Radiology Core

放射学核心

• 批准号: 10629120
• 负责人: JOSHUA S SHIMONY
• 金额: $ 28.45万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-01 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10629120
• 关键词: Adherence; Anatomy; Archives; Board Certification; Brain; Calibration; Clinical; Code; Cohort Studies; Complex; Computer software; Data; Data Set; Databases; Development; Diameter; Diffusion; Documentation; Elements; Ensure; Functional Magnetic Resonance Imaging; Funding; Future; Genetic; Goals; Grant; Horns; Human; Human Resources; Image; Individual; Interdisciplinary Study; Length; MRI Scans; Magnetic Resonance Imaging; Measurement; Measures; Methods; Mission; Neurological outcome; Outcome Measure; Output; Participant; Pathway Analysis; Patient Outcomes Assessments; Pediatric Hospitals; Performance; Phenotype; Population; Positioning Attribute; Procedures; Process; Protocol Compliance; Protocols documentation; Quality Control; Radiology Specialty; Reproducibility; Research; Research Personnel; Rest; Scanning; Schedule; Secure; Services; Side; Site; Spinal Cord; Standardization; Stream; Structure; Syringomyelia; Testing; Tonsil; Universities; Vertebral column; Washington; Work; career development; clinical center; clinical imaging; computerized data processing; data access; data acquisition; data archive; early-career faculty; follow-up; image archival system; imaging science; innovation; malformation; member; neural network; neuroimaging; radiological imaging; repository; research study; spectrograph; translational scientist

PROJECT SUMMARY Neuroimaging is a fundamental method for investigating the development of the human brain and spine structure and function in typically and atypically developing populations. MR imaging is key to support the aims of Park- Reeves Chiari & Syringomyelia Center (PRCSC) and the four sub-projects within the proposal. The goals of the Radiology imaging core (RC) are to provide comprehensive MRI service to the different projects within the PRCSC to facilitate imaging data acquisition. The RC will coordinate the initial and follow up MRI scans across all projects and cores. This will include close coordination with the administrative and clinical cores, clinical teams, and the Center for Clinical Imaging Research (CCIR) to guarantee scheduling at the appropriate times. The RC will perform the required steps to ensure quality control of the MRI scanners using regular phantom test scans and scan protocol compliance checks. Further, the RC will cover the full extent of handling of the MR imaging data, including using state-of-the art archiving software for all the PRCSC neuroimaging services. On the input side this includes uploading, anonymizing, and securely storing the data using the Park-Reeves CSC Centralized Neuroimaging Data Archive (CNDA). On the output side this includes giving access of the data to the project investigators to maximize the quality and impact of the PRCSC research by center investigators and their collaborators, securely distributing the raw and processed data to the different sub-projects as needed. The RC will assist with the procedures for standardized processing of the data for future use by the different sub- projects of the proposal. This includes simple anatomical measures, but also sophisticated software pipelines for processing of fMRI and DBSI data. Finally, the RC will promote new methods for analyzing MRI data and will provide a range of consultative and analytic services that will help PRCSC investigators, including new and early- stage investigators, incorporate imaging into their research efforts.

项目概要 神经影像学是研究人类大脑和脊柱结构发育的基本方法 并在典型和非典型发展人群中发挥作用。 MR 成像是支持 Park 目标的关键 Reeves Chiari 和脊髓空洞症中心 (PRCSC) 以及提案中的四个子项目。的目标 放射成像核心（RC）为不同项目提供全面的MRI服务 PRCSC 促进成像数据采集。 RC 将协调初始和后续 MRI 扫描 所有项目和核心。这将包括与行政和临床核心、临床 团队和临床影像研究中心 (CCIR)，以保证在适当的时间安排。 RC 将执行所需的步骤，以确保使用常规体模测试对 MRI 扫描仪进行质量控制 扫描和扫描协议合规性检查。此外，RC 将涵盖 MR 处理的全部范围 影像数据，包括对所有 PRCSC 神经影像服务使用最先进的存档软件。在 输入端，包括使用 Park-Reeves CSC 上传、匿名和安全存储数据 集中神经影像数据存档 (CNDA)。在输出方面，这包括授予数据访问权限 项目研究人员最大限度地提高中心研究人员的 PRCSC 研究质量和影响力 他们的合作者，根据需要将原始数据和处理后的数据安全地分发到不同的子项目。这 RC 将协助制定数据标准化处理程序，以供不同子部门未来使用 提案的项目。这包括简单的解剖测量，也包括复杂的软件管道 用于处理 fMRI 和 DBSI 数据。最后，RC 将推广分析 MRI 数据的新方法，并将 提供一系列咨询和分析服务，帮助 PRCSC 调查人员，包括新的和早期的调查人员 阶段研究人员将成像纳入他们的研究工作。