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Long-Term Impact of the COVID-19 Pandemic on Self-Management of Chronic Conditions: The C3 Study

COVID-19 大流行对慢性病自我管理的长期影响：C3 研究

基本信息

批准号：
10630081
负责人：
Stacy C Bailey
金额：
$ 64.73万
依托单位：
NORTHWESTERN UNIVERSITY AT CHICAGO
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-06-01 至 2027-03-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10630081
关键词：
Acute Adherence Adult Affect Age Alcohols Anxiety Authorization documentation Award Biometry COVID-19 COVID-19 impact COVID-19 pandemic effects COVID-19 stress Caring Cessation of life Chicago Chronic Chronic Disease Cohort Studies Collection Communities Data Data Collection Diet Disease Disease Outbreaks Disease Outcome Elderly Electronic Health Record Ethnic Origin Exhibits Fright Gender Grief reaction Health Health Professional Health Status Health behavior Health system Healthcare Individual Infection Infection prevention Intervention Interview Life Style Long COVID Mediating Medical Mental Depression Mental Health Modernization Monitor New York City Outcome Parents Participant Patient Outcomes Assessments Patients Personal Satisfaction Persons Physical activity Policy Maker Prevalence Preventive Health Services Psychosocial Assessment and Care Public Health Race Recommendation Reporting Research Personnel Risk Factors Role Self Efficacy Self Management Site Sleep Sleep disturbances Social Distance Social isolation Social support Socioeconomic Status Stress Surveys Virus Voice Weight Gain authority cohort comorbidity coronavirus disease experience follow up assessment functional status health care service health data health disparity health literacy health management long term consequences of COVID-19 middle age novel outcome disparities pandemic disease pandemic impact physical conditioning physical inactivity pre-pandemic response sex sex disparity socioeconomics substance use telehealth treatment adherence

项目摘要

ABSTRACT We will extend an active NIA cohort study of diverse, middle age and older adults with ≥1 chronic conditions to assess COVID-19’s long-term and disparate impact on health and healthcare experiences. COVID-19 has become an unprecedented public health threat in modern times, especially for older adults with a chronic illness. As of January 2021, 94% of COVID deaths have been among adults over 55; 92% of those who have died had ≥1 underlying health conditions. Beyond consequences to personal health associated with acquiring COVID-19, the impact of the pandemic may likely extend to non-COVID-19 outcomes as a patient’s ability to self-manage chronic conditions during and after a pandemic may be compromised for several reasons. In March 2020, our team rapidly launched the COVID-19 & Chronic Conditions (C3) study as cases of COVID-19 emerged in the U.S. to assess how adults with ≥1 chronic conditions were responding to the pandemic. Five active studies with uniform data collection on a range of patient-reported outcomes prior to COVID-19 and with electronic health records access were leveraged to establish the C3 cohort; 673 adults in Chicago were interviewed during the 1st week of the outbreak. The cohort was immediately expanded using two of the ‘parent studies’ that also had sites in New York City (n=200; N=873). C3 participants are diverse by socioeconomic status, race, ethnicity, gender, health literacy, and comorbidity. An NIA COVID-19 supplement was awarded in August 2020 to expand the cohort via the parent studies (N=1200) and continue data collection up to 2022; 5 of 7 planned survey waves have been completed (83-94% retention). C3 findings reveal many adults exhibit sustained, high stress due to COVID-19 that impacts lifestyle, treatment adherence, and healthcare use. Disparities by sex, race, ethnicity, and SES also are present. Health professionals and researchers are now voicing concern for possible long-term consequences of COVID-19 on personal health & healthcare. In response, we propose to continue to follow the C3 cohort to capture data 5 years post onset of the U.S. outbreak. All participants will have a ‘Pre-COVID’ baseline and 7+ follow-up assessments to assess trajectories in health care use, patient-reported & chronic disease outcomes. Our primary aims are to: 1) evaluate changes in lifestyle, health behaviors, healthcare use, health status, and chronic disease outcomes from a pre-pandemic baseline through 5 years after onset of COVID-19; 2) determine the extent to which stress, anxiety, and depression contribute to poor health status and chronic disease outcomes through 5 years after the pandemic’s onset. Our secondary aim is to: 3) identify factors that mediate or moderate associations between stress, anxiety, and depression during/after the pandemic with health status and chronic disease outcomes, while our exploratory aim is to: 4) explore whether health disparities by age, sex, race, ethnicity, or socioeconomic status emerge or worsen during/after the pandemic and the contributing role of stress, anxiety, and depression.

摘要