Using MVRDL to increase the FDA Vet-LRN sample analysis capacity during animal food/feed emergency events

使用 MVRDL 提高动物食品/饲料紧急事件期间 FDA Vet-LRN 样品分析能力

• 批准号: 10569420
• 负责人: Lanny W. Pace
• 金额: $ 4.37万
• 依托单位: MISSISSIPPI STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-08-01 至 2027-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10569420
• 关键词: Using; MVRDL; increase; FDA; Vet

Project Summary The Mississippi Veterinary Research and Diagnostic Laboratory (MVRDL) is a full service, AAVLD accredited, all species, central reference laboratory. Our work force includes 10 faculty members (pathologists, poultry veterinarians, microbiologists, virologists, and molecular biologists) and approximately 28 staff positions. The Microbiology section personnel consists of a section supervisor (DVM, MS and PhD in Veterinary Sciences) with more than 30 years of clinical and research microbiology experience, a laboratory coordinator with 25 years of microbiology experience and two medical technologists with over 10 years of clinical laboratory experience each. The section analyzes samples from approximately 3000 accessions per year from which over 9000 procedures (aerobic cultures, anaerobic cultures, antimicrobial susceptibility tests) are completed. The Molecular Diagnostics section personnel consists of a section supervisor (MS and PhD in Animal Nutrition and Veterinary Medical Science) with more than 7 years of clinical and research molecular diagnostic experience, two laboratory technologists with more than 15 years of molecular diagnostic experience, and one laboratory technologist with 1year of molecular diagnostic experience. The section analyzes over 2500 accessions per year from which over 6000 procedures (PCR and gene sequencing) are completed. Through our participation in this collaborative agreement, we agree to participate in the three key project areas: (1) Participation in FDA/Vet-LIRN sample analysis (2) Providing analytical data for potential regulatory use (3) Participation in small-scale method development, method validation and matrix extension work as determined by the VPO. The MVRDL participates as a source lab for the Vet-LIRN antimicrobial resistance and whole genome sequencing projects. MVRDL has the capacity and is willing to offer its’ services to increase the capacity of the VPO in handling increased sample workflow during emergencies. MVRDL is committed to performing these services in an efficient, accurate and timely fashion and to reporting the results to the required agency.

项目摘要 密西西比兽医研究和诊断实验室（MVRDL）是一个全方位服务，AAVLD认证， 所有种属，中心参考实验室。我们的工作人员包括10名教职员工（病理学家，家禽 兽医、微生物学家、病毒学家和分子生物学家）以及大约28个工作人员职位。 微生物学部门人员包括部门主管（兽医学博士、硕士和博士 拥有30多年的临床和研究微生物学经验，实验室协调员 拥有25年的微生物学经验和两名拥有10年以上临床经验的医学技术人员， 每个实验室的经验该部分分析了来自每年约3000份材料的样品， 其中超过9000个程序（需氧培养，厌氧培养，抗菌药物敏感性试验） 完成 分子诊断部门人员包括部门主管（动物营养学硕士和博士 和兽医科学），具有超过7年的临床和研究分子诊断 两名具有15年以上分子诊断经验的实验室技术人员， 具有1年分子诊断经验实验室技术人员。该部分分析了2500多个 每年完成6000多个程序（PCR和基因测序）。 通过参与这一合作协议，我们同意参与三个关键项目领域： (1)参与FDA/Vet-LIRN样本分析 (2)提供分析数据用于潜在的监管用途 (3)参与小规模方法开发、方法验证和基质扩展工作， 由VPO决定。 MVRDL作为Vet-LIRN抗生素耐药性和全基因组的源实验室参与其中 排序项目。 MVRDL有能力并愿意提供服务，以增加VPO的处理能力 增加紧急情况下的样本工作流程。MVRDL致力于以一种 有效、准确和及时地进行，并向所需机构报告结果。