Translational Physician-Scientist Training Program in Oncology

描述(由申请人提供)：埃默里大学血液学和内科肿瘤学系(HMO)和Winship癌症研究所提出了一项肿瘤学T32翻译医生-科学家培训计划。这一为期2.5年的培训计划(包括由卫生与公众服务部内部资助的6个月，以及2年的T32资助)将使血液学/肿瘤学研究员能够在基础/翻译研究方法方面获得强有力的教育，最终目标是为每个受训人员建立一个独立的研究计划。许多研究记录了医生-科学家管道的损耗，这在很大程度上是由于在获得赠款资金方面面临的挑战。 提供高水平的指导和支持对于培育年轻内科科学家的发展并将他们留在学术机构是必要的。培训计划的目的是(1)提供足够大的导师库，以便为每个受训人员选择最合适的研究课题(S)；(2)通过与不同专业的基础和临床研究人员的互动，促进癌症护理和以患者为中心的多学科研究方法； (3)在研究设计、方法和分析方面提供指导，以培养翻译肿瘤学领域发展中的内科科学家的独立性，重点关注实体肿瘤，主要包括头颈、肺、乳房、胃肠道和泌尿生殖系统恶性肿瘤；以及(4)指导受训人员制定和提交他们的第一份拨款申请(S)。培训计划将每年招聘2名住院医生，具有2-3年的内科临床培训经验，强烈希望发展基础科学研究技能 肿瘤学，以及对学术医学的承诺。所有受训人员最初将被招募到现有的血液学/肿瘤学奖学金计划，并将首先完成为期18个月的PGY-4和PGY-5前半期奖学金的临床要求(以满足ACGME的董事会资格要求)。学员随后将进行为期2.5年的T32培训计划研究，从PGY-5下半年到PGY-7，这将包括在研究设计、方法和分析方面的密切指导，在职业发展和赠款准备方面的支持，以及参与严格定义的培训课程。培训将侧重于对成功的学术生涯至关重要的要素，特别是在会议报告、手稿出版物和申请独立研究资金方面取得的进展。通过对拟议的肿瘤学翻译医生-科学家培训计划的坚定承诺，Emory HMO部门和Winship打算积极为培训和指导下一代医生-科学家肿瘤学家做出贡献，支持他们在学术研究生涯的早期阶段。

DESCRIPTION (provided by applicant): The Department of Hematology and Medical Oncology (HMO) and the Winship Cancer Institute at Emory University proposes a T32 Translational Physician-Scientist Training Program in Oncology. This 2.5-year Training Program (including 6 months funded internally by the HMO Department, and 2 years of T32 funding support) will enable hematology/oncology fellows to acquire a strong education in basic/translational research approaches, with the ultimate goal of establishing an independent research program for each trainee. Many studies have documented the attrition of the physician-scientist pipeline, due in large part to the challenges faced in obtaining grant funding. Providing a high level of mentoring and support is necessary to nurture the development of young physician-scientists and retain them in academic institutions. The Training Program aims to (1) provide a sufficiently large mentor pool from which to select the most appropriate research topic(s) for each trainee; (2) foster a multidisciplinary approach to cancer care and patient-oriented research through interaction with basic and clinical investigators of diverse specialties; (3) provide guidance in research design, methodology and analysis that will foster the independence of developing physician-scientists in the field of translational oncology, focused on solid tumors mainly including head and neck, lung, breast, gastrointestinal and genitourinary malignancies; and (4) guide trainees through the development and submission of their first grant application(s). The Training Program will recruit 2 residents per year with 2-3 years of prior clinical training in internal medicine, a strong desire to develop basic science research skills in oncology, and a commitment to academic medicine. All trainees will initially be recruited to the existing Hematology/Oncology Fellowship Program, and will first complete 18 months of clinical requirements for the fellowship in PGY-4 and the first half of PGY-5 (to fulfill the board eligibilty requirements of the ACGME). Trainees will then undertake 2.5 years of T32 Training Program research, from the second half of PGY-5 through PGY-7, which will encompass close mentoring in research design, methodology and analysis, support in career development and grant preparation, and participation in a rigorously defined training curriculum. Training will focus on elements critical for a successful academic career, particularly progress towards conference presentations, manuscript publications, and applications for independent research funding. Through its strong commitment to the proposed Translational Physician-Scientist Training Program in Oncology, the Emory HMO Department and the Winship intend to actively contribute to training and mentoring the next generation of physician-scientist oncologists, supporting them in the early steps of their academic research careers.