Hands-on Education and Research for Biomedical and Analytical Learning (HERBAL)

生物医学和分析学习的实践教育和研究（HERBAL）

• 批准号: 10665331
• 负责人: David C Rowley
• 金额: $ 26.77万
• 依托单位: UNIVERSITY OF RHODE ISLAND
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-03 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10665331
• 关键词: Biomedical Research; Biotechnology; CCL7 gene; Chromatography; Clinical; Collaborations; Complement; Computers; Core Facility; Creativeness; Curiosities; Custom; Data; Development; Drug Compounding; Education; Educational Curriculum; Educational process of instructing; Educational workshop; Enrollment; Environment; Equipment; Event; Faculty; Food; Funding; Future; Game Based Learning; Geography; Goals; Government; Growth; Health; Herbal Medicine; High Pressure Liquid Chromatography; High School Faculty; High School Student; Home; Human; Imagination; Industrialization; Informatics; Institution; Instruction; Laboratories; Learning; Learning Module; Libraries; Mass Spectrum Analysis; Medicinal Plants; Medicine; Mentors; Mentorship; Methods; Molecular Biology; Names; Online Systems; Participant; Personal Satisfaction; Pharmaceutical Chemistry; Pharmacy facility; Plant Extracts; Plants; Positioning Attribute; Problem Solving; Property; Research; Research Personnel; Resources; Rhode Island; Role; Sampling; Science; Science, Technology, Engineering and Mathematics; Services; Societies; Source; Specimen; Students; Teacher Professional Development; Techniques; Technology; Therapeutic; Traditional Medicine; Training; Translating; Underrepresented Populations; Universities; career; college; design; digital media; drug discovery; experience; faculty mentor; high school; high throughput screening; informatics tool; innovation; inquiry-based learning; instructor; instrumentation; interest; junior high school; laboratory curriculum; liquid chromatography mass spectrometry; literacy; mathematical learning; method development; neighborhood disadvantage; online classroom; peer coaching; programs; rural area; secondary metabolite; skills; student training; summer program; summer research; teacher; teaching laboratory; theories; undergraduate research experience; undergraduate student; urban area

PROJECT SUMMARY/ABSTRACT Life-long education and learning in science, technology, engineering, and math (STEM) is necessary for society at large to adapt to a 21st century world and beyond. This is especially true at the high school level, where students begin to translate the imagination, discovery, and curiosity of middle school science to higher-level science and analysis, which will then advance further when university studies begin. Enhancing STEM literacy requires that science, technology, engineering, and math training be accessible and engaging to high school studies, well before university studies even begin. Faculty in the College of Pharmacy at the University of Rhode Island train upper-division undergraduate students in course-based undergraduate research experiences or CUREs in medicinal chemistry. Course participants become more than just learners; they become motivated researchers involved in a genuine scientific effort designed to enable future biomedical discoveries. One deliverable that students create during their medicinal chemistry course is a plant extract library from specimens in the Heber W. Youngken Jr. Medicinal Garden. This library is named PRISM - the Principal Rhode Island Secondary Metabolite library. We propose to extend the concept of a medicinal chemistry CURE and authentic research experiences to the high school level (9-12 grades) by developing HERBAL: Hands-on Education and Research for Biomedical and Analytical Learning. HERBAL will pair research in the laboratory with game-based online classroom modules to teach theory and methods of medicinal plant and herbal product analysis during the academic year. Summer sessions will allow students in the HERBAL program to analyze samples they themselves have generated on cutting-edge instrumentation available in the University of Rhode Island’s teaching laboratories. Additionally, we will focus on the beneficial wellness aspects of herbals and their integrated role in our biomedicine along with artistic and creative opportunities connecting medicinal plant research to drawing and illustration. The HERBAL program will consist of 1) teacher training workshops to educate instructors on how to deliver the HERBAL academic year program. 2) Teacher training will be followed by an academic laboratory course for students with game-based learning modules to train students in theory and application. 3) Following completion of the academic year, students will attend a summer course in chromatography, mass spectrometry, and informatics analysis. This summer course will be complemented with mentorship, career enhancement activities, guest speakers on herbal medicine, and artistic and wellness events. HERBAL’s focus on curricular and method development activities augmented with interactive digital-media based learning modules will shift the paradigm in how these students traditionally learn science, which will increase student interest in STEM topics and enhance their STEM identity.

项目总结/摘要 科学、技术、工程和数学（STEM）的终身教育和学习对社会是必要的 以适应21世纪及以后的世界。在高中阶段尤其如此， 学生开始将想象力、发现和对中学科学的好奇心转化为更高层次的知识 科学和分析，这将进一步推进时，大学学习开始。提高STEM素养 要求高中学生能够接受科学、技术、工程和数学培训并参与其中 甚至在大学学习开始之前就开始了。罗德岛大学药学院教师 岛屿训练高年级本科生在课程为基础的本科研究经验，或 药物化学治疗。课程参与者不仅仅是学习者;他们变得有动力 研究人员参与了真正的科学努力，旨在使未来的生物医学发现。一 学生在药物化学课程中创建的可交付成果是从标本中提取的植物提取物库 在Heber W.小永健药园。这个图书馆被命名为PRISM --罗得岛的校长 二级代谢物文库。我们建议扩展药物化学的概念治愈和真实的 研究经验，以高中水平（9-12年级）通过开发草药：动手教育和 生物医学和分析学习研究。HERBAL将实验室研究与基于游戏的 在线课堂模块，教授药用植物和草药产品分析的理论和方法， 学年。夏季课程将允许学生在草药计划分析样品， 他们自己已经在罗得岛大学的尖端仪器上产生了 教学实验室此外，我们将专注于草药的有益健康方面及其综合 沿着艺术和创造性的机会，将药用植物研究与 绘图和插图。草药计划将包括1）教师培训讲习班， 教师如何提供草药学年计划。2)教师培训后， 学术实验室课程的学生与游戏为基础的学习模块，以培养学生的理论和 应用程序. 3)学年结束后，学生将参加一个夏季课程， 色谱法、质谱法和信息学分析。这个夏季课程将与 导师制、职业提升活动、草药特邀演讲者以及艺术和健康活动。 HERBAL专注于通过互动数字媒体增强的课程和方法开发活动 基于学习模块将改变这些学生传统上学习科学的模式， 提高学生对STEM主题的兴趣，增强他们的STEM身份。