Administrative Core
行政核心
基本信息
- 批准号:10697366
- 负责人:
- 金额:$ 35.67万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2022
- 资助国家:美国
- 起止时间:2022-09-15 至 2027-08-31
- 项目状态:未结题
- 来源:
- 关键词:Academic Medical CentersAgreementBasic ScienceBiological SciencesCancer CenterCenter for Translational Science ActivitiesCollaborationsColonCommunicationDataData Coordinating CenterDevelopmentEnsureEnvironmentEpitheliumEvaluationExpenditureFeedbackFosteringFundingHumanInfrastructureInstitutionInterdisciplinary StudyLeadLeadershipLesionModelingParticipantPlayPoliciesProceduresProcessRegulationReportingResearchResearch DesignResource SharingRoleScienceSecureShapesSystemTissue atlasTranslational ResearchUnited States National Institutes of HealthUniversitiesVisionWorkdata exchangedata sharingexperiencehuman tissueimprovedmembermicrobiotamultidisciplinaryoperationorganizational structurepremalignantprogramsrecruitresearch data disseminationsuccesstool
项目摘要
PROJECT SUMMARY/ABSTRACT: Administrative Core
The leadership of the Vanderbilt University Medical Center TBEL Center builds on an existing multidisciplinary
team that has been working together for over 15 years on the Vanderbilt-Ingram Cancer Center (VICC) GI
Special Programs of Research Excellence (SPORE), as well as the Human Tissue Atlas Network (HTAN) that
has been in existence for four years. We have also recruited Dr. Cynthia Sears from Johns Hopkins to round out
expertise for this application. Each team member also has extensive experience in collaborative research efforts
across multiple studies and multiple institutions. The Administrative Core will provide the primary scientific
oversight for the Vanderbilt TBEL activities. It will have primary management and oversight responsibility for all
TBEL activities, which include reviewing and regulating financial expenditures, creating and preparing necessary
reports, internal and external communications, research coordination, and ensuring compliance with all federal
regulations and reporting requirements (including NIH public access policy). Thus, the Administrative Core
directly supports all members and organizational components of the TBEL Center, including the three Projects
and the two Cores - the Human Pre-Cancer Models (HPM) Core and the Quantitative Bioscience Core (QBC).
The Administrative Core will coordinate collaborations with NCI and other TBEL Centers. Our team has extensive
experience working within NCI-funded networks. As the funded TBEL Centers are developed, there will be
multiple opportunities to find shared aims and potential new collaborative projects in which the Vanderbilt TBEL
will enthusiastically participate and even lead. The Administrative Core will also ensure full compliance with the
data and resource sharing plans agreed upon with NCI and the TBEL Centers. This will be accomplished by
working closely with the QBC to ensure that all relevant data and tools are transferred securely and in a timely
manner to the TBEL data coordinating center. During the initial development of the TBEL Center, the Project
and Core Leads and Co-Leads will work closely with NCI and the other TBEL Centers. Based on our past
experience and present shared vision, we are fully committed to the success of the TBEL Center.
项目摘要/摘要:行政核心
范德比尔特大学医学中心的领导建立在现有的多学科基础上
在范德比尔特-英格拉姆癌症中心(VICC)GI上合作了15年以上的团队
卓越研究特别计划(孢子),以及人体组织图谱网络(Htan),
已经存在了四年了。我们还聘请了约翰·霍普金斯大学的辛西娅·西尔斯博士来完善
此应用程序的专业知识。每个团队成员都有丰富的合作研究经验。
跨多个研究和多个机构。行政核心将提供主要的科学依据
对范德比尔特的活动进行监督。它将对所有人负有主要管理和监督责任
Tbel活动,包括审查和管理财务支出,制定和准备必要的
报告、内部和外部沟通、研究协调,并确保遵守所有联邦
法规和报告要求(包括NIH公共访问政策)。因此,行政核心
直接支持TBEL中心的所有成员和组织组成部分,包括三个项目
以及两个核心--人类癌前模型(HPM)核心和定量生物科学核心(QBC)。
管理核心将协调与NCI和其他TBEL中心的合作。我们的团队有广泛的
有在NCI资助的网络中工作的经验。随着资助的Tbel中心的发展,将会有
找到共同目标和潜在的新合作项目的多个机会,范德比尔特家族在这些项目中
会热情参与,甚至带头。行政核心还将确保完全遵守
与NCI和TBEL中心商定的数据和资源共享计划。这将通过以下方式实现
与QBC密切合作,确保所有相关数据和工具安全、及时地转移
TBEL数据协调中心的处理方式。在TBEL中心的最初开发过程中,该项目
核心导联和联合导联将与NCI和其他TBEL中心密切合作。基于我们的过去
经验和现在的共同愿景,我们完全致力于TBEL中心的成功。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Martha J. Shrubsole其他文献
Erratum to: Urinary polyphenols and breast cancer risk: results from the Shanghai Women’s Health Study
- DOI:
10.1007/s10549-009-0599-3 - 发表时间:
2009-10-25 - 期刊:
- 影响因子:3.000
- 作者:
Jianfeng Luo;Yu-Tang Gao;Wong-Ho Chow;Xiao-Ou Shu;Honglan Li;Gong Yang;Qiuyin Cai;Nathaniel Rothman;Hui Cai;Martha J. Shrubsole;Adrian A. Franke;Wei Zheng;Qi Dai - 通讯作者:
Qi Dai
Sa1113: A SINGLE-CELL RESOLUTION, MULTI-OMIC SPATIAL ATLAS OF COLONIC TUMORIGENESIS DRIVEN BY <em>C. DIFFICILE</em> FROM HUMAN COLORECTAL CANCER-ASSOCIATED BIOFILMS
- DOI:
10.1016/s0016-5085(22)60740-6 - 发表时间:
2022-05-01 - 期刊:
- 影响因子:
- 作者:
Nicholas O. Markham;Julia L. Drewes;Jada C. Domingue;Bob Chen;Cody N. Heiser;Molly A. Bingham;Alan J. Simmons;Marisol A. Ramirez;Subhag Kotrannavar;Hannah Lunnemann;Erin Laubacher;Won Jae Huh;Martha J. Shrubsole;Qi Liu;Robert Coffey;Cynthia L. Sears;Ken S. Lau - 通讯作者:
Ken S. Lau
Tissue gene expression analysis approach in a context of high technical and biological heterogeneity
- DOI:
10.1186/s13104-025-07383-0 - 发表时间:
2025-07-22 - 期刊:
- 影响因子:1.700
- 作者:
Evan Bagley;Souvik Seal;Lauren R. Fanning;Jean-Sebastien Anoma;Tami Crawford;Benjamin G. Vincent;Elizabeth L. Barry;Martha J. Shrubsole;Erin Kirk;John A. Baron;Dale C. Snover;David N. Lewin;Todd A. Mackenzie;Xiaohua Gao;Melissa A. Troester;Alexander V. Alekseyenko;Kristin Wallace - 通讯作者:
Kristin Wallace
Sa1227 BACTERIAL INVASION IN PRECANCEROUS POLYPS FROM THE COLON MOLECULAR ATLAS PROJECT
- DOI:
10.1016/s0016-5085(23)01760-2 - 发表时间:
2023-05-01 - 期刊:
- 影响因子:
- 作者:
Uswah Siddiqi;Julia L. Drewes;Cynthia L. Sears;Robert J. Coffey;Ken S. Lau;Martha J. Shrubsole;Nicholas O. Markham - 通讯作者:
Nicholas O. Markham
Assessing the role of the gut microbiome at the interface between environmental chemical exposures and human health: Current knowledge and challenges
- DOI:
10.1016/j.envpol.2022.120380 - 发表时间:
2022-12-15 - 期刊:
- 影响因子:7.300
- 作者:
Anna Maria Campana;Hannah E. Laue;Yike Shen;Martha J. Shrubsole;Andrea A. Baccarelli - 通讯作者:
Andrea A. Baccarelli
Martha J. Shrubsole的其他文献
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{{ truncateString('Martha J. Shrubsole', 18)}}的其他基金
Colibactin-Producing Escherichia coli as an Environmental Stimulus Shaping Pre-Cancer Progression
产生大肠杆菌素的大肠杆菌作为塑造癌症前期进展的环境刺激物
- 批准号:
10518848 - 财政年份:2022
- 资助金额:
$ 35.67万 - 项目类别:
Colibactin-Producing Escherichia coli as an Environmental Stimulus Shaping Pre-Cancer Progression
产生大肠杆菌素的大肠杆菌作为塑造癌症前期进展的环境刺激物
- 批准号:
10697373 - 财政年份:2022
- 资助金额:
$ 35.67万 - 项目类别:
Effect of magnesium treatment on vitamin D resistance
镁治疗对维生素 D 抵抗的影响
- 批准号:
9248761 - 财政年份:2016
- 资助金额:
$ 35.67万 - 项目类别:
Methionine metabolism in esophageal adenocarcinoma carcinogenesis
食管腺癌癌变过程中的蛋氨酸代谢
- 批准号:
9193068 - 财政年份:2016
- 资助金额:
$ 35.67万 - 项目类别:
Methionine metabolism in esophageal adenocarcinoma carcinogenesis
食管腺癌癌变过程中的蛋氨酸代谢
- 批准号:
9024964 - 财政年份:2015
- 资助金额:
$ 35.67万 - 项目类别:
Reproducibility and validity of microbiomial markers in colorectal cancer
结直肠癌微生物标志物的重现性和有效性
- 批准号:
8639073 - 财政年份:2014
- 资助金额:
$ 35.67万 - 项目类别:
Reproducibility and validity of microbiomial markers in colorectal cancer
结直肠癌微生物标志物的重现性和有效性
- 批准号:
8788702 - 财政年份:2014
- 资助金额:
$ 35.67万 - 项目类别:
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