At the Intersection of HIV and COVID-19: Medicaid Data as a Complement to Cohort Studies
HIV 和 COVID-19 的交叉点:医疗补助数据作为队列研究的补充
基本信息
- 批准号:10548472
- 负责人:
- 金额:$ 81.87万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2022
- 资助国家:美国
- 起止时间:2022-06-10 至 2027-05-31
- 项目状态:未结题
- 来源:
- 关键词:AIDS preventionAIDS/HIV problemAcquired Immunodeficiency SyndromeAcuteAcute DiseaseAdverse effectsAgeAlcoholsAnti-Retroviral AgentsAreaCD4 Lymphocyte CountCOVID-19COVID-19 impactCOVID-19 pandemicCOVID-19 pandemic effectsCOVID-19 riskCOVID-19 screeningCOVID-19 severityCaringCessation of lifeCitiesClinicalCohort StudiesCommunitiesComplementContinuity of Patient CareCountyDataDiabetes MellitusDiagnosisDiseaseEnrollmentEpidemicEthnic OriginFutureGeographic LocationsGeographyGoalsGovernmentHIVHIV diagnosisHealthHealth Services AccessibilityHealthcareHepatitis C TherapyHospitalizationHuman immunodeficiency virus testHyperlipidemiaHypertensionIncidenceInflammatoryInfrastructureInpatientsInterventionLocal GovernmentMedicaidMedicalMental HealthOperative Surgical ProceduresOutcomeOverdosePersonsPharmaceutical PreparationsPneumoniaPoliciesPopulationPreventionPreventive carePreventive screeningProbabilityPublic HealthRaceReportingRiskRisk FactorsSARS-CoV-2 infectionScreening for cancerServicesSymptomsSyndromeTelemedicineTestingTimeUnited StatesViralViral Load resultVisitWashingtonWorkacute careadverse outcomebasebehavioral healthbeneficiarycombatcomorbiditycomparison groupcoronavirus diseasegeographic differencehealth care service utilizationhigh riskimprovedinterestpandemic diseasepre-exposure prophylaxisregional differenceremote health carerural settingscreeningsevere COVID-19sexsocial health determinantsuptake
项目摘要
ABSTRACT
The Coronavirus Disease 2019 (COVID-19) pandemic has had an unprecedented impact on the lives of people
worldwide. Yet, the effect on persons living with HIV (PLWH) is not known. Emerging evidence suggests that
PLWH have a similar or modestly higher risk of COVID-19 acquisition, and higher risk for worse COVID-19
outcomes, including hospitalization and death. However, the data has been mixed as several studies have
suggested no difference in clinical outcomes. Several studies also found that outcomes are worse among
those without viral suppression and those with lower CD4 counts, highlighting the importance of continued HIV
care. Yet, early reports suggest that COVID-19 has disrupted services across the HIV care continuum. As the
pandemic continues to unfold, it is critical to better characterize the relationship between COVID and outcomes
among PLWH. In addition, we need to identify how the pandemic and the public health strategies to combat
the pandemic impacted the provision of care for PLWH, as well as whether any adverse effects are lasting.
Approximately 40% of PLWH are enrolled in Medicaid. The proposed project will include Medicaid beneficiaries
from 27 states and Washington, DC between 2018 and 2024 with a conservative estimate of 25 million
beneficiaries and 275,000 PLWH enrolled annually. Medicaid is an important complement to HIV cohort
studies as it affords us the breadth of data to evaluate differences by geographic location, social determinants
of health at the community level, as well as among important sub-populations. We will assess the relationship
between HIV and COVID-19 disease, including on hospitalization due to COVID-19 and adverse conditions
due to COVID like post-acute sequala of COVID-19 (PASC). We will also evaluate the impact of the COVID19
pandemic on the provision of care for prevention of HIV and HIV care. We will assess care across the HIV care
continuum including PrEP prescription, HIV testing, and annual HIV care visits, viral load tests, and ARV
medication possession ratio. We will also evaluate impacts on the provision of care for non-HIV conditions,
including annual wellness visits, preventive screenings and health condition management. We will compare
care rates during the pre-COVID period (2001-2019), acute COVID period (2020-2021), and post-acute COVID
period (2022-2024) overall and by geographic location (state, urban/rural, local government area [LGA],
smallest government region e.g. county, city, town, etc.) and regional severity of COVID-19 cases and COVID-
19 policies. Findings from the proposed study will help inform and target interventions to improve care for
PLWH in the future.
抽象的
2019 年冠状病毒病(COVID-19)大流行对人们的生活产生了前所未有的影响
全世界。然而,对艾滋病毒感染者(PLWH)的影响尚不清楚。新出现的证据表明
PLWH 感染 COVID-19 的风险相似或稍高,并且感染 COVID-19 的风险更高
结果,包括住院和死亡。然而,数据好坏参半,因为多项研究表明
表明临床结果没有差异。几项研究还发现,结果更差
那些没有病毒抑制的人和那些 CD4 计数较低的人,强调了持续艾滋病毒的重要性
关心。然而,早期报告表明,COVID-19 已经扰乱了整个艾滋病毒护理连续体的服务。作为
大流行继续蔓延,更好地描述新冠病毒与结果之间的关系至关重要
感染者之中。此外,我们需要确定如何应对这一流行病和公共卫生战略
大流行影响了为感染者提供的护理,以及是否有任何不利影响是持久的。
大约 40% 的 PLWH 参加了医疗补助计划。拟议项目将包括医疗补助受益人
2018 年至 2024 年间,来自 27 个州和华盛顿特区,保守估计为 2500 万
每年有 275,000 名感染者和受益者参加。医疗补助是艾滋病毒队列的重要补充
研究,因为它为我们提供了广泛的数据来评估地理位置、社会决定因素的差异
社区一级以及重要亚人群的健康状况。我们将评估双方关系
HIV 和 COVID-19 疾病之间的关系,包括因 COVID-19 和不利条件而住院的情况
由于像 COVID-19 (PASC) 急性后遗症这样的新冠病毒。我们还将评估新冠肺炎疫情的影响
为预防艾滋病毒和艾滋病毒护理提供护理。我们将评估整个艾滋病毒护理的护理
连续体,包括 PrEP 处方、HIV 检测、年度 HIV 护理就诊、病毒载量检测和 ARV
药品拥有率。我们还将评估对非艾滋病毒状况护理的影响,
包括年度健康检查、预防性筛查和健康状况管理。我们会比较
新冠肺炎前期(2001-2019 年)、新冠急性期(2020-2021 年)和新冠急性期后的护理率
期间(2022-2024)总体和按地理位置(州、城市/农村、地方政府区域 [LGA]、
最小的政府区域,例如县、市、镇等)以及 COVID-19 病例和 COVID-19 病例的区域严重程度
19项政策。拟议研究的结果将有助于提供信息并确定干预措施的目标,以改善对患者的护理
未来的感染者。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Corinne E. Joshu其他文献
Determinants of receipt of prostate cancer screening among men living with HIV enrolled in an urban HIV Clinic in the United States over the period of 2000–2020
在2000 - 2020年期间,在美国艾滋病毒诊所招收的艾滋病毒的男性接受前列腺癌筛查的决定因素
- DOI:
10.1016/j.ypmed.2024.108000 - 发表时间:
2024-07-01 - 期刊:
- 影响因子:3.200
- 作者:
Filip Pirsl;Jeanne C. Keruly;Richard D. Moore;Bryan Lau;Corinne E. Joshu - 通讯作者:
Corinne E. Joshu
Guidelines:Colorectal cancer/Colonoscopy surveillance/The elderly and stopping rules
指南:结直肠癌/结肠镜监测/老年人和停止规则
- DOI:
- 发表时间:
2019 - 期刊:
- 影响因子:0
- 作者:
Jacqueline E. Rudolph;Keri L. Calkins;Xueer Zhang;Yiyi Zhou;Xiaoqiang Xu;Eryka L Wentz;Corinne E. Joshu;Bryan Lau - 通讯作者:
Bryan Lau
Incidence of prostate cancer in Medicaid beneficiaries with and without HIV in 2001–2015 in 14 states
2001 年至 2015 年 14 个州的医疗补助受益人中感染和未感染 HIV 的前列腺癌发病率
- DOI:
10.1101/2024.05.24.24307676 - 发表时间:
2024 - 期刊:
- 影响因子:0
- 作者:
Filip Pirsl;Keri L. Calkins;Jacqueline E. Rudolph;Eryka L Wentz;Xiaoqiang Xu;Bryan Lau;Corinne E. Joshu - 通讯作者:
Corinne E. Joshu
Receipt of prostate-specific antigen test in Medicaid beneficiaries with and without HIV in 2001-2015 in 14 states.
2001 年至 2015 年,14 个州的感染和未感染 HIV 的医疗补助受益人接受了前列腺特异性抗原检测。
- DOI:
10.1089/aid.2023.0142 - 发表时间:
2024 - 期刊:
- 影响因子:1.5
- 作者:
Filip Pirsl;Keri L. Calkins;Jacqueline E. Rudolph;Eryka L Wentz;Xiaoqiang Xu;Yiyi Zhou;Bryan Lau;Corinne E. Joshu - 通讯作者:
Corinne E. Joshu
Subsequent risk of cancer among adults with peripheral artery disease in the community: The atherosclerosis risk in communities (ARIC) study
社区中患有外周动脉疾病的成年人患癌症的后续风险:社区动脉粥样硬化风险(ARIC)研究
- DOI:
10.1016/j.ijcard.2024.132577 - 发表时间:
2025-01-01 - 期刊:
- 影响因子:3.200
- 作者:
Shoichiro Nohara;Yejin Mok;Jeremy R. Van't Hof;Maya Salameh;Corinne E. Joshu;Elizabeth A. Platz;Roberta Florido;Kunihiro Matsushita - 通讯作者:
Kunihiro Matsushita
Corinne E. Joshu的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Corinne E. Joshu', 18)}}的其他基金
At the Intersection of HIV and COVID-19: Medicaid Data as a Complement to Cohort Studies
HIV 和 COVID-19 的交叉点:医疗补助数据作为队列研究的补充
- 批准号:
10642852 - 财政年份:2022
- 资助金额:
$ 81.87万 - 项目类别:
Medicaid data as a complement to cohort studies for investigating cancers among older people with HIV
医疗补助数据作为队列研究的补充,用于调查老年艾滋病毒感染者的癌症
- 批准号:
10132275 - 财政年份:2020
- 资助金额:
$ 81.87万 - 项目类别:
Medicaid data as a complement to cohort studies for investigating cancers among older people with HIV
医疗补助数据作为队列研究的补充,用于调查老年艾滋病毒感染者的癌症
- 批准号:
10580704 - 财政年份:2020
- 资助金额:
$ 81.87万 - 项目类别:
Medicaid data as a complement to cohort studies for investigating cancers among older people with HIV
医疗补助数据作为队列研究的补充,用于调查老年艾滋病毒感染者的癌症
- 批准号:
10364673 - 财政年份:2020
- 资助金额:
$ 81.87万 - 项目类别:
Medicaid data as a complement to cohort studies for investigating cancers among older people with HIV
医疗补助数据作为队列研究的补充,用于调查老年艾滋病毒感染者的癌症
- 批准号:
10013582 - 财政年份:2020
- 资助金额:
$ 81.87万 - 项目类别:














{{item.name}}会员




