Social Cognition in Latinx Individuals with Schizophrenia

拉丁裔精神分裂症患者的社会认知

• 批准号: 10677960
• 负责人: Ana Teresa Flores
• 金额: $ 4.38万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-03-02 至 2025-03-01
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10677960
• 关键词: Acculturation; Activities of Daily Living; Address; Affect; Age; Area; Asian; Attention; Black race; Characteristics; Clinical Trials; Cognition; Cognitive; Cognitive deficits; Communities; Competence; Data; Data Analyses; Data Set; Development; Diagnosis; Disparity; Education; Emotional; Emotions; Ensure; Equity; Ethnic Origin; Evaluation; Evaluation Studies; Evidence based treatment; Gender; Goals; Hispanic Populations; Impairment; Individual; Intervention; Interview; Language; Language Development; Latinx; Latinx population; Measurement; Measures; Mental Health; Mental Health Services; Methodology; Methods; Mind; Modeling; National Institute of Mental Health; Neurocognition; Outcome; Participant; Pattern; Perception; Population; Process; Production; Property; Psychometrics; Race; Recovery of Function; Research; Research Methodology; Research Personnel; Research Training; Risk; Sampling; Schizophrenia; Science; Service delivery model; Services; Social support; Socioeconomic Status; Source; Strategic Planning; Subgroup; Task Performances; Testing; Treatment Effectiveness; Underrepresented Populations; Underserved Population; Validation; Variant; Work; cognitive interview; cognitive process; cognitive rehabilitation; cognitive task; community engaged research; ethnic minority; experience; family support; functional improvement; functional outcomes; health care disparity; improved; innovation; investigator training; peer; preference; psychosocial; rapid growth; recruit; response; schizophrenia spectrum disorder; social; social cognition; social culture; social influence; social skills; sociocultural determinant; standard measure; symptomatology; theories

7. PROJECT SUMMARY Individuals with a schizophrenia spectrum disorder who identify as an ethnic minority are at greater risk of experiencing mental health care disparities, attributed in part to a lack of fit between treatment approaches and cultural preferences. Given the rapid growth of Latinxs in the U.S., estimated to account for 29% of the population by 2050, attention to cross-cultural research with Latinxs is essential for equitable schizophrenia treatment delivery to this underrepresented and underserved population. For instance, social cognition has emerged as an important treatment target for functional recovery in schizophrenia, but scholars have called attention to the predominately Western understanding of social cognition and point to concerns about the cross-cultural validity of social-cognitive tasks used in clinical trials. With a focus on social cognition, the current project proposes a research training plan that facilitates the applicant’s development into an independent researcher addressing disparities in mental health outcomes for Latinxs living with schizophrenia by (1) gaining expertise in psychometric analyses with a focus on cross- cultural validation that ensures fair assessment during clinical trials, (2) implementing best practices for research with Latinxs living with schizophrenia, and (3) conducting community-engaged research methodology that allows for the involvement of service users in the development of culturally-appropriate interventions. The complementary research plan aims to generate a better understanding of how the measurement and construct of social cognition might differ between Latinx individuals living with schizophrenia and their white peers. The specific aims are to (1) evaluate the psychometric properties of field-standard measures of social cognition in a secondary data set of Latinxs with schizophrenia (n = 71); (2) to investigate the functional significance of social-cognitive treatment targets in this same sample, as well as the potential influence of acculturation; and (3) conduct and analyze culturally-focused cognitive interviews (n = 30) to identify potential cultural bias within the measures. Previous research has shown that cognitive interviews are effective for elucidating sociocultural factors that influence the item-response process and go beyond quantitative methods by providing an opportunity to identify the source, rather than just the presence, of measurement disparities. The implications for such information include the development of culturally-relevant psychosocial interventions that target social-cognitive deficits in Latinxs living with schizophrenia, in line with NIMH’s Strategic Plan (Goal 4, Objective 4.3). Innovative service delivery models for the Latinx population living with schizophrenia can assist with improved acceptability, access, and effectiveness of treatment.

7. 项目概要 患有精神分裂症谱系障碍且属于少数族裔的个体面临更大的风险 经历精神卫生保健差异，部分原因是治疗方法和治疗方法之间缺乏契合 文化偏好。鉴于拉丁裔在美国的快速增长，估计占总人口的 29% 到 2050 年，关注拉丁裔的跨文化研究对于公平精神分裂症至关重要 向这一代表性不足且服务不足的人群提供治疗。例如，社会认知 已成为精神分裂症功能恢复的重要治疗目标，但学者们称 关注主要是西方对社会认知的理解，并指出对 临床试验中使用的社会认知任务的跨文化有效性。 当前项目以社会认知为重点，提出了一项研究培训计划，以促进 申请人发展成为一名独立研究人员，解决心理健康结果的差异 患有精神分裂症的拉丁裔通过 (1) 获得心理测量分析方面的专业知识，重点是跨学科分析 确保临床试验期间公平评估的文化验证，(2) 实施最佳实践 对拉丁裔精神分裂症患者进行研究，以及（3）开展社区参与的研究方法 这使得服务使用者能够参与制定适合文化的干预措施。 补充研究计划旨在更好地了解如何测量和 拉丁裔精神分裂症患者和白人患者的社会认知结构可能有所不同 同行。具体目标是（1）评估社会领域标准测量的心理测量特性 患有精神分裂症的拉丁裔的二级数据集中的认知能力（n = 71）； (2) 功能性研究 同一样本中社会认知治疗目标的重要性，以及潜在影响 文化适应； (3) 进行和分析以文化为中心的认知访谈 (n = 30)，以识别潜在的 措施中的文化偏见。先前的研究表明认知访谈对于 阐明影响项目反应过程并超越定量方法的社会文化因素 通过提供一个机会来识别测量差异的来源，而不仅仅是其存在。 这些信息的影响包括制定与文化相关的社会心理干预措施 根据 NIMH 的战略计划（目标），针对拉丁裔精神分裂症患者的社会认知缺陷 4，目标 4.3）。为拉丁裔精神分裂症患者提供创新的服务提供模式 协助提高治疗的可接受性、可及性和有效性。