决将提供受保护的 研究时间、专家指导和培训机会，以实现以下培训目标：（1） 成为精通酒精管理研究范式的行为，（2）扩大和完善我的 心理生理学研究技能，（3）获得酒精预防文献和当前预防的基础 方法之间的EA，（4）扩大我的定量技能，（5）增加我的学术生产力和赠款 写作技巧拟议中的K23奖将是霍根博士过渡到成为一名 生产，独立的酒精研究人员在关键的公共卫生优先领域的专业知识。

PROJECT SUMMARY/ABSTRACT The proposed K23 Mentored Patient-Oriented Research Career Development Award will provide the applicant with necessary training and hands-on experience to successfully transition to independence in alcohol research. Dr. Hogan will learn the intricacies of alcohol administration studies and psychophysiological data collection while gaining experience in the study of emerging adults. Emerging adulthood (EA) is a developmental phase characterized by increased risk-taking behaviors, including heavy episodic drinking (HED). Although alcohol misuse is normative at this stage, HED is associated with negative short- and long-term consequences. Conflict in romantic relationships may be a particularly salient social influence in EA drinking behavior, but little is known about the role of romantic partners and relationship functioning in HED in this population. The proposed study addresses this critical gap in the literature. EA couples will engage in two conflict resolution tasks interspersed with two alcohol administration procedures. Because high frequency heart rate variability (HF-HRV) is associated with alcohol use and emotion regulation during stressful experiences, HF-HRV and other physiological data will be collected throughout the laboratory procedures. The candidate has assembled an expert mentorship team who are perfectly positioned to achieve the training goals and research aims within this application. Dr. Julianne Flanagan, primary mentor, is an expert in the study of relationship functioning and AUD and AUD clinical trials among couples. Dr. James Murphy will provide mentorship on alcohol studies with an emerging adult population and Dr. Jennifer Buckman will provide mentorship on psychophysiology and alcohol use among emerging adults. Finally, Dr. Dominic Parrott will consult on the implementation of dyadic alcohol administration procedures and enrollment of diverse couples. The proposed K23 award will provide the protected research time, expert mentorship, and training opportunities to accomplish the following training goals: (1) become proficient in the conduct of alcohol administration research paradigms, (2) expand and refine my psychophysiological research skills, (3) gain a foundation in alcohol prevention literature and current prevention approaches among EA, (4) extend my quantitative skills, and (5) increase my scholarly productivity and grant writing skills. The proposed K23 award will be an invaluable asset in Dr. Hogan’s transition to becoming a productive, independent alcohol researcher with expertise in critical public health priority areas.