Multi-institutional, Linked EHRS to Examine Factors and Diagnostic Pathways that Facilitate Early Ovarian Cancer Diagnosis

多机构、关联的 EHRS 检查促进卵巢癌早期诊断的因素和诊断途径

• 批准号: 10676941
• 负责人: GREGORY Michael REBCHOOK
• 金额: $ 24.95万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-30 至 2024-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10676941
• 关键词: Multi; institutional; Linked; EHRS; Examine

Abstract To respond to the HIV epidemic and reduce health disparities in HIV incidence and outcomes, we propose a Prevention Research Center (PRC) at the University of California, San Francisco (UCSF) that facilitates significant and innovative health science research through partnerships with public health colleagues that ultimately improves public health. The HIV epidemic continues to be a major public health crisis in the U.S., with more than 1 million people living with HIV and more than 50,000 becoming newly infected every year. Given the progress in preventing and treating HIV, the Centers for Disease Control and Prevention (CDC) has identified HIV as a winnable battle, Healthy People 2020 has included HIV as a topic area, sexual health is part of the National Prevention Strategy, and United States has released the National HIV/AIDS Strategy. HIV has had a disproportionate impact on African Americans and transgender women, representing one of the largest health disparities in the U.S. While comprising just 13% of the total national population, African Americans account for 51% of all new HIV/AIDS diagnoses. The rate of new HIV infections is particularly profound for transgender women. About a quarter (22-28%) of transgender women are living with HIV, representing 34 times the odds of infection compared to the general population. More than half (about 56%) of African American transgender women are living with HIV. These data highlight the urgent need to focus research on eliminating HIV health disparities among African Americans in general and transgender women in particular. This application proposes to develop and implement authentic community engagement and a support implementation research project that focuses prevention HIV by linking, engaging and reengaging in care transgender women living with HIV. Our overall aims are to: 1. Maintain the multi-disciplinary UCSF PRC to catalyze high-quality applied health promotion and HIV prevention research; 2. Increase availability of evidence-based strategies, interventions, and implementation tools and facilitate innovative, high-impact, multidisciplinary HIV research and knowledge dissemination to address the HIV epidemic; 3. Develop and maximize the public health impact of optimally efficacious, culturally responsive, and implementable interventions, strategies, and prevention tools by moving them into policy and practice; 4. To conduct an applied public health prevention research project, using a community engaged approach, that addresses the significant health disparity in HIV among transgender women; and The PRC will include an administrative infrastructure, a community partnerships core, a dissemination and translation core, and an evaluation core. The work of the cores will be leveraged to reduce significant HIV- related health disparities and strengthen public health programs and practice.

摘要 为了应对艾滋病毒流行病，减少艾滋病毒发病率和结果的健康差距，我们提出了一个 预防研究中心（PRC）在加州大学，旧金山弗朗西斯科（UCSF），促进 通过与公共卫生同事的伙伴关系， 最终改善公众健康。艾滋病毒流行仍然是美国的一个主要公共卫生危机， 每年有100多万人感染艾滋病毒，5万多人新感染。 鉴于预防和治疗艾滋病毒的进展，疾病控制和预防中心（CDC）已 将艾滋病毒确定为一场可以赢得的战斗，2020年健康人将艾滋病毒作为一个主题领域，性健康是其中的一部分 国家预防战略，美国发布了国家艾滋病毒/艾滋病战略。艾滋病毒 对非洲裔美国人和变性妇女的影响不成比例， 虽然非洲裔美国人只占全国总人口的13%，但他们的健康状况却不一样。 占所有艾滋病毒/艾滋病新诊断的51%。新的艾滋病毒感染率对以下国家的影响特别深远： 变性女性大约四分之一（22-28%）的跨性别女性感染了艾滋病毒，占34% 感染几率是普通人群的两倍超过一半（约56%）的非洲人 美国跨性别女性感染艾滋病毒。这些数据突出表明，迫切需要集中研究 消除非裔美国人，特别是变性妇女之间的艾滋病毒健康差距。 该应用程序建议开发和实施真实的社区参与和支持 实施研究项目，重点是通过联系、参与和重新参与护理来预防艾滋病毒 感染艾滋病毒的变性妇女。我们的总体目标是： 1.保持多学科的UCSF PRC，以促进高质量的应用健康促进和艾滋病毒 预防研究; 2.增加循证战略、干预措施和执行工具的可用性，并促进 创新的，高影响力的，多学科的艾滋病毒研究和知识传播，以解决艾滋病毒 流行病; 3.发展和最大限度地发挥最有效的、文化上敏感的、 * 将可实施的干预措施、战略和预防工具纳入政策和实践; 4.采用社区参与的方式，进行一项应用公共卫生预防研究计划， 解决跨性别妇女在艾滋病毒方面的重大健康差距; PRC将包括一个行政基础设施、一个社区伙伴关系核心、一个传播和 翻译核心和评估核心。核心的工作将被用来减少艾滋病毒的重大影响， 相关的健康差距，并加强公共卫生方案和做法。