Training in Cardiovascular Research

心血管研究培训

• 批准号: 10663074
• 负责人: JOSEPH A HILL
• 金额: $ 54.23万
• 依托单位: UT SOUTHWESTERN MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-07-01 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10663074
• 关键词: Cardiovascular system; Research; Training

Project Summary The T32-funded Cardiovascular Training Program at UT Southwestern has a long and illustrious history of fostering emergence of capable and productive investigators ideally positioned for independence and success. Indeed, our Program has an impressive track record, producing a large number of capable researchers who continue to have substantial impact. Over this period, our institution and the Division of Cardiology have evolved from a research emphasis heavily weighted towards basic science to one that now includes broad strength and representation in translational science, clinical trials, population-based research, and health services and outcomes research. Four years ago, we completely revamped our T32 Training Program, shrinking its size, limiting it to postdoctoral trainees, sharpening the focus of our oversight and management, and becoming more “data driven” in evaluating our trainees and our Program. Now, 4 years later, we can say that the transition has been a huge success. Our trainees are now uncommonly productive in their research endeavors. The program is evenly balanced between basic and clinical/translational research. Our program is now reflective of a) the growth of highly successful programs in clinical and translational cardiovascular research at UT Southwestern over the past decade, b) our goal to prepare the best investigators across the full spectrum of cardiovascular research, and c) the reality of the current funding environment for basic research. Importantly, this shift in focus allowed us to better recruit MD investigators who are co-enrolled in clinical training programs. Of note, the Internal Medicine Residency and Cardiology Fellowships at UT Southwestern are among the strongest in the country. Our Cardiovascular Training Program is just that, a training program, and not a funding mechanism. Our primary objective is to develop the next generation of transformative cardiovascular investigators by recruiting highly talented and motivated individuals and preparing them for success in an increasingly competitive and resource-challenged environment. A secondary objective is to expand the cadre of women and minorities pursuing careers in cardiovascular research. Our faculty is diverse, spanning a spectrum of expertise from molecule to cell, organ system, organism, and population. Members of our faculty are distributed across the full spectrum of faculty rank, gender, and ethnic background. In summary, our Program is designed to foster the emergence of the next generation of investigators, teachers, and mentors at a time when the need for such has never been greater.

项目摘要 UT Southwestern的T32资助的心血管训练计划有悠久而杰出的历史 促进有能力和产品调查人员的出现，理想地定位了独立性和成功。 确实，我们的计划具有令人印象深刻的记录，产生了许多能干的研究人员 继续产生重大影响。在此期间，我们的机构和心脏病学已经发展 从一项重点重视基础科学的研究到现在包括广泛的力量和 转化科学，临床试验，基于人群的研究和卫生服务的代表性以及 结果研究。 四年前，我们完全修改了T32培训计划，使其尺寸缩小，将其限制为 博士后学员，提高了我们的监督和管理的重点，并成为更多的“数据驱动” 评估我们的培训和计划。 现在，四年后，我们可以说过渡取得了巨大的成功。我们的学员现在 他们的研究努力毫不奇怪。该程序甚至在基本和 临床/翻译研究。我们的计划现在反映了a）在 在过去的十年中，UT西南部的临床和翻译心血管研究，b）我们的目标 在整个心血管研究中准备最佳研究人员，c）当前的现实 基础研究的资助环境。重要的是，这种重点转变使我们能够更好地招募MD 在临床培训计划中共同入围的调查人员。值得注意的是，内科医学居住和 UT西南部的心脏病学奖学金是该国最强的。 我们的心血管培训计划就是培训计划，而不是一种资金机制。我们的 主要目的是通过招募来开发下一代变革性心血管调查员 高度才华和成熟的个人，并为他们的成功做好准备，以竞争日益激烈 资源挑战的环境。次要目标是扩大妇女和少数民族的干部 从事心血管研究的职业。我们的教师有分歧，跨越了一系列专业知识 细胞，生物体，生物体和种群的分子。我们教师的成员分配了 教师等级，性别和种族背景的范围。 总而言之，我们的计划旨在促进下一代研究人员的出现， 老师和指导者在需要的时候从未如此大。

项目成果

Mediators of ertugliflozin effects on heart failure and kidney outcomes among patients with type 2 diabetes mellitus.

• DOI: 10.1111/dom.14769
• 发表时间: 2022-09
• 期刊: Diabetes, obesity & metabolism

Sex and Race Differences in the Utilization and Outcomes of Coronary Artery Bypass Grafting Among Medicare Beneficiaries, 1999-2014.

• DOI: 10.1161/jaha.118.009014
• 发表时间: 2018-07-12
• 期刊: Journal of the American Heart Association
• 影响因子: 5.4
• 作者: Angraal S;Khera R;Wang Y;Lu Y;Jean R;Dreyer RP;Geirsson A;Desai NR;Krumholz HM
• 通讯作者: Krumholz HM

Hospital Variation in Time to Epinephrine for Nonshockable In-Hospital Cardiac Arrest.

• DOI: 10.1161/circulationaha.116.025459
• 发表时间: 2016-12-20
• 期刊: Circulation
• 影响因子: 37.8
• 作者: Khera R;Chan PS;Donnino M;Girotra S;American Heart Association’s Get With The Guidelines-Resuscitation Investigators
• 通讯作者: American Heart Association’s Get With The Guidelines-Resuscitation Investigators

Chemoprevention of colorectal cancer in individuals with previous colorectal neoplasia: systematic review and network meta-analysis.

• DOI: 10.1136/bmj.i6188
• 发表时间: 2016-12-05
• 期刊: BMJ (Clinical research ed.)
• 作者: Dulai PS;Singh S;Marquez E;Khera R;Prokop LJ;Limburg PJ;Gupta S;Murad MH
• 通讯作者: Murad MH

Gaps in Guideline-Based Lipid-Lowering Therapy for Secondary Prevention in the United States: A Retrospective Cohort Study of 322 153 Patients.

美国二级预防中基于指南的降脂治疗的差距：一项针对 322-153 名患者的回顾性队列研究。

• DOI: 10.1161/circoutcomes.122.009787
• 发表时间: 2023
• 期刊: Circulation. Cardiovascular quality and outcomes
• 作者: Navar,AnnMarie;Kolkailah,AhmedA;Gupta,Anand;Gillard,KristinKhalaf;Israel,MarcK;Wang,Yiqing;Peterson,EricD
• 通讯作者: Peterson,EricD