2023 Mammary Gland Biology Gordon Research Conference and Gordon Research Seminar

项目总结

Project SUMMARY The Gordon Research Conference on Mammary Gland Biology (GRC MGB) and the highly successful Gordon Research Seminar (GRS) that accompanies this meeting are unique amongst basic biology and breast cancer conferences as they bring together a diverse mix of scientists and clinician-scientists interested in the molecular and cellular mechanisms that govern normal mammary gland development, lactation physiology, tumor initiation, and progression and metastasis. There is a strong focus on basic mechanisms of normal and breast cancer biology and treatment (based on elucidating the early and later events that contribute to breast cancer onset and progression) and emerging `cutting edge' science relevant to the field. The GRC MGB/GRS is the only conference focused on harnessing insights from normal mammary gland biology and physiology to understand events that give rise to breast cancer and has become a `must attend' for mammary gland biologists and cancer researchers (particularly in basic and translational research areas) the world over. The Specific Aims of the 2023 GRC/GRS are to deliver a program that addresses critical scientific questions and controversies in the field. The 2023 conference will focus on recent discoveries and outstanding questions in the mammary gland biology field that have immediate and long-term relevance to breast cancer prevention and treatment as well as human lactation and infant health. International experts have been confirmed to address the topics of (1) Phenotypic and genetic approaches for personalization of treatment. (2) Mapping normal and diseased states. (3) Nutrients and metabolism regulation of normal and cancer. (4) Hormones and systemic regulation of normal biology and cancer. (5) Microbiome and inflammation in normal biology and disease. (6) Microenvironment modulation of development, function, and cancer. (7) Immune modulation in normal biology and cancer. (8) Epigenetics and plasticity during normal biology and cancer. (9) Lifestyle and genetic factors and breast cancer etiology.