Center Administration Core
中心行政核心
基本信息
- 批准号:10688113
- 负责人:
- 金额:$ 33.32万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2021
- 资助国家:美国
- 起止时间:2021-09-23 至 2026-08-31
- 项目状态:未结题
- 来源:
- 关键词:AdministratorAdvisory CommitteesAnnual ReportsCalendarCellsCollaborationsCommunicationCommunitiesCore FacilityDataExpenditureFundingFutureGoalsInstitutionLeadershipLinkLogisticsMemorial Sloan-Kettering Cancer CenterMouse Cell LineNeoplasm MetastasisOccupational activity of managing financesOffice of Administrative ManagementOrganization administrative structuresPathologistPhysiciansPilot ProjectsPreparationProgress ReportsProtocols documentationPublicationsReagentReportingResearchResearch PersonnelResearch Project GrantsResource AllocationResourcesScheduleScientistStructureSystemUnited States National Institutes of HealthUniversitiesUpdatecareer developmentmeetingsoutreachsingle cell sequencingtumorweb site
项目摘要
Summary
The Administrative Core A will serve as the organizing core of the Center for Systems-level Study of
Metastasis. Administrative Core A will be located at Rockefeller University and will manage the administrative,
financial and programmatic aspects of the Projects and Cores of the Center. It will also coordinate sharing of
research findings and resources amongst the investigators of the Center and will communicate to the broader
NCI MetNet centers, NCI leadership and will provide outreach to the broader community of NCI metastasis
centers. The structure of Administrative Core A will consist of an Executive Board, an External Advisory
Committee, a Center Administrator and a Center Data manager.
The first aim of Administrative Core A is to manage the logistics and communication for the Center by
i) facilitating internal communications between the investigators of the 3 projects and the Single-Cell
Sequencing and Computational Core,
ii) enhancing external communications with NCI staff and MetNet centers,
iii) preparing documents for Center activities, including annual reports for the NIH and the External
Advisory Committee and iv) enhancing communications with collaborating scientists and physician-
scientists at other institutions.
The second aim of Administrative Core A is to coordinate activities within the Center and with other MetNet
centers by
i) scheduling and coordinating weekly meetings, where each project will be discussed monthly,
ii) scheduling and coordinating quarterly meetings of the Executive Committee,
iii) organizing annual meetings of the Center and External Advisory Committee and
iv) establishing an internal web site for communications amongst Center investigators and an external
website for reporting on publications, goals of the Center and protocol for requesting reagents.
The third aim of the Administrative Core A is to track and evaluate the progress of the Center by
i) assessing progress of the three Projects and that of the Single-cell Sequencing and Computational
Core and Intra-Center Pilot Projects,
ii) tracking long-term needs of the Projects,
iii) preparing updates on progress relative to 12-month milestones for each project and
iv) facilitating the career development of junior investigators.
概括
行政核心A将作为系统级研究中心的组织核心
转移。行政核心 A 将位于洛克菲勒大学,负责管理行政、
该中心的项目和核心的财务和计划方面。它还将协调共享
中心研究人员的研究成果和资源,并将传达给更广泛的人
NCI MetNet 中心、NCI 领导层并将向更广泛的 NCI 转移社区提供外展服务
中心。行政核心 A 的结构将由执行委员会、外部顾问组成
委员会、中心管理员和中心数据经理。
行政核心 A 的首要目标是通过以下方式管理中心的后勤和通讯:
i) 促进 3 个项目的研究人员与 Single-Cell 之间的内部沟通
测序和计算核心,
ii) 加强与 NCI 工作人员和 MetNet 中心的外部沟通,
iii) 为中心活动准备文件,包括向 NIH 和外部机构提交的年度报告
咨询委员会和 iv) 加强与合作科学家和医生的沟通-
其他机构的科学家。
行政核心 A 的第二个目标是协调中心内部以及与其他 MetNet 的活动
中心由
i) 安排和协调每周会议,每月讨论每个项目,
ii) 安排和协调执行委员会的季度会议,
iii) 组织中心和外部咨询委员会的年度会议以及
iv) 建立一个内部网站,以便中心调查人员和外部人员之间进行交流
用于报告出版物、中心目标和试剂请求协议的网站。
行政核心 A 的第三个目标是通过以下方式跟踪和评估中心的进展:
i) 评估三个项目以及单细胞测序和计算项目的进展
核心和中心内试点项目,
ii) 跟踪项目的长期需求,
iii) 准备每个项目 12 个月里程碑相关的进展更新,以及
iv) 促进初级研究者的职业发展。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Sohail F. Tavazoie其他文献
A commonly inherited human emPCSK9/em germline variant drives breast cancer metastasis via LRP1 receptor
一种常见的遗传性人类前蛋白转化酶枯草杆菌蛋白酶/kexin 型 9(PCSK9)种系变体通过低密度脂蛋白受体相关蛋白 1(LRP1)受体驱动乳腺癌转移
- DOI:
10.1016/j.cell.2024.11.009 - 发表时间:
2025-01-23 - 期刊:
- 影响因子:42.500
- 作者:
Wenbin Mei;Schayan Faraj Tabrizi;Christopher Godina;Anthea F. Lovisa;Karolin Isaksson;Helena Jernström;Sohail F. Tavazoie - 通讯作者:
Sohail F. Tavazoie
Neuronal substance P drives metastasis through an extracellular RNA–TLR7 axis
神经元 P 物质通过细胞外 RNA-TLR7 轴驱动转移
- DOI:
10.1038/s41586-024-07767-5 - 发表时间:
2024-08-07 - 期刊:
- 影响因子:48.500
- 作者:
Veena Padmanaban;Isabel Keller;Ethan S. Seltzer;Benjamin N. Ostendorf;Zachary Kerner;Sohail F. Tavazoie - 通讯作者:
Sohail F. Tavazoie
Endothelial-cell killing promotes metastasis
内皮细胞杀伤促进转移
- DOI:
10.1038/nature19465 - 发表时间:
2016-08-03 - 期刊:
- 影响因子:48.500
- 作者:
Claudio R. Alarcón;Sohail F. Tavazoie - 通讯作者:
Sohail F. Tavazoie
Transfer RNAs as dynamic and critical regulators of cancer progression
转运 RNA 作为癌症进展的动态且关键的调节因子
- DOI:
10.1038/s41568-023-00611-4 - 发表时间:
2023-10-09 - 期刊:
- 影响因子:66.800
- 作者:
Alexandra M. Pinzaru;Sohail F. Tavazoie - 通讯作者:
Sohail F. Tavazoie
Conserved genetic basis for microbial colonization of the gut
肠道微生物定殖的保守遗传基础
- DOI:
10.1016/j.cell.2025.03.010 - 发表时间:
2025-05-01 - 期刊:
- 影响因子:42.500
- 作者:
Menghan Liu;Sydney B. Blattman;Mai Takahashi;Nandan Mandayam;Wenyan Jiang;Panos Oikonomou;Sohail F. Tavazoie;Saeed Tavazoie - 通讯作者:
Saeed Tavazoie
Sohail F. Tavazoie的其他文献
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{{ truncateString('Sohail F. Tavazoie', 18)}}的其他基金
Project-1: Defining the mechanisms by which neurons promote breast cancer metastasis
项目 1:定义神经元促进乳腺癌转移的机制
- 批准号:
10493338 - 财政年份:2021
- 资助金额:
$ 33.32万 - 项目类别:
Project-1: Defining the mechanisms by which neurons promote breast cancer metastasis
项目-1:定义神经元促进乳腺癌转移的机制
- 批准号:
10688115 - 财政年份:2021
- 资助金额:
$ 33.32万 - 项目类别:
Project-1: Defining the mechanisms by which neurons promote breast cancer metastasis
项目 1:定义神经元促进乳腺癌转移的机制
- 批准号:
10271737 - 财政年份:2021
- 资助金额:
$ 33.32万 - 项目类别:
Regulation of metastatic progression by an endothelial-derived factor
内皮衍生因子对转移进展的调节
- 批准号:
10155448 - 财政年份:2019
- 资助金额:
$ 33.32万 - 项目类别:
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