2023 Mammary Gland Biology Gordon Research Conference and Gordon Research Seminar

项目摘要 戈登乳腺生物学研究会议（GRC MGB）和非常成功的戈登 研究研讨会（GRS），伴随着这次会议是独特的基础生物学和乳腺癌 会议，因为他们汇集了不同的科学家和临床科学家感兴趣的分子 以及控制正常乳腺发育、泌乳生理学、肿瘤发生 以及进展和转移。有一个强烈的关注正常和乳腺癌的基本机制 生物学和治疗（基于阐明导致乳腺癌发病的早期和晚期事件， 发展）和与该领域相关的新兴“尖端”科学。GRC MGB/GRS是唯一 会议的重点是利用正常乳腺生物学和生理学的见解， 引起乳腺癌的事件，并已成为乳腺生物学家和癌症“必须参加” 研究人员（特别是在基础和转化研究领域）在世界各地。2023年的具体目标 GRC/GRS将提供一个解决该领域关键科学问题和争议的计划。的 2023年会议将重点关注乳腺生物学领域的最新发现和突出问题 这对乳腺癌的预防和治疗以及人类健康都具有直接和长期的意义。 哺乳和婴儿健康。已确认国际专家将讨论以下主题：（1）表型 和遗传学方法来进行个性化治疗。(2)映射正常和患病状态。(3)营养素 以及正常和癌症的代谢调节。(4)激素和正常生物学的系统调节， 癌(5)正常生物学和疾病中的微生物组和炎症。(6)微环境调控 发育功能和癌症(7)正常生物学和癌症中的免疫调节。(8)表观遗传学和 可塑性在正常生物学和癌症。(9)生活方式和遗传因素与乳腺癌病因。

Project SUMMARY The Gordon Research Conference on Mammary Gland Biology (GRC MGB) and the highly successful Gordon Research Seminar (GRS) that accompanies this meeting are unique amongst basic biology and breast cancer conferences as they bring together a diverse mix of scientists and clinician-scientists interested in the molecular and cellular mechanisms that govern normal mammary gland development, lactation physiology, tumor initiation, and progression and metastasis. There is a strong focus on basic mechanisms of normal and breast cancer biology and treatment (based on elucidating the early and later events that contribute to breast cancer onset and progression) and emerging `cutting edge' science relevant to the field. The GRC MGB/GRS is the only conference focused on harnessing insights from normal mammary gland biology and physiology to understand events that give rise to breast cancer and has become a `must attend' for mammary gland biologists and cancer researchers (particularly in basic and translational research areas) the world over. The Specific Aims of the 2023 GRC/GRS are to deliver a program that addresses critical scientific questions and controversies in the field. The 2023 conference will focus on recent discoveries and outstanding questions in the mammary gland biology field that have immediate and long-term relevance to breast cancer prevention and treatment as well as human lactation and infant health. International experts have been confirmed to address the topics of (1) Phenotypic and genetic approaches for personalization of treatment. (2) Mapping normal and diseased states. (3) Nutrients and metabolism regulation of normal and cancer. (4) Hormones and systemic regulation of normal biology and cancer. (5) Microbiome and inflammation in normal biology and disease. (6) Microenvironment modulation of development, function, and cancer. (7) Immune modulation in normal biology and cancer. (8) Epigenetics and plasticity during normal biology and cancer. (9) Lifestyle and genetic factors and breast cancer etiology.