NICHD HUMAN BIOSPECIMEN REPOSITORY – MPIDB PHACS HOPE SPECIMEN

母婴传染病分支（MPIDB）促进研究，以调查艾滋病毒及其并发症的影响和治疗，以及婴儿，儿童，青少年，孕妇和非孕妇的其他重大传染病。这包括主要在两个主要网络中开展的合同临床研究活动，这些网络积极收集标本，存放在NICHD储存库中。这就是儿科艾滋病队列研究（PHACS）。 PHACS是一个多中心的美国为基础的计划，以下围产期艾滋病毒感染的青年和艾滋病毒暴露/未感染的婴儿，儿童和青年。PHACS目前包括四个主要方案和四个子研究。在18个SMARTT（艾滋病毒感染妇女所生未感染艾滋病毒儿童的ART毒性研究监测）和14个AMP（青少年主方案）当前需要储存服务的研究中心收集了各种标本类型。 围绕怀孕和接触艾滋病毒/抗逆转录病毒药物的健康结果（希望）探讨了生殖健康选择，包括怀孕，以及总体健康结果，包括生殖健康结果。HOPE为感染艾滋病毒的妇女及其家庭提供了了解未来进展的机会。

The Maternal and Pediatric Infectious Disease Branch (MPIDB) promotes research to investigate the impact and treatment of HIV, its complications, and other significant infectious diseases in infants, children, adolescents, and pregnant and nonpregnant women. This includes contracted clinical research activities conducted primarily in two major networks that actively collect specimens to be housed in the NICHD repository. These are the Pediatric HIV AIDS Cohort Study (PHACS). PHACS is a multicenter United States-based program that follows both perinatally HIV-infected youth and HIV-exposed/uninfected infants, children, and youth. PHACS currently includes four main protocols and four sub studies. A wide variety of specimen types are collected at 18 SMARTT (Surveillance Monitoring for ART Toxicities Study in HIV-uninfected Children Born to HIV-infected Women) and 14 AMP (Adolescent Master Protocol) current study sites that require repository services. The Health Outcomes around Pregnancy and Exposure to HIV/ARVs (HOPE) explores reproductive health choices, including pregnancy, and overall health outcomes, including reproductive health outcomes. HOPE provides the opportunity to inform future advancements for women living with HIV and their families.