Administrative Core

行政核心

• 批准号: 10704046
• 负责人: JEFFREY R. CURTIS
• 金额: $ 26.64万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-15 至 2024-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10704046
• 关键词: Address; Advisory Committees; Alabama; Area; Arthritis; Autoimmunity; Bioinformatics; Biometry; Biosensor; Center for Translational Science Activities; Clinical; Clinical Research; Clinical Sciences; Collection; Communities; Core Facility; Data; Data Sources; Dermatology; Development; Devices; Disease; Doctor of Philosophy; Education; Electronic Health Record; Ensure; Environment; Epidemiology; Evaluation; Evolution; Faculty; Fostering; Funding; Future; Goals; Gout; Grant; Health Technology; Health care facility; Healthcare; Hyperuricemia; Individual; Informatics; Institution; Investigation; Knowledge; Leadership; Machine Learning; Methodology; Methods; Mission; Musculoskeletal; Musculoskeletal Diseases; National Center for Advancing Translational Sciences; National Institute of Arthritis, and Musculoskeletal, and Skin Diseases; Natural Language Processing; Orthopedics; Outcomes Research; Patient Care; Patient Outcomes Assessments; Patients; Pharmaceutical Economics; Pharmacoepidemiology; Policy Maker; Registries; Research; Research Personnel; Research Project Grants; Resources; Rheumatism; Rheumatology; Science; Services; Technology; Translational Research; Universities; Visualization; Work; base; bone; catalyst; clinical center; comorbidity; computer science; computerized data processing; data visualization; deep learning; design; digital health; digital imaging; early-career faculty; effectiveness research; experience; health plan; implementation science; improved; innovation; knowledge translation; member; mobile application; mobile computing; new technology; novel; operation; programs; research study; skills; skin disorder; smartphone application; statistics; tool; wearable device; wearable sensor technology

PROJECT SUMMARY The University of Alabama at Birmingham's (UAB) Building and InnovatinG: Digital heAlth Technology and Analytics (BIGDATA) Core Center will serve as a catalyst for the design and implementation of rigorous, high- impact clinical research studies advance musculoskeletal, arthritis and skin disease research inside and outside the confines of traditional health care facilities, using data captured by mobile technology including Smartphone Apps and wearable biosensor devices. Oversight of the Center will be provided by the Administrative Core directed by Jeffrey Curtis, MD, MS, MPH, Associate Director Huifeng Yun, PhD, and key faculty S. Louis Bridges, Jr., MD, PhD and, Kenneth Saag, MD, MSc. The central purpose of the Administrative Core is to oversee all operations of the Center and facilitate BIGDATA's mission to improve the design, collection and analysis of real-world (e.g. electronic health record, registry, health plan, biosensor), and 'omic' data as applied to rheumatologic, musculoskeletal, and skin disease research using both traditional and novel data sources (e.g. Smartphone Apps, biosensors/wearables, digital images) and methods (e.g. data visualization; natural language processing data; machine learning and deep learning analytics) via the following specific aims: (1) Set the priorities and the overall strategic agenda to facilitate rheumatologic, musculoskeletal, and skin disease research; (2) Coordinate Core facilities, supporting a vigorous intellectual and scholarly research environment; (3) Facilitate the continued evolution of the highly successful Methodologic Core and its expansion to incorporate novel technologies embedded in the Data Capture & Integration Core (DCI) to develop new services and innovative research projects using state-of-the-art tools from rheumatology, informatics, statistics, epidemiology, implementation science, and outcomes research at UAB and Auburn University; (4) Oversee the continuation of the outstanding educational enrichment programs designed to bolster the knowledge and skills of the user base, leading to higher quality clinical research; (5) Foster the development and provide oversight and management of Pilot and Feasibility projects; (6) Coordinate interactions with the Executive & Advisory Committees, and existing UAB entities such as the NCATS-funded Center for Clinical and Translational Science, UAB Informatics Institute, NIAMS-funded Investigations in Gout, Hyperuricemia, and Comorbidities P50 Center of Research Translation; the Comprehensive Arthritis, Musculoskeletal, Bone, and Autoimmunity Center; Center for Outcomes and Effectiveness Research and Education, and the UAB Pharmacoepidemiology & pharmacoEconomics unit; (7) Serve as the evaluation touchstone to: a) ensure continuous quality improvement in leadership, engagement and the quality of services and resources provided by BIGDATA to the User Base, and b) quantify BIGDATA's impact on the research community.

项目摘要 亚拉巴马大学伯明翰分校（UAB）建筑与创新：数字健康技术与 分析（BIGDATA）核心中心将作为催化剂的设计和实施严格的，高， 影响临床研究研究推进肌肉骨骼、关节炎和皮肤病研究， 在传统医疗保健设施的范围之外，使用移动的技术捕获的数据，包括 智能手机应用程序和可穿戴生物传感器设备。对中心的监督将由 管理核心由Jeffrey Curtis，MD，MS，MPH，副主任Huifeng Yun，PhD和关键 教师S.小路易斯·布里奇斯Kenneth Saag，MD，MSc.的中心目的 行政核心是监督中心的所有运作，并促进BIGDATA的使命，以改善 设计、收集和分析真实世界（例如电子健康记录、登记、健康计划、生物传感器），以及 “组学”数据应用于风湿病，肌肉骨骼和皮肤病研究，使用传统和 新颖的数据源（例如智能手机应用程序、生物传感器/可穿戴设备、数字图像）和方法（例如数据 可视化;自然语言处理数据;机器学习和深度学习分析）。 具体目标如下：（1）确定优先事项和总体战略议程，以促进风湿病学， 肌肉骨骼和皮肤疾病研究;（2）协调核心设施，支持充满活力的知识分子 （3）促进高度成功的持续发展; 方法论核心及其扩展，以纳入嵌入在数据采集和 集成核心（DCI），使用最先进的工具开发新服务和创新研究项目 从流变学，信息学，统计学，流行病学，实施科学和成果研究， UAB和奥本大学;（4）监督优秀教育充实计划的延续 旨在加强用户基础的知识和技能，从而提高临床研究的质量;（5） 促进试点项目和可行性项目的开发并提供监督和管理;（6） 协调与执行和咨询委员会以及现有UAB实体（如 临床和转化科学中心，UAB信息学研究所，NIAMS资助 痛风、高尿酸血症和合并症的研究 关节炎、肌肉骨骼、骨骼和自身免疫综合中心; 有效性研究和教育，以及UAB药物流行病学和药物经济学单位;（7） 作为评价的试金石，以：a）确保在领导、参与和 以及BIGDATA向用户群提供的服务和资源的质量，以及B）量化BIGDATA的 对研究界的影响。