Using MVRDL to increase the FDA Vet-LRN sample analysis capacity during animal fo

使用 MVRDL 提高动物实验期间 FDA Vet-LRN 样品分析能力

• 批准号: 9126286
• 负责人: Michael John Mauel
• 金额: $ 1.65万
• 依托单位: MISSISSIPPI STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-09-01 至 2017-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9126286
• 关键词: Using; MVRDL; increase; FDA; Vet

Project Summary The Mississippi Veterinary Research and Diagnostic Laboratory (MVRDL) is a full service, AAVLD accredited, all species, central reference laboratory for the Mississippi Veterinary Diagnostic System. The MVRDL and PRDL conduct all of the regulatory testing done within our state laboratory system, including any testing done as part of the NAHLN. The normal work force for these two laboratories includes 10 faculty members (pathologists, poultry veterinarians, microbiologists, virologists, and molecular biologists) and approximately 30 staff positions. The laboratories are housed in one 40,000 square foot facility in Pearl, MS. The Microbiology section is housed in the main laboratory with 1651sqft devoted to the section. The section personnel consist of: a section supervisor with a PhD in Microbiology (more than 30 years in clinical and research microbiology) and two technicians with 3 years and 15 years microbiology experience. The section analyses approximately 5,200 samples per year submitted by a variety of sources including: veterinary clinics, in house necropsies, poultry facilities, wildlife agencies and zoos. The laboratory has been a member of the Veterinary Laboratory Response Network (Vet- LRN) since August 2011. Through our participation in this collaborative agreement we agree to participate in the three key project areas: (1) Participation in FDA/Vet-LRN sample analysis. a. Surveillance assignments as designated by the VPO. b. Animal food/drug emergency outbreak testing (in coordination with State analytical requirements). c. Large-scale animal food/drug emergency event surge capacity (in coordination with State analytical requirements). (2) Providing analytical data for potential regulatory use through: a. Use of standardized methods, equipment platforms, and reporting methods (standardized analytical worksheets and electronic results reporting). b. Participation in proficiency testing and method training provided by the VPO. c. Implementation of standardized quality management systems for laboratories as determined by the VPO (3) Participation in small-scale method development, method validation and matrix extension work as determined by the VPO. MVRDL has the capacity and is willing to offer its' services to increase the capacity of the VPO in handling increased sample workflow during emergencies. MVRDL is committed to performing these services in an efficient, accurate and timely fashion and to reporting the results to the required agency.

项目摘要 密西西比州兽医研究和诊断实验室(MVRDL)是一个完整的 服务，AAVLD认证，所有物种，密西西比河中心参考实验室 兽医诊断系统。MVRDL和PRDL进行所有的监管 在我们的州实验室系统内进行的测试，包括作为 NAHLN。这两个实验室的正常工作人员包括10名教职员工。 (病理学家、家禽兽医、微生物学家、病毒学家和分子 生物学家)和大约30个工作人员职位。这些实验室都设在一个 珍珠的设施面积为40,000平方英尺。 微生物学部分设在主实验室，1651平方英尺专门用于 一节。科员包括：科级主管一名，具有博士学位 微生物学(在临床和研究微生物学方面有30多年的经验)和 具有3年和15年微生物学工作经验的技术人员。横断面分析 每年约有5,200份样品由各种来源提交，包括： 兽医诊所、室内尸检、家禽设施、野生动物机构和动物园。这个 实验室一直是兽医实验室反应网络(Vet- LRN(LRN)自2011年8月以来。 通过参与这项合作协议，我们同意参与 三个关键项目领域： (1)参与FDA/Vet-LRN样品分析。 A.VPO指定的监视任务。 B.动物性食品/药物紧急暴发检测(与国家协调 分析要求)。 C.大型动物性食品/药品应急事件突增能力(协同 符合国家分析要求)。 (2)通过以下方式为潜在的监管用途提供分析数据： A.使用标准化方法、设备平台和报告方法 (标准化分析工作表和电子结果报告)。 B.参加VPO提供的能力测试和方法培训。 C.为实验室实施标准化的质量管理体系，如 由VPO确定 (3)参与小规模方法开发、方法验证和矩阵 VPO确定的扩展工作。 MVRDL有能力并愿意提供其服务，以增加 VPO在处理紧急情况时增加了样本工作流程。MVRDL为 致力于以高效、准确和及时的方式提供这些服务 向所需机构报告结果。