Molecular Biophysics Training Program

分子生物物理学培训计划

• 批准号: 10631072
• 负责人: Olga Boudker
• 金额: $ 21.22万
• 依托单位: WEILL MEDICAL COLL OF CORNELL UNIV
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-01 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10631072
• 关键词: Biophysics; Molecular; Training Programs

Abstract The Molecular Biophysics Training Program (MBTP) at the Weill Cornell Graduate School (WCGS) is built on a decades-long history of biophysics research and training at the two institutions comprising WCGS - Weill Cornell Medicine (WCM) and the Memorial Sloan-Kettering Cancer Center (MSKCC) located across the street from each other. MBTP will bring together biophysics trainees from two WCGS graduate bi-institutional programs: the Biochemistry & Structural Biology (BSB) program, part of the umbrella Biochemistry, Cell and Molecular Biology (BCMB) program and the Physiology, Biophysics and Systems Biology (PBSB) program. Union of the biophysics trainees in these two programs is a natural fit given that biophysics is inherently multidisciplinary – bringing together biology, chemistry, physics, computational biology, and mathematics. MBTP will provide: 1) outstanding learning and mentoring for predoctoral trainees in molecular biophysics; 2) world-class research opportunities; 3) a diverse and interactive community of students and faculty to foster scientific exchange and collaboration; 4) strong foundation in performing rigorous and reproducible scientific research and 5) knowledge of and exposure to various career paths for successful transition into the biomedical research workforce. The formation of the MBTP program is the latest in a nearly three-decade maturation of synergistic connections between WCM and MSKCC.

摘要 分子生物物理学培训计划（MBTP）在威尔康奈尔研究生院（WCGS）是建立在一个 组成WCGS的两个机构数十年的生物物理学研究和培训历史-威尔 康奈尔医学院（WCM）和纪念斯隆-凯特琳癌症中心（MSKCC）位于街对面 彼此隔离。MBTP将汇集来自两个WCGS研究生双机构的生物物理学学员 程序：生物化学与结构生物学（BSB）程序，伞生物化学，细胞和 分子生物学（BCMB）计划和生理学，生物物理学和系统生物学（PBSB）计划。 这两个项目的生物物理学实习生的联盟是一个自然的契合，因为生物物理学本质上是 多学科-汇集了生物学，化学，物理学，计算生物学和数学。 MBTP将提供：1）在分子生物物理学博士前实习生优秀的学习和指导; 2） 世界一流的研究机会; 3）学生和教师的多元化和互动社区，以促进 科学交流与合作; 4）在执行严谨和可重复的科学研究方面有坚实的基础 研究和5）知识和接触各种职业道路，以成功过渡到 生物医学研究人员。MBTP计划的形成是近三十年来最新的 WCM和MSKCC之间协同连接的成熟。

项目成果

Molecular basis for Nse5-6 mediated regulation of Smc5/6 functions.

Nse5-6 介导的 Smc5/6 功能调节的分子基础。

• DOI: 10.1073/pnas.2310924120
• 发表时间: 2023
• 期刊: Proceedings of the National Academy of Sciences of the United States of America
• 影响因子: 11.1
• 作者: Li,Shibai;Yu,You;Zheng,Jian;Miller-Browne,Victoria;Ser,Zheng;Kuang,Huihui;Patel,DinshawJ;Zhao,Xiaolan
• 通讯作者: Zhao,Xiaolan