LOTUS: An mHealth Intervention to Improve HIV Prevention Service Engagement and Intersectional Stigma among Racially Diverse Women Who Use Drugs

LOTUS：一项移动医疗干预措施，旨在提高艾滋病毒预防服务的参与度，并消除吸毒的不同种族女性之间的交叉耻辱

• 批准号: 10678886
• 负责人: Stephanie Alice Meyers-Pantele
• 金额: $ 18.02万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-08-15 至 2027-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10678886
• 关键词: AIDS prevention; Address; Adherence; Adopted; Adoption; Affect; African American; Awareness; Behavior Therapy; Biological; Black race; California; Characteristics; Clinic; Communicable Diseases; Communities; Consolidated Framework for Implementation Research; Coping Skills; County; Data; Development; Discrimination; Drug usage; Drug user; Educational workshop; Eligibility Determination; Employee; Environment; Epidemic; Feedback; Fostering; Future; Gender; Goals; HIV; HIV Infections; HIV Seronegativity; HIV disparities; HIV/STD; Health; Health behavior; Hybrids; Incidence; Individual; Instruction; Intervention; Interview; Knowledge; Latina; Link; Measures; Medical; Mentored Research Scientist Development Award; Mentors; Methods; Morality; Participant; Patient Self-Report; Population; Positioning Attribute; Prevention Research; Procedures; Process; Productivity; Provider; Public Health; Qualitative Methods; Race; Randomized; Randomized, Controlled Trials; Research; Risk; Scientist; Services; Social support; Stimulant; Suggestion; Testing; Training; United States Dept. of Health and Human Services; Universities; Violence; Woman; base; career; cis-female; community organizations; design; ethnic diversity; experience; hands on research; health care availability; health care service; health equity; implementation science; improved; informant; intersectionality; mHealth; member; men; motherhood; novel; opioid use; pre-exposure prophylaxis; prevention service; racial diversity; secondary analysis; service engagement; skill acquisition; skills; social norm; social stigma; substance use; theories; therapy design; therapy development; transmission process; uptake; usability; user centered design

PROJECT SUMMARY/ABSTRACT Candidate. Dr. Meyers-Pantele applies for this K01 mentored training award with the independent career goal of attaining a productive and independent research career as a health behavior interventionist focused on reducing HIV disparities among women who use drugs (WWUD). Her current training, however, does not extend beyond the secondary analysis of stigma, and substance use data, and is insufficient for in-depth instruction on the theoretical and practical methods required for the development and implementation of health behavior interventions for racially and ethnically diverse WWUD. Specifically, the K01 training will support her transition to an independent career scientist by: (1) developing proficiency in intersectionality theory to inform an intervention targeting HIV prevention service engagement and intersectional stigma for racially diverse WWUD, (2) gaining expertise in mHealth intervention design and development to create the proposed mHealth intervention, (3) building proficiency in the implementation of randomized controlled trials to pilot the developed intervention, (4) strengthening her skill base in implementation science to design an intervention that has the potential for adoption and implementation, and (5) fostering the personal development skills necessary for a successful academic career. These training aims will be accomplished through didactic courses, training workshops, participation in professional research networks, hands-on research, and mentored training. Research and Environment. WWUD are at increased risk for HIV and have low levels of pre-exposure prophylaxis knowledge and acceptance. Additionally, racially and ethnically diverse WWUD experience intersectional stigma due to gendered and racialized social norms surrounding womanhood, motherhood, morality, substance use, and criminality, all of which have important implications for women’s engagement with HIV prevention services. Mobile health (mHealth) interventions and interventions that target intersectional stigma have the potential to increase HIV prevention service engagement, but there is a dearth of interventions tailored toward racially diverse WWUD. The proposed research will provide Dr. Meyers-Pantele with the training to address this critical gap in HIV prevention research. She will employ qualitative methods to identify key experiences with HIV prevention services and intersectional stigma, and potential barriers and facilitators to intervention adoption and implementation, to inform the development of potential theory-driven mHealth intervention components. This information will be used to develop and test the usability of the mheaLth interventiOn To redUce Stigma (LOTUS) intervention to improve HIV prevention service engagement and intersectional stigma for racially and ethnically diverse WWUD. Lastly, she will conduct a pilot RCT to assess the feasibility, acceptability, and preliminary impact of the LOTUS intervention. This training will uniquely position her as one of few mHealth interventionists specializing in intersectional stigma for WWUD at UCSD.

项目总结/摘要 候选人Meyers-Pantele博士以独立的职业目标申请K 01指导培训奖 作为一名健康行为干预者， 减少吸毒妇女在艾滋病毒方面的差距（世界妇女发展联盟）。然而，她目前的训练并没有 超出了对耻辱和物质使用数据的二级分析，不足以进行深入研究。 关于发展和实施卫生保健所需的理论和实践方法的指导 行为干预种族和民族多样化的WWUD。具体来说，K 01培训将支持她 过渡到一个独立的职业科学家：（1）发展交叉性理论的熟练程度，以告知 针对艾滋病毒预防服务参与和种族多样性交叉污名的干预措施 WWUD，（2）获得移动健康干预设计和开发方面的专业知识，以创建拟议的移动健康 干预，（3）建设熟练的随机对照试验的实施，以试点发达国家 干预，（4）加强她在实施科学方面的技能基础，以设计一种具有 潜在的采用和实施，以及（5）培养个人发展所需的技能， 成功的学术生涯。这些培训目标将通过教学课程、培训、 讲习班、参与专业研究网络、实践研究和指导培训。 研究与环境。WWUD感染艾滋病毒的风险增加，并且暴露前水平较低 预防知识和接受度。此外，种族和民族多样化的WWUD经验 由于围绕妇女、母亲、 道德，物质使用和犯罪，所有这些都对妇女参与 艾滋病毒预防服务。移动的保健干预措施和针对跨部门的干预措施 污名化有可能增加艾滋病毒预防服务的参与，但缺乏干预措施 为种族多样的WWUD量身定制。拟议的研究将为Meyers-Pantele博士提供 培训，以解决艾滋病毒预防研究中的这一关键差距。她将采用定性方法来确定 艾滋病毒预防服务和交叉污名的主要经验，以及潜在的障碍和促进因素 干预措施的采用和实施，为潜在的理论驱动的移动健康的发展提供信息 干预措施。这些信息将用于开发和测试医疗器械的可用性 减少羞辱（LOTUS）干预措施，以改善艾滋病毒预防服务的参与， 种族和民族多样性的WWUD的交叉耻辱。最后，她将进行一项试点RCT， LOTUS干预的可行性、可接受性和初步影响。此次培训将以独特的方式 将她定位为UCSD少数几个专门研究WWUD交叉污名的移动健康干预者之一。