mHealth Intervention to Increase Uptake of Contraception and PrEP Among Female University Students in Zambia
移动医疗干预措施提高赞比亚女大学生对避孕和 PrEP 的采用率
基本信息
- 批准号:10673744
- 负责人:
- 金额:$ 17.95万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2022
- 资助国家:美国
- 起止时间:2022-08-01 至 2024-07-31
- 项目状态:已结题
- 来源:
- 关键词:AIDS preventionAdolescentAdultAfrica South of the SaharaAfricanAuthorization documentationAwarenessBehavioralBehavioral MechanismsBiological FactorsCaringCause of DeathClinicCommunicationContraceptive AgentsContraceptive AvailabilityContraceptive UsageContraceptive methodsCounselingCountryDataEducationEffectiveness of InterventionsEnsureEventFaceFemaleFemale AdolescentsFutureGovernmentHIVHIV InfectionsHealthHybridsIntentionInterventionInterviewInvestmentsKnowledgeLesothoLevel of EvidenceLifeLife Change EventsLinkLow PrevalenceMediationMethodsMobile Health ApplicationModelingModernizationNotificationOralOutcomeOutcome StudyParticipantPathway interactionsPerceptionPerformancePhasePopulationPredispositionPregnancyPregnancy ComplicationsPreventionPublic HealthQualitative MethodsQuality of lifeRecommendationReproductive HealthReproductive Health ServicesResearchRiskRunningSelf EfficacyServicesSexual HealthSiteStudentsSurveysTabletsTestingUniversitiesVisitZambiaage groupagedarmauthoritydesigneffectiveness evaluationeffectiveness-implementation RCTexperiencefollow-uphealth beliefhealth service usehigh riskhigh-risk adolescentshuman centered designimplementation determinantsimplementation evaluationimprovedinnovationlow and middle-income countriesmHealthmembermortalitynavigator interventionneglectnovelpeerpeer supportpre-exposure prophylaxispreferencepreventprimary outcomeprogramsprospectiverandomized trialreproductivereproductive health interventionreproductive outcomescale upsecondary outcomeservice deliverysexual health interventionsocialsocial factorssocial stigmastructural determinantstheoriestoolunintended pregnancyuniversity studentuptakeyoung woman
项目摘要
Project Summary/Abstract
HIV infection and unintended pregnancy are highly prevalent, life-altering events among adolescent girls and
young women in low- and middle-income countries. Due to a number of biological, social, and structural factors,
adolescent girls and young women in sub-Saharan Africa remain the sub-population most susceptible to HIV
infection. Further, the majority of pregnancies among adolescent girls and young women occur in low- and
middle-income countries with the highest rates found in sub-Saharan Africa. In Zambia, female university
students are a neglected, high-risk sub-population for both HIV infection and unintended pregnancy. Oral pre-
exposure prophylaxis (PrEP) and modern contraception are key biomedical prevention tools but increasing the
uptake among young women in sub-Saharan Africa has proven challenging. Based on preliminary research, we
propose to design a novel peer navigator PrEP/contraception mhealth intervention targeting high-risk female
students at the University of Zambia. The peer-navigator intervention will be facilitated by a tablet-based platform
to assess HIV and unintended pregnancy risk, provide education and information, link high-risk young women to
sexual and reproductive services, assess preferences for peer support, track the use of health services, and
provide ongoing support for PrEP and contraception uptake and persistence through regular communication.
Using a mixed methods phased approach guided by integrated behavioral and mHealth theories, we will first
adapt an existing app (PEBRA) using Human-Centered Design and qualitative methods to create a new tablet-
based app to serve as a platform for peer navigators to promote and track PrEP and contraception use among
high-risk female students (Aim 1, R21 phase). After several iterations have been evaluated by stakeholders, we
will test the app and peer-navigator intervention package in a small prospective single-arm trial, collecting data
on the functionality of the app and the acceptably/appropriateness of the peer-navigator intervention (Aim 2, R21
phase). After refining the app and intervention package, we will then thoroughly test the mHealth intervention
through a single-site hybrid type 1 effectiveness-implementation randomized controlled trial to 1) determine the
effectiveness of the intervention to increase PrEP use and modern contraceptive use, 2) establish underlying
behavioral mechanisms, and 3) evaluate implementation-related factors that will enhance the likelihood for the
mHealth intervention to be implemented, sustained, and scaled (Aim 3, R33 phase). If proven effective, the peer-
navigator mHealth intervention will provide a scalable model to fill-in persistent gaps in HIV prevention and
reproductive health among young women in high HIV prevalence low- and middle-income country settings.
项目摘要/摘要
艾滋病毒感染和意外怀孕在青春期女孩和
低收入和中等收入国家的年轻妇女。由于许多生物、社会和结构因素,
撒哈拉以南非洲的少女和年轻妇女仍然是最容易感染艾滋病毒的亚群。
感染。此外,青春期女孩和年轻妇女中的大多数怀孕发生在低收入和低收入家庭。
撒哈拉以南非洲的中等收入国家的这一比例最高。在赞比亚,女子大学
学生是被忽视的、艾滋病毒感染和意外怀孕的高危亚人群。口述前-
暴露预防(PrEP)和现代避孕是关键的生物医学预防工具,但增加了
事实证明,撒哈拉以南非洲的年轻女性对这一问题的了解具有挑战性。根据初步研究,我们
建议设计一种针对高危女性的新型同伴导航器PrEP/避孕mHealth干预
赞比亚大学的学生。同行导航员的干预将由基于平板电脑的平台提供便利
评估艾滋病毒和意外怀孕风险,提供教育和信息,将高危年轻妇女与
性服务和生殖服务,评估同伴支持的偏好,跟踪保健服务的使用情况,以及
通过定期沟通,持续支持PrEP和避孕的摄取和坚持。
在整合的行为理论和移动健康理论的指导下,使用混合方法分阶段方法,我们将首先
使用以人为本的设计和定性方法调整现有应用程序(PEBRA),以创建新的平板电脑-
基于APP的应用程序,作为同行导航员的平台,在
高危女生(目标1,R21阶段)。经过利益相关者的多次评估后,我们
将在一项小型前瞻性单臂试验中测试应用程序和同行导航员干预包,收集数据
关于应用程序的功能和同行导航员干预的可接受性/适当性(目标2,R21
阶段)。在细化应用程序和干预包之后,我们将彻底测试mHealth干预
通过单点混合1型有效性-实施随机对照试验1)确定
增加PrEP使用率和现代避孕药具使用率的干预措施的有效性,2)建立
行为机制,以及3)评估与实施相关的因素,这些因素将增加
要实施、持续和扩大的移动健康干预(目标3,R33阶段)。如果证明有效,同龄人-
Navigator mHealth干预将提供一个可扩展的模式,以填补艾滋病毒预防和治疗方面的长期空白
艾滋病毒高流行率、低收入和中等收入国家的年轻妇女的生殖健康。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Karen Marie Hampanda其他文献
Karen Marie Hampanda的其他文献
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{{ truncateString('Karen Marie Hampanda', 18)}}的其他基金
mHealth Intervention to Increase Uptake of Contraception and PrEP Among Female University Students in Zambia
移动医疗干预措施提高赞比亚女大学生对避孕和 PrEP 的采用率
- 批准号:
10536340 - 财政年份:2022
- 资助金额:
$ 17.95万 - 项目类别:
Promoting HIV health behaviors among pregnant couples in Zambia using an adaptive relationship strengthening intervention
使用适应性关系强化干预措施促进赞比亚怀孕夫妇的艾滋病毒健康行为
- 批准号:
10159962 - 财政年份:2018
- 资助金额:
$ 17.95万 - 项目类别:
Promoting HIV health behaviors among pregnant couples in Zambia using an adaptive relationship strengthening intervention
使用适应性关系强化干预措施促进赞比亚怀孕夫妇的艾滋病毒健康行为
- 批准号:
10398907 - 财政年份:2018
- 资助金额:
$ 17.95万 - 项目类别:
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