Adverse effects of climate change on air pollution, aeroallergen exposures and asthma symptoms

气候变化对空气污染、空气过敏原暴露和哮喘症状的不利影响

• 批准号: 10671351
• 负责人: William Checkley
• 金额: $ 11.39万
• 依托单位: UNIVERSIDAD PERUANA CAYETANO HEREDIA
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-09-28 至 2027-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10671351
• 关键词: Address; Adverse effects; Affect; Air; Air Pollution; Allergic; Altitude; Area; Asthma; Child; Chronic; Chronic Obstructive Pulmonary Disease; Country; Data; Dictyoptera; Disease Outcome; Dust; Evaluation; Frequencies; Geography; Household; Humidity; Hypersensitivity; Link; Location; Meteorology; Modeling; Molds; Monitor; Mus; Particulate Matter; Patient Self-Report; Peru; Positioning Attribute; Prevalence; Reporting; Research; Research Priority; Rhinitis; Risk; Role; Sampling; Severities; Symptoms; Temperature; Time; Urbanization; Variant; Weather; air monitoring; airborne allergen; asthma exacerbation; atmospheric modeling; chronic respiratory disease; climate change; cost; dander; fine particles; improved; innovation; parent grant; peri-urban; pyroglyphid; remote sensing; respiratory; respiratory health; response; urban setting

SUMMARY Climate change may affect chronic respiratory diseases like COPD and asthma by increasing ground-level particulate matter concentrations and aeroallergen exposures through its effects on ambient temperature and other meteorological conditions. It is unclear, however, the degree to which climate change will affect air quality. Also, the links between aeroallergen exposures, ambient temperature, and respiratory health are not well established. Analyses that account for local meteorological conditions at different altitudes need to be developed. We are working to develop better air pollution models in Peru. The parent grant aims to combine ground-level monitors with satellite remote-sensing data across several settings in Peru; however, we only anticipate installing 24 low-cost monitors in Peru. Here we propose to expand the air pollution monitoring network to six monitors per Department, located at different altitudes and at locations with varying degrees of urbanization. A more comprehensive model that allows for greater detail on geographical conditions that include altitude, ambient temperature, relative humidity and degree of urbanization may be constructed through the installation of additional monitors across the different Departments in Peru. By expanding the air pollution monitoring grid for the Peru GeoHealth Hub with an additional 96 monitors, we seek to answer the following important questions about how climate change may adversely affect air pollution, aeroallergen exposures and asthma and allergy symptoms: Whether fine particulate matter (PM2.5) air pollution is affected by variations in ambient temperature and altitude across different regions of Peru and if airborne allergen exposures are affected by ambient temperatures which in turn affects allergic symptoms in Lima, Peru. We seek to address two important areas of research priority in the connection between climate change and air quality. Research that identifies increasing risks from air pollution and airborne allergen exposures because of warmer temperatures can help to better understand the role of climate change on chronic respiratory conditions including COPD and asthma exacerbations.

总结 气候变化可能会通过增加地面水平来影响慢性呼吸道疾病，如COPD和哮喘 通过其对环境温度的影响， 其他气象条件。然而，气候变化对空气的影响程度还不清楚 质量.此外，空气过敏原暴露，环境温度和呼吸系统健康之间的联系并不明确。 很好地建立了。需要对不同海拔的当地气象条件进行分析， 开发我们正在努力在秘鲁开发更好的空气污染模型。家长补助金旨在将联合收割机 在秘鲁的几个地区使用卫星遥感数据进行地面监测;然而，我们只 预计在秘鲁安装24台低成本监测器。在此我们建议扩大空气污染监测 每个部门有六个监测器，分布在不同高度和不同程度的地点， 城镇化一个更全面的模型，允许更详细的地理条件， 包括海拔、环境温度、相对湿度和城市化程度，可以通过 在秘鲁的不同部门安装更多的监测器。通过扩大空气污染 秘鲁GeoHealth中心的监测网格，另外还有96台监测器，我们试图回答以下问题 关于气候变化如何对空气污染、空气过敏原暴露和 哮喘和过敏症状：细颗粒物（PM2.5）空气污染是否受 秘鲁不同地区的环境温度和海拔高度，如果空气中的过敏原暴露 受环境温度的影响，这反过来又会影响秘鲁利马的过敏症状。我们寻求解决 气候变化与空气质量之间的联系是两个重要的研究优先领域。研究 该研究发现，由于气候变暖，空气污染和空气过敏原暴露的风险增加， 温度可以帮助更好地了解气候变化对慢性呼吸道疾病的作用 包括COPD和哮喘恶化。