Administrative Core - EPIC

项目总结 真核病原体在全球范围内造成重大疾病，更多的是在局部地区，威胁到南方公民的健康 卡罗莱纳州和美国东南部。克莱姆森大学在真核病原体研究方面的优势 领导克莱姆森大学董事会批准真核病原体创新的成立 中心(EPIC)于2013年1月。史诗的首要主题是研究具有全球重要性的真核生物。 病原体使用最先进的分子、细胞、生化、遗传、化学、生物物理和基因组 接近了。行政核心建议的具体目标是：(1)继续建设克莱姆森史诗 成为国家和国际公认的研究中心；(2)招聘具有多样化的高素质教师 研究兴趣，以建立临界质量和扩大史诗的广度，以及(3)开发和管理一个 全面的指导计划，以提高目标调查员(TI)在研究和资质方面的成功。 实现这些目标的三个关键办法是：(I)通过雇用更多的 教授和博士后研究人员在真核发病机制领域，并为他们提供 在研究和资质方面提供全面和深入的指导，为他们提供工具 成功竞争NIH R01或同等资金；(Ii)继续主持顶尖研究人员的演讲 在真核病原体细胞生物学会议和中心/系/学院的现场 举办研讨会以提高EPIC的知名度；以及(Iii)加强EPIC和Clemson Light的研究基础设施 成像设备和克莱姆森大学基因组和生物信息学核心设施，以帮助研究 进取号。EPIC行政核心的总体计划与以下承诺相结合 科学学院和克莱姆森大学行政部门将定位EPIC，以真正实现这一地位 生物医学研究卓越中心。

PROJECT SUMMARY Eukaryotic pathogens cause significant disease globally, and more locally, threaten the health of citizens in South Carolina and the Southeastern United States. Clemson University’s strength in eukaryotic pathogens research led the Clemson University Board of Trustees to approve formation of the Eukaryotic Pathogens Innovation Center (EPIC) in January 2013. The overarching theme of EPIC is the study of globally important eukaryotic pathogens using state-of-the-art molecular, cellular, biochemical, genetic, chemical, biophysical, and genomic approaches. The Specific Aims of the Administrative Core proposal are: (1) to continue building Clemson EPIC into a nationally and internationally recognized research center, (2) to recruit high quality faculty with diverse research interests to build critical mass and expand the breadth of EPIC, and (3) to develop and administer a comprehensive mentoring program to enhance Target Investigator (TI) success in research and grantsmanship. Three key approaches to achieving these aims are: (i) expanding the breadth of expertise by hiring additional faculty and postdoctoral researchers in the area of eukaryotic pathogenesis and providing them with comprehensive and intensive mentoring in research and grantsmanship to provide them with the tools to successfully compete for NIH R01 or equivalent funding; (ii) continuing to host presentations by top researchers in the field at the Cellular Biology of Eukaryotic Pathogens meeting and at Center/Departmental/College seminars to raise EPIC’s profile; and (iii) enhancing research infrastructure within EPIC and the Clemson Light Imaging Facility and the Clemson University Genomics and Bioinformatics core facilities to aid in the research enterprise. The overall plan for the EPIC Administrative Core combined with the demonstrated commitment of the College of Science and the Clemson University Administration will position EPIC to truly achieve the status of a Center for Biomedical Research Excellence.