Genomic Research and Data Science Center for Computation and Cloud-Computing

基因组研究和数据科学计算和云计算中心

• 批准号: 10672802
• 负责人: Christopher Doss
• 金额: $ 147.63万
• 依托单位: NORTH CAROLINA AGRI & TECH ST UNIV
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-01 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10672802
• 关键词: Acceleration; Address; Agriculture; Area; Awareness; Biology; Cloud Computing; Companions; Complex; Data Science; Databases; Development; Discipline; Diverse Workforce; Education; Educational Materials; Educational process of instructing; Educational workshop; Environment; Faculty; Funding; Future; Generations; Genomics; Goals; High Performance Computing; Historically Black Colleges and Universities; Institution; Medicine; Minority-Serving Institution; North Carolina; Population; Research; Research Personnel; Research Training; Resources; Science; Scientist; Site; Societies; Students; Systems Biology; Talents; Teacher Professional Development; Technology; Testing; Training; Training and Education; Trust; Underserved Population; United States National Institutes of Health; Universities; Work; career preparation; cloud based; computational platform; computing resources; education resources; hands on research; hands-on learning; health disparity; innovation; instrumentation; interest; learning materials; marginalized community; marginalized population; minority student; open source; recruit; student training; success; symposium; underserved students; university student; webinar

The post-genomic era has transformed biology, medicine and biomedical sciences with this advancement being increasingly driven by ready access to interdisciplinary collaborative technology-driven databases built within the accelerating convergence of computational genomics, data sciences, and cloud computing. There is an urgent need for training the upcoming generation of scientific researchers in this area and effectively drawing upon our nationwide talent pool. Yet, there remains a distinctive STEM and diversity gap in today’s biomedical workforce and associated need for transformative change in training in computational genomics, data sciences, and cloud computing (CGDSCC) to recruit historically marginalized populations. CGDSCC student and faculty training has been limited among historically black colleges and universities (HBCU) and minority student serving (MSI) institutions. This is due to a lack of organized resources such as faculty trained in these disciplines, adequate computing resources, and the instrumentation for conducting genomic research needed to achieve impactful hands-on CGDSCC student training. In this proposal we seek to provide the educational and hands- on research training and resources in computational genomics, data sciences, and cloud computing for the future workforce, particularly among underserved student populations at North Carolina Agricultural and Technical State University and other target HBCU/MSI institutions. We have partnered with 3 HBCU’s, North Carolina Central University, Winston Salem State University and Shaw University, as initial site/target institutions. Additional sites will be recruited if this proposal is funded. Through the creation of the Genomic Research and Data Science Center for Computation and Cloud-Computing (GRADS-4C) we will develop and disseminate cloud-based CGDSCC instructional materials produced with our GRADS-4C affiliated faculty to Target Institutions. This will be accomplished through the establishment of lasting partnerships with target institutions interested in education, facilitation of faculty development and student educational and research training in CGDSCC. We shall also develop and disseminate additional cloud based open source CGDSCC educational resources that can be used with NIH workflows for the Target Institutions. We are particularly well-prepared to undertake the proposed work due to the unique team of expert scientists, educators, collaborators, and advisors we have assembled. This innovative work seeks to formally train the future workforce from underserved populations at minority institutions in cutting edge CGDS and cloud computing education and hand-on research which has not been attempted or accomplished before particularly with MSI’s as lead institution. Successful completion of this project will be of high significance, since it will boost greater overall capacity and critical engagement from an expanded, more diverse workforce ready to solve complex biomedical/society problems requiring and benefitting from CGDSCC approaches. 1

基因组时代已经改变了生物学，医学和生物医学科学，这种进步是 越来越多地驱动着跨学科协作技术驱动的数据库的驱动 计算基因组学，数据科学和云计算的加速收敛。有紧急 需要培训即将到来的该领域的科学研究人员，并有效地利用我们的 全国人才库。但是，在当今的生物医学劳动力中仍然存在独特的茎和多样性差距 以及对计算基因组学，数据科学和云的培训训练的变化的相关需求 计算（CGDSCC）以招募历史上边缘化的人群。 CGDSCC的学生和教师培训已有 在历史上的黑人学院和大学（HBCU）和少数民族学生服务（MSI）中受到限制 机构。这是由于缺乏有组织的资源，例如在这些学科中训练的教师，足够 计算资源以及进行基因组研究的仪器，以实现有影响力 动手CGDSCC学生培训。在此提案中，我们寻求提供教育和动手 - 关于计算基因组学，数据科学和云的研究培训和资源 未来劳动力的计算，尤其是在服务不足的学生人数中 北卡罗来纳州农业和技术州立大学以及其他目标HBCU/MSI 机构。我们已经与北卡罗来纳州中央大学的3 HBCU合作，温斯顿·塞勒姆州立大学 大学和肖大学，作为初始地点/目标机构。如果此，将招募其他网站 提案是资助的。通过创建基因组研究和数据科学计算中心 和云计算（Grads-4C）我们将开发并传播基于云的CGDSCC指令 我们的毕业生4C会员教师生产的材料针对目标机构。这将完成 通过与对教育感兴趣的目标机构建立持久的伙伴关系， CGDSCC的教师发展和学生教育与研究培训。我们还将发展和 传播可以与NIH一起使用的其他基于云的开源CGDSC教育资源 目标机构的工作流程。由于 我们组装的独特专家科学家，教育者，合作者和顾问团队。这种创新 工作旨在正式从少数族裔机构服务不足的人口中正式培训未来的劳动力 尚未尝试或 特别是在MSI担任领导机构之前完成。成功完成该项目将是 高意义，因为它将提高整体能力和更大的关键参与，从 多样化的劳动力准备解决需要CGDSC的复杂生物医学/社会问题 方法。 1