Training in Cardiovascular Research

心血管研究培训

• 批准号: 10663074
• 负责人: JOSEPH A HILL
• 金额: $ 54.23万
• 依托单位: UT SOUTHWESTERN MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-07-01 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10663074
• 关键词: Cardiovascular system; Research; Training

Project Summary The T32-funded Cardiovascular Training Program at UT Southwestern has a long and illustrious history of fostering emergence of capable and productive investigators ideally positioned for independence and success. Indeed, our Program has an impressive track record, producing a large number of capable researchers who continue to have substantial impact. Over this period, our institution and the Division of Cardiology have evolved from a research emphasis heavily weighted towards basic science to one that now includes broad strength and representation in translational science, clinical trials, population-based research, and health services and outcomes research. Four years ago, we completely revamped our T32 Training Program, shrinking its size, limiting it to postdoctoral trainees, sharpening the focus of our oversight and management, and becoming more “data driven” in evaluating our trainees and our Program. Now, 4 years later, we can say that the transition has been a huge success. Our trainees are now uncommonly productive in their research endeavors. The program is evenly balanced between basic and clinical/translational research. Our program is now reflective of a) the growth of highly successful programs in clinical and translational cardiovascular research at UT Southwestern over the past decade, b) our goal to prepare the best investigators across the full spectrum of cardiovascular research, and c) the reality of the current funding environment for basic research. Importantly, this shift in focus allowed us to better recruit MD investigators who are co-enrolled in clinical training programs. Of note, the Internal Medicine Residency and Cardiology Fellowships at UT Southwestern are among the strongest in the country. Our Cardiovascular Training Program is just that, a training program, and not a funding mechanism. Our primary objective is to develop the next generation of transformative cardiovascular investigators by recruiting highly talented and motivated individuals and preparing them for success in an increasingly competitive and resource-challenged environment. A secondary objective is to expand the cadre of women and minorities pursuing careers in cardiovascular research. Our faculty is diverse, spanning a spectrum of expertise from molecule to cell, organ system, organism, and population. Members of our faculty are distributed across the full spectrum of faculty rank, gender, and ethnic background. In summary, our Program is designed to foster the emergence of the next generation of investigators, teachers, and mentors at a time when the need for such has never been greater.

项目摘要 UT西南大学的T32资助的心血管训练计划有着悠久而辉煌的历史。 培养有能力和富有成效的调查人员的出现，使他们能够独立和成功。 事实上，我们的计划有一个令人印象深刻的记录，产生了大量有能力的研究人员， 继续产生重大影响。在此期间，我们的机构和心脏病学部门已经发展 从一个研究重点严重偏重于基础科学，现在包括广泛的力量， 在转化科学、临床试验、基于人口的研究和卫生服务方面的代表性， 成果研究。 四年前，我们彻底修改了我们的T32培训计划，缩小了规模，将其限制在 博士后学员，加强我们的监督和管理的重点，并成为更多的“数据驱动” 评估我们的学员和项目 四年后的今天，我们可以说转型取得了巨大成功。我们的学员现在 在他们的研究工作中异常富有成效。该计划是均衡之间的基本和 临床/转化研究。我们的计划现在反映了a）在全球范围内非常成功的计划的增长， 在过去的十年中，UT西南大学的临床和转化心血管研究，B）我们的目标是 准备最好的研究人员在整个频谱的心血管研究，和c）的现实，目前 基础研究的资金环境。重要的是，这种重点的转变使我们能够更好地招募MD 共同参加临床培训项目的研究者。值得注意的是，内科住院医师和 UT西南大学的心脏病学奖学金是全国最强的。 我们的心血管训练计划只是一个训练计划，而不是一个资助机制。我们 主要目标是通过招募新一代变革性心血管研究者， 高度有才华和积极性的个人，并为他们在日益激烈的竞争中取得成功做好准备， 资源挑战的环境。第二个目标是扩大妇女和少数民族干部队伍 从事心血管研究我们的教师是多样化的，跨越专业知识的范围，从 分子到细胞、器官系统、生物体和群体。我们的教师分布在整个 教师等级，性别和种族背景的光谱。 总之，我们的计划旨在促进下一代调查员的出现， 教师和导师的时候，需要这样的从来没有更大。

项目成果

Mediators of ertugliflozin effects on heart failure and kidney outcomes among patients with type 2 diabetes mellitus.

• DOI: 10.1111/dom.14769
• 发表时间: 2022-09
• 期刊: Diabetes, obesity & metabolism

Sex and Race Differences in the Utilization and Outcomes of Coronary Artery Bypass Grafting Among Medicare Beneficiaries, 1999-2014.

• DOI: 10.1161/jaha.118.009014
• 发表时间: 2018-07-12
• 期刊: Journal of the American Heart Association
• 影响因子: 5.4
• 作者: Angraal S;Khera R;Wang Y;Lu Y;Jean R;Dreyer RP;Geirsson A;Desai NR;Krumholz HM
• 通讯作者: Krumholz HM

Hospital Variation in Time to Epinephrine for Nonshockable In-Hospital Cardiac Arrest.

• DOI: 10.1161/circulationaha.116.025459
• 发表时间: 2016-12-20
• 期刊: Circulation
• 影响因子: 37.8
• 作者: Khera R;Chan PS;Donnino M;Girotra S;American Heart Association’s Get With The Guidelines-Resuscitation Investigators
• 通讯作者: American Heart Association’s Get With The Guidelines-Resuscitation Investigators

Chemoprevention of colorectal cancer in individuals with previous colorectal neoplasia: systematic review and network meta-analysis.

• DOI: 10.1136/bmj.i6188
• 发表时间: 2016-12-05
• 期刊: BMJ (Clinical research ed.)
• 作者: Dulai PS;Singh S;Marquez E;Khera R;Prokop LJ;Limburg PJ;Gupta S;Murad MH
• 通讯作者: Murad MH

Interpreting Absolute and Relative Risk Reduction in the Context of Recent Cardiovascular Outcome Trials in Patients with Type 2 Diabetes.

解释近期 2 型糖尿病患者心血管结果试验中绝对和相对风险降低的情况。

• DOI: 10.1007/s11892-021-01417-0
• 发表时间: 2021
• 期刊: Current diabetes reports
• 影响因子: 4.2
• 作者: Berg,DavidD;Kolkailah,AhmedA;Sarraju,Ashish;Kerchberger,AnneMarie;Eljalby,Mahmoud;McGuire,DarrenK
• 通讯作者: McGuire,DarrenK