One session treatment for dental phobia in an underserved population
服务欠缺人群的牙科恐惧症的一次疗程治疗
基本信息
- 批准号:10698001
- 负责人:
- 金额:$ 31.58万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2022
- 资助国家:美国
- 起止时间:2022-09-06 至 2024-08-31
- 项目状态:已结题
- 来源:
- 关键词:AddressAdherenceAdolescenceAdolescentAdultAffectAgeAnxietyAnxiety DisordersAppearanceAreaAutomobile DrivingAwardBasic ScienceChildChildhoodClinicClinicalClinical ResearchClinical TrialsCommunitiesControlled StudyCountryDataData CollectionDentalDental AnxietyDental CareDental ClinicsDental HygienistsDental OfficesDentistsDevelopmentDietDiseaseDissemination and ImplementationDocumentationEatingEnsureEtiologyEvidence based treatmentFamilyFeasibility StudiesFrightFutureGoalsGood Clinical PracticeGrantHealth ProfessionalHealthcareHispanicHispanic PopulationsIndividualInterdisciplinary StudyInterruptionInterventionIntervention StudiesKnowledgeLabelLaboratoriesLatinoLearningLiteratureLow incomeMeasuresMediatingMediatorMedicalNational Institute of Dental and Craniofacial ResearchOdontogenesisOralOral healthPainParticipantPatient RecruitmentsPhasePhobiasPrediction of Response to TherapyPrevalenceProceduresQuality of lifeRandomizedRelaxation TherapySamplingShameSpecific PhobiaTestingTooth structureTreatment outcomeUnderserved PopulationUnited StatesWorkYouthacceptability and feasibilityactive controlanxiousbehavioral clinical trialchildhood anxietyclinical research sitecommunity settingcomparative efficacyeffective therapyefficacious treatmentefficacy evaluationexperiencehigh riskimplementation effortsparticipant retentionpatient responsepsychoeducationpsychoeducationalrecruitretention ratesocialstandard of caresuccesstheoriestreatment armtreatment effecttrial comparing
项目摘要
PROJECT SUMMARY/ABSTRACT
Dental phobia is associated with avoidance of proper dental care, poor dental health, and decrements in social
and oral quality of life. Although dental phobia may persist for many years, the disorder usually first manifests
during childhood or adolescence. Hispanic youth may be at particularly high risk of developing dental phobia
because Hispanic/Latino families are less likely to take a preventative stance toward dental health. This means
that Hispanic youths’ first encounters with a dentist are more likely to be for treatment that is associated with
pain, discomfort, or shame – the types of learning experiences related to the development of dental phobia.
Although our knowledge about the etiology of dental phobia is well developed, we know considerably less about
how to treat dental phobia in youth. Recently, a one-session exposure therapy treatment (OST) for specific
phobias has proven successful in addressing a variety of phobias in children and adolescents. However, youth
with dental/medical phobias have not been included in the trials assessing OST because of the need to include
dental health professionals in the treatment. Therefore, the primary goal of this application is to prepare for
and conduct a Stage III trial comparing OST for dental phobia in children and adolescents to an active control
treatment in a predominantly Hispanic population and to examine inhibitory learning as the mechanism
responsible for changes in anxiety and fear. The aims of the UG3 phase are to do the preparatory work needed
for the trial, including the development of all study documentation and finalizing the clinical sites. Additional
plans during the UG3 phase include the assessment of the acceptability and feasibility of the study procedures
and a trial examining whether youth treated with OST show evidence of changes in inhibitory learning. The
primary aim of the UH3 stage is to examine the efficacy of OST in a Stage III social/behavioral clinical trial in
which OST is delivered by dental hygienists. This trial would randomize dental clinics to one of the two
treatment arms (OST vs. Control) so that patient response and the hypothesized mechanism of treatment can
be assessed. Factors related to future dissemination and implementation efforts will also be examined. It is
hypothesized that OST can provide an efficacious treatment option that can be delivered by hygienists in the
dental office. That is, that the treatment can decrease both anxiety and phobic avoidance in youth. Moreover,
although exposure therapy has a high level of empirical support in youth and a good deal of laboratory work
has been conducted to develop the theory to explains its effects, the main hypothesized mechanism of action –
inhibitory learning – has not been studied as a mediator within the context of a clinical trial; therefore, this
work could advance our understanding of the mechanism driving one of the most promising treatments for
individuals with anxiety disorders.
项目总结/摘要
牙科恐惧症与避免适当的牙科护理,牙齿健康状况差以及社交能力下降有关。
和口腔生活质量。虽然牙科恐惧症可能会持续多年,但这种疾病通常首先表现为
在童年或青春期。西班牙裔年轻人患牙科恐惧症的风险特别高
因为西班牙裔/拉丁裔家庭不太可能对牙齿健康采取预防措施。这意味
西班牙裔年轻人与牙医的第一次接触更有可能是为了治疗与
疼痛、不适或羞耻--与牙科恐惧症发展相关的学习经历类型。
虽然我们对牙科恐惧症的病因学的知识是发达的,我们知道相当少,
如何治疗青少年的牙科恐惧症最近,一个疗程的暴露疗法治疗(OST)的具体
事实证明,“恐惧症”在解决儿童和青少年的各种恐惧症方面是成功的。然而,青年
牙科/医疗恐惧症患者没有被纳入评估OST的试验中,因为需要纳入
牙科保健专业人员在治疗。因此,本应用程序的主要目标是为
并进行第三阶段试验,比较OST对儿童和青少年牙齿恐惧症的治疗效果和积极控制效果。
治疗在一个主要的西班牙裔人口,并检查抑制性学习的机制,
负责焦虑和恐惧的变化。UG 3阶段的目标是完成所需的准备工作
包括所有研究文件的开发和临床研究中心的最终确定。额外
UG 3阶段的计划包括评估研究程序的可接受性和可行性
还有一项试验,检验接受OST治疗的年轻人是否表现出抑制性学习的变化。的
UH 3阶段的主要目的是在III期社会/行为临床试验中检查OST的疗效,
而OST是由牙科医生提供的。这项试验将牙科诊所随机分为两个
治疗组(OST与对照组),以便患者反应和假设的治疗机制可以
进行评估。还将审查与今后的传播和执行工作有关的因素。是
假设OST可以提供一种有效的治疗选择,
牙科诊所也就是说,这种治疗可以减少年轻人的焦虑和恐惧回避。此外,委员会认为,
尽管暴露疗法在青年中有很高的经验支持,
已经进行了发展的理论,以解释其影响,主要的假设机制的行动-
抑制性学习-尚未在临床试验的背景下作为中介进行研究;因此,
这项工作可以促进我们对驱动最有希望的治疗方法之一的机制的理解。
焦虑症患者
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
THOMAS H. OLLENDICK其他文献
THOMAS H. OLLENDICK的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('THOMAS H. OLLENDICK', 18)}}的其他基金
One session treatment for dental phobia in an underserved population
服务欠缺人群的牙科恐惧症的一次疗程治疗
- 批准号:
10348505 - 财政年份:2022
- 资助金额:
$ 31.58万 - 项目类别:
Attention Training for Adolescents with Soical Anxiety Disorder
患有社交焦虑症的青少年的注意力训练
- 批准号:
8509339 - 财政年份:2013
- 资助金额:
$ 31.58万 - 项目类别:
Attention Training for Adolescents with Soical Anxiety Disorder
患有社交焦虑症的青少年的注意力训练
- 批准号:
8821666 - 财政年份:2013
- 资助金额:
$ 31.58万 - 项目类别:
Attention Training for Adolescents with Soical Anxiety Disorder
患有社交焦虑症的青少年的注意力训练
- 批准号:
8656440 - 财政年份:2013
- 资助金额:
$ 31.58万 - 项目类别:
Modification of Interpretation Bias for Intergenerational Anxiety Tranmission
代际焦虑传递的解释偏差的修正
- 批准号:
8243270 - 财政年份:2012
- 资助金额:
$ 31.58万 - 项目类别:
Modification of Interpretation Bias for Intergenerational Anxiety Tranmission
代际焦虑传递的解释偏差的修正
- 批准号:
8423683 - 财政年份:2012
- 资助金额:
$ 31.58万 - 项目类别:
Mediators, Moderators and Treatment Outcomes with Oppositional Defiant Disorder
对立违抗障碍的调解者、调节者和治疗结果
- 批准号:
7414573 - 财政年份:2007
- 资助金额:
$ 31.58万 - 项目类别:
Mediators, Moderators and Treatment Outcomes with Oppositional Defiant Disorder
对立违抗障碍的调解者、调节者和治疗结果
- 批准号:
7813785 - 财政年份:2007
- 资助金额:
$ 31.58万 - 项目类别:
Mediators, Moderators and Treatment Outcomes with Oppositional Defiant Disorder
对立违抗障碍的调解者、调节者和治疗结果
- 批准号:
7242313 - 财政年份:2007
- 资助金额:
$ 31.58万 - 项目类别:
Mediators, Moderators and Treatment Outcomes with Oppositional Defiant Disorder
对立违抗障碍的调解者、调节者和治疗结果
- 批准号:
8063094 - 财政年份:2007
- 资助金额:
$ 31.58万 - 项目类别:
相似海外基金
An innovative, AI-driven prehabilitation platform that increases adherence, enhances post-treatment outcomes by at least 50%, and provides cost savings of 95%.
%20创新、%20AI驱动%20康复%20平台%20%20增加%20依从性、%20增强%20治疗后%20结果%20by%20at%20至少%2050%、%20和%20提供%20成本%20节省%20of%2095%
- 批准号:
10057526 - 财政年份:2023
- 资助金额:
$ 31.58万 - 项目类别:
Grant for R&D
Improving Repositioning Adherence in Home Care: Supporting Pressure Injury Care and Prevention
提高家庭护理中的重新定位依从性:支持压力损伤护理和预防
- 批准号:
490105 - 财政年份:2023
- 资助金额:
$ 31.58万 - 项目类别:
Operating Grants
I-Corps: Medication Adherence System
I-Corps:药物依从性系统
- 批准号:
2325465 - 财政年份:2023
- 资助金额:
$ 31.58万 - 项目类别:
Standard Grant
Unintrusive Pediatric Logging Orthotic Adherence Device: UPLOAD
非侵入式儿科记录矫形器粘附装置:上传
- 批准号:
10821172 - 财政年份:2023
- 资助金额:
$ 31.58万 - 项目类别:
Nuestro Sueno: Cultural Adaptation of a Couples Intervention to Improve PAP Adherence and Sleep Health Among Latino Couples with Implications for Alzheimer’s Disease Risk
Nuestro Sueno:夫妻干预措施的文化适应,以改善拉丁裔夫妇的 PAP 依从性和睡眠健康,对阿尔茨海默病风险产生影响
- 批准号:
10766947 - 财政年份:2023
- 资助金额:
$ 31.58万 - 项目类别:
CO-LEADER: Intervention to Improve Patient-Provider Communication and Medication Adherence among Patients with Systemic Lupus Erythematosus
共同领导者:改善系统性红斑狼疮患者的医患沟通和药物依从性的干预措施
- 批准号:
10772887 - 财政年份:2023
- 资助金额:
$ 31.58万 - 项目类别:
Pharmacy-led Transitions of Care Intervention to Address System-Level Barriers and Improve Medication Adherence in Socioeconomically Disadvantaged Populations
药房主导的护理干预转型,以解决系统层面的障碍并提高社会经济弱势群体的药物依从性
- 批准号:
10594350 - 财政年份:2023
- 资助金额:
$ 31.58万 - 项目类别:
Antiretroviral therapy adherence and exploratory proteomics in virally suppressed people with HIV and stroke
病毒抑制的艾滋病毒和中风患者的抗逆转录病毒治疗依从性和探索性蛋白质组学
- 批准号:
10748465 - 财政年份:2023
- 资助金额:
$ 31.58万 - 项目类别:
Improving medication adherence and disease control for patients with multimorbidity: the role of price transparency tools
提高多病患者的药物依从性和疾病控制:价格透明度工具的作用
- 批准号:
10591441 - 财政年份:2023
- 资助金额:
$ 31.58万 - 项目类别:
Development and implementation of peer-facilitated decision-making and referral support to increase uptake and adherence to HIV pre-exposure prophylaxis in African Caribbean and Black communities in Ontario
制定和实施同行协助决策和转介支持,以提高非洲加勒比地区和安大略省黑人社区对艾滋病毒暴露前预防的接受和依从性
- 批准号:
491109 - 财政年份:2023
- 资助金额:
$ 31.58万 - 项目类别:
Fellowship Programs