Sexually Transmited Infection Testing Risk and Prevention among Trans Women (STRiP-T)

跨性别女性性传播感染检测风险和预防 (STRiP-T)

• 批准号: 10547849
• 负责人: Makella S. Coudray
• 金额: $ 12.66万
• 依托单位: UNIVERSITY OF CENTRAL FLORIDA
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-24 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10547849
• 关键词: Address; Affect; Appointment; Area; Biological; Birth; Caring; Characteristics; Chlamydia trachomatis; Collaborations; Data; Development; Discrimination; Early Diagnosis; Early treatment; Epidemiologic Methods; Epidemiology; Face; Florida; Genital; Genitalia; Geographic Information Systems; Goals; Grant; HIV; Health Disparities Research; Health Services Accessibility; Healthcare; Individual; Infection prevention; Intervention; Interview; Knowledge; Laboratories; Literature; Mentors; Mentorship; Methodology; Methods; National Institute on Minority Health and Health Disparities; Neighborhoods; Neisseria gonorrhoeae; Pathway Analysis; Patient Self-Report; Patients; Phase; Pilot Projects; Population; Positioning Attribute; Predisposition; Prevalence; Prevention; Prevention Research; Procedures; Provider; Qualitative Research; Reporting; Research; Research Methodology; Research Personnel; Research Training; Risk; Risk Factors; STI prevention; Sampling; Scientist; Secure; Sexual and Gender Minorities; Sexually Transmitted Diseases; Site; Social Network; Social support; Specimen; Surveys; Syphilis; Target Populations; Testing; Time; Tissues; Training; Universities; Woman; acceptability and feasibility; barrier to care; base; career; career development; community based research; community-level factor; cultural competence; efficacy evaluation; experience; gender minority health disparity; genital surgery; health care availability; health care settings; health disparity; health inequalities; infection risk; innovation; intervention mapping; male; marginalized population; minority health disparity; novel strategies; preventive intervention; recruit; rectal; screening; sexual risk behavior; skills; social; social capital; social epidemiology; social stigma; spatial epidemiology; tenure track; transgender; transgender women

PROJECT SUMMARY/ABSTRACT Career Goal: My long-term career goals are to a) secure a full-time tenure track academic appointment; and b) become an independent investigator in human immunodeficiency virus/sexually transmitted infection (HIV/STI) risk and prevention research among transgender women (trans women, women assigned male at birth). This research and training grant will provide me with the opportunity to enhance my research skills as a Postdoctoral Scholar at the University of Central Florida and to successfully transition to an STI intervention scientist that addresses prominent health inequalities faced by trans women. Career Development: This K99/R00 research and training plan will catalyze my efforts to acquire the advanced training necessary to assess the feasibility, acceptability, and validity of self-collected samples versus clinician collected samples for STI testing and examine the relationship between combined socio-spatial network characteristics (e.g., social capital, access to care) and STI risk among trans women. During the K99 phase my training goals consist of a) mixed methods research, by gaining skills in qualitative research and analysis; b) intervention mapping and c) social and spatial epidemiology methods, by gaining skills in social network analysis and geographic information systems. Research Objective: This K99/R00 application proposes to integrate my prior experience in robust quantitative methods with new knowledge in mixed methods research, intervention mapping and social and spatial epidemiology methods in order to enhance my independence as a researcher focused on addressing STI health disparities within a health care setting, which the National Institute on Minority Health and Health Disparities (NIMHD) has identified as a major priority. Specific Aims: Aim 1: Conduct pilot study to explore the acceptability, feasibility, and validity of self-collected vs. clinician collected genital and non-genital samples among trans women with and without neovaginas to detect STIs using mixed methodology (quantitative surveys and in-depth interviews). Aim 2: Examine multi-site (genital, rectal, pharyngeal) STI prevalence among trans women with and without neovaginas. Aim 3: Characterize the relationship between social and spatial network characteristics (e.g., network size, social support, neighborhood characteristics) and STI risk among trans women with and without neovaginas. Mentorship team: My efforts will be guided by an accomplished, interdisciplinary team of mentors (with prior experience working together) committed to support my transition to an independent investigator.

项目概要/摘要 职业目标：我的长期职业目标是：a）获得全职终身教职学术任命；和 b) 成为人类免疫缺陷病毒/性传播感染（HIV/STI）的独立研究者 跨性别女性（跨性别女性、出生时被指定为男性的女性）的风险和预防研究。这 研究和培训补助金将为我提供提高博士后研究技能的机会 中佛罗里达大学学者并成功转型为性传播感染干预科学家 解决跨性别女性面临的突出健康不平等问题。职业发展：K99/R00 研究 培训计划将促进我努力获得评估可行性所需的高级培训， 自我采集样本与临床医生采集样本进行性传播感染检测的可接受性和有效性 检查综合社会空间网络特征之间的关系（例如，社会资本、获得资源的机会） 护理）和跨性别女性的性传播感染风险。在 K99 阶段，我的训练目标包括 a) 混合方法 研究，通过获得定性研究和分析的技能； b) 干预绘图 c) 社会和空间 流行病学方法，通过获得社交网络分析和地理信息系统的技能。 研究目标：这个 K99/R00 应用程序建议整合我之前在稳健定量方面的经验 混合方法研究、干预制图以及社会和空间方面的新知识方法 流行病学方法，以增强我作为专注于解决性传播感染健康问题的研究人员的独立性 国家少数民族健康和健康差异研究所 （NIMHD）已将其确定为主要优先事项。具体目标： 目标 1：进行试点研究以探索可接受性， 跨性别者自行采集与临床医生采集的生殖器和非生殖器样本的可行性和有效性 有或没有新阴道的女性使用混合方法（定量调查和深入研究）检测性传播感染 采访）。目标 2：检查跨性别女性中多部位（生殖器、直肠、咽部）性传播感染的患病率 没有新阴道。目标 3：描述社会和空间网络特征之间的关系（例如， 网络规模、社会支持、邻里特征）和跨性别女性的性传播感染风险 新阴道。导师团队：我的努力将由一支经验丰富的跨学科导师团队指导 （具有之前的合作经验）致力于支持我向独立调查员的过渡。