Training in Cardiovascular Research

心血管研究培训

• 批准号: 10663074
• 负责人: JOSEPH A HILL
• 金额: $ 54.23万
• 依托单位: UT SOUTHWESTERN MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-07-01 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10663074
• 关键词: Cardiovascular system; Research; Training

Project Summary The T32-funded Cardiovascular Training Program at UT Southwestern has a long and illustrious history of fostering emergence of capable and productive investigators ideally positioned for independence and success. Indeed, our Program has an impressive track record, producing a large number of capable researchers who continue to have substantial impact. Over this period, our institution and the Division of Cardiology have evolved from a research emphasis heavily weighted towards basic science to one that now includes broad strength and representation in translational science, clinical trials, population-based research, and health services and outcomes research. Four years ago, we completely revamped our T32 Training Program, shrinking its size, limiting it to postdoctoral trainees, sharpening the focus of our oversight and management, and becoming more “data driven” in evaluating our trainees and our Program. Now, 4 years later, we can say that the transition has been a huge success. Our trainees are now uncommonly productive in their research endeavors. The program is evenly balanced between basic and clinical/translational research. Our program is now reflective of a) the growth of highly successful programs in clinical and translational cardiovascular research at UT Southwestern over the past decade, b) our goal to prepare the best investigators across the full spectrum of cardiovascular research, and c) the reality of the current funding environment for basic research. Importantly, this shift in focus allowed us to better recruit MD investigators who are co-enrolled in clinical training programs. Of note, the Internal Medicine Residency and Cardiology Fellowships at UT Southwestern are among the strongest in the country. Our Cardiovascular Training Program is just that, a training program, and not a funding mechanism. Our primary objective is to develop the next generation of transformative cardiovascular investigators by recruiting highly talented and motivated individuals and preparing them for success in an increasingly competitive and resource-challenged environment. A secondary objective is to expand the cadre of women and minorities pursuing careers in cardiovascular research. Our faculty is diverse, spanning a spectrum of expertise from molecule to cell, organ system, organism, and population. Members of our faculty are distributed across the full spectrum of faculty rank, gender, and ethnic background. In summary, our Program is designed to foster the emergence of the next generation of investigators, teachers, and mentors at a time when the need for such has never been greater.

项目摘要 德克萨斯大学西南分校T32资助的心血管培训项目有着悠久而辉煌的历史 培养有能力和富有成效的调查员的出现，这是独立和成功的理想条件。 事实上，我们的计划有着令人印象深刻的记录，培养了一大批有能力的研究人员，他们 继续产生实质性影响。在这段时间里，我们的机构和心脏病科发生了变化 从偏重于基础科学的研究重点，到现在包括广泛实力和 在转化科学、临床试验、基于人群的研究和卫生服务中的代表性以及 结果研究。 四年前，我们彻底修改了T32培训计划，缩小了规模，将其限制在 博士后实习生，强化我们监督和管理的重点，变得更加“数据驱动” 在评估我们的学员和我们的计划时。 现在，4年过去了，我们可以说，过渡取得了巨大的成功。我们的实习生现在 在他们的研究工作中取得了非同寻常的成果。该计划在基本计划和基本计划之间保持平衡 临床/转化性研究。我们的计划现在反映了a)非常成功的计划在 德州大学西南分校过去十年的临床和转化性心血管研究，b)我们的目标是 准备最好的心血管研究人员，以及c)当前的现实 为基础研究提供资金环境。重要的是，这种重点的转移使我们能够更好地招聘MD 参与临床培训计划的研究人员。值得注意的是，内科住院医师和 德克萨斯大学西南分校的心脏病学奖学金在全国名列前茅。 我们的心血管训练计划只是一个训练计划，而不是一种资助机制。我们的 主要目标是通过招募新一代变革性心血管研究人员 非常有才华和上进心的人，并为他们在竞争日益激烈和 资源紧缺的环境。次要目标是扩大妇女和少数民族干部队伍。 追求心血管研究方面的职业。我们的教员是多样化的，涵盖了以下领域的专业知识 分子到细胞、器官系统、有机体和种群。我们的教职员工分布在 教员级别、性别和种族背景的范围。 总而言之，我们的计划旨在促进下一代调查人员的出现， 在对教师和导师的需求从未如此强烈的时候。

项目成果

Mediators of ertugliflozin effects on heart failure and kidney outcomes among patients with type 2 diabetes mellitus.

• DOI: 10.1111/dom.14769
• 发表时间: 2022-09
• 期刊: Diabetes, obesity & metabolism

Sex and Race Differences in the Utilization and Outcomes of Coronary Artery Bypass Grafting Among Medicare Beneficiaries, 1999-2014.

• DOI: 10.1161/jaha.118.009014
• 发表时间: 2018-07-12
• 期刊: Journal of the American Heart Association
• 影响因子: 5.4
• 作者: Angraal S;Khera R;Wang Y;Lu Y;Jean R;Dreyer RP;Geirsson A;Desai NR;Krumholz HM
• 通讯作者: Krumholz HM

Hospital Variation in Time to Epinephrine for Nonshockable In-Hospital Cardiac Arrest.

• DOI: 10.1161/circulationaha.116.025459
• 发表时间: 2016-12-20
• 期刊: Circulation
• 影响因子: 37.8
• 作者: Khera R;Chan PS;Donnino M;Girotra S;American Heart Association’s Get With The Guidelines-Resuscitation Investigators
• 通讯作者: American Heart Association’s Get With The Guidelines-Resuscitation Investigators

Chemoprevention of colorectal cancer in individuals with previous colorectal neoplasia: systematic review and network meta-analysis.

• DOI: 10.1136/bmj.i6188
• 发表时间: 2016-12-05
• 期刊: BMJ (Clinical research ed.)
• 作者: Dulai PS;Singh S;Marquez E;Khera R;Prokop LJ;Limburg PJ;Gupta S;Murad MH
• 通讯作者: Murad MH

Interpreting Absolute and Relative Risk Reduction in the Context of Recent Cardiovascular Outcome Trials in Patients with Type 2 Diabetes.

解释近期 2 型糖尿病患者心血管结果试验中绝对和相对风险降低的情况。

• DOI: 10.1007/s11892-021-01417-0
• 发表时间: 2021
• 期刊: Current diabetes reports
• 影响因子: 4.2
• 作者: Berg,DavidD;Kolkailah,AhmedA;Sarraju,Ashish;Kerchberger,AnneMarie;Eljalby,Mahmoud;McGuire,DarrenK
• 通讯作者: McGuire,DarrenK