Dementia and Related Health and Social Challenges in Lebanon: A Population Study

黎巴嫩的痴呆症及相关健康和社会挑战：人口研究

• 批准号: 10633203
• 负责人: CARLOS F. MENDES DE LEON
• 金额: $ 67.38万
• 依托单位: GEORGETOWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-15 至 2025-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10633203
• 关键词: Address; Adult; Affect; Age; Aging; Alzheimer' s disease care; Alzheimer' s disease related dementia; Alzheimer' s disease risk; American; Caregivers; Caring; Chronic Disease; Chronic stress; Climacteric; Cognitive; Cohort Studies; Collaborations; Complex; Conflict (Psychology); Country; Data; Dementia; Demographic Transitions; Development; Education; Elderly; Ethnic Origin; Exposure to; Face; Family; Family Relationship; Foundations; Future; Goals; Growth; Health; Healthcare; Impaired cognition; Incidence; Income; Interdisciplinary Study; Intervention Studies; Knowledge; Lebanon; Life; Life Cycle Stages; Long-Term Care; Longitudinal Studies; Longitudinal Surveys; Methods; Michigan; Middle East; Migrant Workers; Modeling; Northern Africa; Observational Study; Older Population; Outcome; Pattern; Politics; Population; Population Research; Population Study; Prevalence; Prevention strategy; Quality of Care; Research; Research Design; Research Methodology; Research Personnel; Resource-limited setting; Resources; Respondent; Risk Factors; Role; Sampling; Series; Social Conditions; Social outcome; Socioeconomic Status; Solid; Structure; Surveys; Techniques; Testing; Training Activity; Universities; Work; aged; aging population; analytical method; caregiving; cognitive interview; cohort; dementia risk; design; epidemiology study; experience; family support; follow-up; informal care; innovation; insight; instrument; interest; low and middle-income countries; novel; population based; population survey; programs; recruit; sex; social; socioeconomics; traditional care; virtual

The overall objective of this application is to build capacity in longitudinal survey research methods and investigate the burden of dementia and related personal, social and health challenges in the older population of Lebanon. Population aging is occurring across the entire world, including in many low- and middle-income countries (LMIC). As a result, these countries face a rapidly growing burden of common age-associated chronic illnesses, including Alzheimer's disease and related dementias (ADRD). Lebanon is a middle-income country in the Middle East North Africa (MENA) region where the prevalence of ADRD is estimated to be among the highest in the world. There is currently very limited reliable information on the prevalence and incidence of ADRD and on the primary ADRD risk factors in this population. Furthermore, LMIC countries like Lebanon often face substantial challenges in the adequate provision of care for ADRD, and very little is known about patterns of formal and informal care for the health and personal needs of affected older adults and their families. There is also insufficient research capacity for the conduct of rigorous studies of ADRD to address the population burden due to ADRD in Lebanon. The proposed project has two over-arching goals. First, it aims to build new research capacity for the conduct of rigorous epidemiological studies of ADRD and other important aging-related health and social outcomes, with particular emphasis on longitudinal research designs and complex sampling strategies. The research capacity activities will be developed and carried out in close collaboration between the investigative teams at the American University of Beirut (AUB) and the University of Michigan, involving a series of training modules that are relevant to the social and cultural context in Lebanon. Second, it aims to develop a new population-based cohort study and recruit a sample of 3,000 adults aged 60 and older who will participate in a structured assessment of dementia, caregiver needs and arrangements, and other health and social domains relevant to understanding the challenges of population aging in Lebanon. The study intends to generate important new information on novel risk factors for ADRD, especially as it relates to the role of prolonged exposure to stressful social conditions throughout the lifecourse. Large segments of the adult population have experienced political instability and conflict that has dominated public life in Lebanon during the last four decades. It will also add important new information on caregiver needs and arrangements, especially as it relates to the growth in the hiring of domestic migrant workers. This model of care for older adults is increasingly replacing more traditional care models that rely on relatives. Findings from this work will not only inform potential strategies to reduce the population burden due to ADRD, but are also expected to increase our understanding of potentially important new risk factors for ADRD and the care arrangements for older adults with ADRD in many other settings and populations around the world.

这项申请的总体目标是建立纵向调查研究方法方面的能力， 调查老年人口中痴呆症的负担以及相关的个人、社会和健康挑战， 黎巴嫩。人口老龄化正在全世界发生，包括许多低收入和中等收入国家。 （LMIC）。因此，这些国家面临着迅速增长的与年龄有关的共同负担。 慢性疾病，包括阿尔茨海默病和相关痴呆症（ADRD）。黎巴嫩是一个中等收入国家 中东北非（MENA）地区的国家，据估计ADRD的患病率为 是世界上最高的。目前关于流行率的可靠信息非常有限， ADRD的发病率和主要ADRD风险因素。此外，像LMIC这样的国家 黎巴嫩在为ADRD提供充分护理方面经常面临巨大挑战，并且知之甚少 关于对受影响老年人的健康和个人需求的正式和非正式护理模式及其 家庭也没有足够的研究能力对ADRD进行严格的研究，以解决 黎巴嫩ADRD造成的人口负担。拟议的项目有两个首要目标。首先，它旨在 建立新的研究能力，对ADRD和其他重要疾病进行严格的流行病学研究 与老龄化有关的健康和社会结果，特别强调纵向研究设计， 复杂的抽样策略。研究能力活动将在密切合作下制定和开展。 贝鲁特美国大学（AUB）和贝鲁特大学的调查小组之间的合作 密歇根大学，涉及一系列与黎巴嫩社会和文化背景有关的培训单元。 其次，它旨在开发一项新的基于人群的队列研究，并招募3,000名60岁的成年人作为样本 和老年人谁将参与痴呆症，照顾者的需求和安排的结构化评估， 与理解黎巴嫩人口老龄化挑战相关的其他卫生和社会领域。的 这项研究旨在产生关于ADRD新风险因素的重要新信息，特别是因为它涉及 在整个生命过程中长期暴露于紧张的社会条件的作用。很大一部分 在黎巴嫩，成年人经历了主导公共生活的政治不稳定和冲突 在过去的四十年里。它还将增加关于照顾者需求和安排的重要新信息， 特别是因为它涉及到雇用移徙家庭佣工的增长。这种照顾老年人的模式 成年人越来越多地取代了依赖亲属的传统护理模式。这项工作的结果将 不仅为减少ADRD造成的人口负担的潜在战略提供信息，而且预计还将 增加我们对ADRD潜在的重要新风险因素的理解， 在世界各地的许多其他环境和人群中患有ADRD的老年人。