At the Intersection of HIV and COVID-19: Medicaid Data as a Complement to Cohort Studies

HIV 和 COVID-19 的交叉点:医疗补助数据作为队列研究的补充

基本信息

  • 批准号:
    10548472
  • 负责人:
  • 金额:
    $ 81.87万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2022
  • 资助国家:
    美国
  • 起止时间:
    2022-06-10 至 2027-05-31
  • 项目状态:
    未结题

项目摘要

ABSTRACT The Coronavirus Disease 2019 (COVID-19) pandemic has had an unprecedented impact on the lives of people worldwide. Yet, the effect on persons living with HIV (PLWH) is not known. Emerging evidence suggests that PLWH have a similar or modestly higher risk of COVID-19 acquisition, and higher risk for worse COVID-19 outcomes, including hospitalization and death. However, the data has been mixed as several studies have suggested no difference in clinical outcomes. Several studies also found that outcomes are worse among those without viral suppression and those with lower CD4 counts, highlighting the importance of continued HIV care. Yet, early reports suggest that COVID-19 has disrupted services across the HIV care continuum. As the pandemic continues to unfold, it is critical to better characterize the relationship between COVID and outcomes among PLWH. In addition, we need to identify how the pandemic and the public health strategies to combat the pandemic impacted the provision of care for PLWH, as well as whether any adverse effects are lasting. Approximately 40% of PLWH are enrolled in Medicaid. The proposed project will include Medicaid beneficiaries from 27 states and Washington, DC between 2018 and 2024 with a conservative estimate of 25 million beneficiaries and 275,000 PLWH enrolled annually. Medicaid is an important complement to HIV cohort studies as it affords us the breadth of data to evaluate differences by geographic location, social determinants of health at the community level, as well as among important sub-populations. We will assess the relationship between HIV and COVID-19 disease, including on hospitalization due to COVID-19 and adverse conditions due to COVID like post-acute sequala of COVID-19 (PASC). We will also evaluate the impact of the COVID19 pandemic on the provision of care for prevention of HIV and HIV care. We will assess care across the HIV care continuum including PrEP prescription, HIV testing, and annual HIV care visits, viral load tests, and ARV medication possession ratio. We will also evaluate impacts on the provision of care for non-HIV conditions, including annual wellness visits, preventive screenings and health condition management. We will compare care rates during the pre-COVID period (2001-2019), acute COVID period (2020-2021), and post-acute COVID period (2022-2024) overall and by geographic location (state, urban/rural, local government area [LGA], smallest government region e.g. county, city, town, etc.) and regional severity of COVID-19 cases and COVID- 19 policies. Findings from the proposed study will help inform and target interventions to improve care for PLWH in the future.
摘要 冠状病毒病2019年(新冠肺炎)大流行对人们的生活产生了前所未有的影响 全世界。然而,对艾滋病毒携带者(PLWH)的影响尚不清楚。新出现的证据表明 普华永道有类似或略高的新冠肺炎收购风险,新冠肺炎恶化的风险更高 结果,包括住院和死亡。然而,就像几项研究一样,数据一直是喜忧参半的 表明在临床结果上没有差别。几项研究还发现,结果更差的是 那些没有病毒抑制的人和那些CD4计数较低的人,突出了继续感染艾滋病毒的重要性 关心。然而,早期报告表明,新冠肺炎已经扰乱了整个艾滋病毒护理连续体系的服务。作为 大流行仍在继续,更好地描述COVID与结果之间的关系至关重要 在PLWH中。此外,我们需要确定大流行和公共卫生战略如何抗击 这场大流行影响了对长春市妇幼保健院的护理,以及是否会产生任何持久的不利影响。 大约40%的PLWH参加了医疗补助。拟议的项目将包括医疗补助受益人 来自27个州和华盛顿特区,2018年至2024年,保守估计为2500万 受益者和每年登记的275,000名妇女之家。医疗补助是对艾滋病毒队列的重要补充 研究是因为它为我们提供了广泛的数据,以评估地理位置、社会决定因素的差异 在社区一级以及在重要的亚人群中,提高卫生保健水平。我们将评估两国关系 艾滋病毒与新冠肺炎病之间的关系,包括因新冠肺炎和不良条件而住院 由于新冠肺炎(PASC)的类似冠状病毒的急性后遗症。我们还将评估COVID19的影响 关于提供预防艾滋病毒的护理和艾滋病毒护理的大流行。我们将评估整个HIV护理的护理 包括PrEP处方、HIV检测和每年的HIV护理访问、病毒负载测试和ARV 药物持有率。我们还将评估对提供非艾滋病毒疾病护理的影响, 包括年度健康检查、预防性筛查和健康状况管理。我们会比较一下 COVID前时期(2001-2019年)、急性COVID期(2020-2021年)和急性COVID后时期的护理率 期间(2022-2024)总体和按地理位置(州、城市/农村、地方政府地区[LGA]、 最小的政府区域,例如县、市、镇等)以及新冠肺炎病例和冠状病毒感染的地区严重性- 19条政策。这项拟议研究的结果将有助于提供信息并有针对性地进行干预,以改善对 未来的PLWH。

项目成果

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Corinne E. Joshu其他文献

Determinants of receipt of prostate cancer screening among men living with HIV enrolled in an urban HIV Clinic in the United States over the period of 2000–2020
在2000 - 2020年期间,在美国艾滋病毒诊所招收的艾滋病毒的男性接受前列腺癌筛查的决定因素
  • DOI:
    10.1016/j.ypmed.2024.108000
  • 发表时间:
    2024-07-01
  • 期刊:
  • 影响因子:
    3.200
  • 作者:
    Filip Pirsl;Jeanne C. Keruly;Richard D. Moore;Bryan Lau;Corinne E. Joshu
  • 通讯作者:
    Corinne E. Joshu
Guidelines:Colorectal cancer/Colonoscopy surveillance/The elderly and stopping rules
指南:结直肠癌/结肠镜监测/老年人和停止规则
  • DOI:
  • 发表时间:
    2019
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Jacqueline E. Rudolph;Keri L. Calkins;Xueer Zhang;Yiyi Zhou;Xiaoqiang Xu;Eryka L Wentz;Corinne E. Joshu;Bryan Lau
  • 通讯作者:
    Bryan Lau
Incidence of prostate cancer in Medicaid beneficiaries with and without HIV in 2001–2015 in 14 states
2001 年至 2015 年 14 个州的医疗补助受益人中感染和未感染 HIV 的前列腺癌发病率
  • DOI:
    10.1101/2024.05.24.24307676
  • 发表时间:
    2024
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Filip Pirsl;Keri L. Calkins;Jacqueline E. Rudolph;Eryka L Wentz;Xiaoqiang Xu;Bryan Lau;Corinne E. Joshu
  • 通讯作者:
    Corinne E. Joshu
Receipt of prostate-specific antigen test in Medicaid beneficiaries with and without HIV in 2001-2015 in 14 states.
2001 年至 2015 年,14 个州的感染和未感染 HIV 的医疗补助受益人接受了前列腺特异性抗原检测。
  • DOI:
    10.1089/aid.2023.0142
  • 发表时间:
    2024
  • 期刊:
  • 影响因子:
    1.5
  • 作者:
    Filip Pirsl;Keri L. Calkins;Jacqueline E. Rudolph;Eryka L Wentz;Xiaoqiang Xu;Yiyi Zhou;Bryan Lau;Corinne E. Joshu
  • 通讯作者:
    Corinne E. Joshu
Subsequent risk of cancer among adults with peripheral artery disease in the community: The atherosclerosis risk in communities (ARIC) study
社区中患有外周动脉疾病的成年人患癌症的后续风险:社区动脉粥样硬化风险(ARIC)研究
  • DOI:
    10.1016/j.ijcard.2024.132577
  • 发表时间:
    2025-01-01
  • 期刊:
  • 影响因子:
    3.200
  • 作者:
    Shoichiro Nohara;Yejin Mok;Jeremy R. Van't Hof;Maya Salameh;Corinne E. Joshu;Elizabeth A. Platz;Roberta Florido;Kunihiro Matsushita
  • 通讯作者:
    Kunihiro Matsushita

Corinne E. Joshu的其他文献

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{{ truncateString('Corinne E. Joshu', 18)}}的其他基金

At the Intersection of HIV and COVID-19: Medicaid Data as a Complement to Cohort Studies
HIV 和 COVID-19 的交叉点:医疗补助数据作为队列研究的补充
  • 批准号:
    10642852
  • 财政年份:
    2022
  • 资助金额:
    $ 81.87万
  • 项目类别:
Medicaid data as a complement to cohort studies for investigating cancers among older people with HIV
医疗补助数据作为队列研究的补充,用于调查老年艾滋病毒感染者的癌症
  • 批准号:
    10132275
  • 财政年份:
    2020
  • 资助金额:
    $ 81.87万
  • 项目类别:
Medicaid data as a complement to cohort studies for investigating cancers among older people with HIV
医疗补助数据作为队列研究的补充,用于调查老年艾滋病毒感染者的癌症
  • 批准号:
    10580704
  • 财政年份:
    2020
  • 资助金额:
    $ 81.87万
  • 项目类别:
Medicaid data as a complement to cohort studies for investigating cancers among older people with HIV
医疗补助数据作为队列研究的补充,用于调查老年艾滋病毒感染者的癌症
  • 批准号:
    10364673
  • 财政年份:
    2020
  • 资助金额:
    $ 81.87万
  • 项目类别:
Medicaid data as a complement to cohort studies for investigating cancers among older people with HIV
医疗补助数据作为队列研究的补充,用于调查老年艾滋病毒感染者的癌症
  • 批准号:
    10013582
  • 财政年份:
    2020
  • 资助金额:
    $ 81.87万
  • 项目类别:
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