A Career Development Award in Global Postpartum Health
全球产后健康职业发展奖
基本信息
- 批准号:10706338
- 负责人:
- 金额:$ 18.45万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2022
- 资助国家:美国
- 起止时间:2022-09-21 至 2027-04-30
- 项目状态:未结题
- 来源:
- 关键词:AdherenceAdministratorAdoptionAfrica South of the SaharaAfricanAgreementAreaAttentionBlood PressureCharacteristicsChildChildbirthClinical ResearchClinical TrialsClinical Trials DesignCohort StudiesCountryDataDiscipline of obstetricsEducationEligibility DeterminationEnsureEpidemiologyEquityEvaluationFamilyFogarty International CenterFoundationsFrequenciesFutureGoalsGynecologistHealthHealth Services AccessibilityHealth TechnologyHeart RateHemorrhageHomeHospitalsHourHypertensionIncomeInfantInternationalInterventionIntervention TrialInvestigationK-Series Research Career ProgramsLearningLifeMaintenanceMaternal HealthMaternal MortalityMaternal-fetal medicineMeasuresMedical RecordsMentored Research Scientist Development AwardMentorsMentorshipModelingModificationMonitorMorbidity - disease rateNorth CarolinaOutcomeOxygenParticipantPatient Monitoring SystemPatientsPhysiologic MonitoringPhysiologic pulsePhysiologicalPolicy MakerPopulationPostpartum PeriodPostpartum ProgramsPostpartum WomenPregnancyPregnant WomenPremature BirthPreventionProceduresProspective cohortProtocols documentationProviderProxyQualifyingQualitative EvaluationsRandomizedReach, Effectiveness, Adoption, Implementation, and MaintenanceRecommendationResearchResearch PersonnelResource-limited settingResourcesRiskRisk FactorsSample SizeSepsisSeriesSolidSystemTechnologyTemperatureTimeTrainingUniversitiesWomanWomen&aposs HealthZambiaadverse birth outcomesantenatalblood pressure controlcare deliverycare outcomescareercareer developmentclinical epidemiologyclinical phenotypeclinical trial implementationcohortdesigndigitaldigital healtheffectiveness/implementation trialexperiencefeasibility trialfollow-upfuture implementationglobal healthhealth applicationhigh riskhospital readmissionimplementation frameworkimplementation researchimplementation scienceimprovedimproved outcomeintrapartumlifetime riskmaternal morbiditymonitoring deviceneglectnovel strategiesobstetric outcomespost implementationpostpartum carepostpartum complicationspostpartum healthpostpartum outcomepreventprogramsrandomized trialremote monitoringrespiratorysensorsevere maternal morbidityskillsuptakewearable sensor technologywireless sensor
项目摘要
ABSTRACT
A Career Development Award in Global Postpartum Health
This application is for a Fogarty International Center K01 International Research Scientist Development Award
(IRSDA) for Dr. Bridget Spelke, MD, an obstetrician-gynecologist and research fellow in Global Women's Health
at the University of North Carolina (UNC). Dr. Spelke is in the formative stages of her research career and aims
to establish herself as an independent investigator and future leader in the area of global postpartum health, a
high-risk period that has been neglected for too long. She has lived full-time in Lusaka, Zambia since August
2019 where she has established a solid career foundation for clinical research in obstetric outcomes for women
in resource-constrained settings. Dr. Spelke's proposed K01 research will leverage a recent expansion of the
Zambian Preterm Birth Prevention Study (ZAPPS), a long-standing pregnancy cohort that is following women
and their infants through 12 months postpartum. Dr. Spelke will study a novel strategy to identify women at risk
for severe maternal morbidity and mortality in the first week after delivery: continuous remote physiologic
monitoring with easy-to-use, multiparameter, wearable sensors. To inform the design of a future hybrid
effectiveness-implementation trial, Dr. Spelke proposes a mentored research program that will estimate the
frequency of severe maternal morbidity in the ZAPPS cohort (Aim 1); implement a pilot randomized feasibility
trial of postpartum physiologic monitoring (Aim 2); and evaluate barriers and facilitators to adoption of a digital
health intervention in a resource-constrained setting through implementation research frameworks (Aim 3).
These three research aims will provide preliminary data toward the design of a future trial. They are interrelated
and independent of each other; study results will advance research on digital and postpartum health in resource-
constrained settings regardless of outcomes. Each of these studies aligns with individualized career
development goals in clinical trials design and analysis, implementation research for digital health technologies,
and collaborative global health research partnerships. Dr. Spelke has assembled a highly accomplished and
eminently qualified mentorship team comprising: her primary Zambia mentor, Prof. Bellington Vwalika, an expert
in clinical trials implementation in sub-Saharan Africa; her primary US mentor, Prof. Elizabeth Stringer, an expert
in maternal-fetal medicine and maternal health epidemiology; and her core mentor, Prof. Ben Chi, an expert in
implementation science in sub-Saharan Africa. All three mentors have decades of experience in collaborative
global health partnerships and extensive experience mentoring early career researchers. The IRSDA will
advance Dr. Spelke's skills in each of these fields, supporting both didactic and practice-based learning
opportunities, as she establishes her independent area of investigation and progresses towards research
independence in global postpartum health.
摘要
全球产后健康职业发展奖
本申请表是关于Fogarty国际中心K01国际研究科学家发展奖的申请
(IRSDA)给布里奇特·斯佩尔克博士,医学博士,产科妇科医生和全球妇女健康研究员
在北卡罗来纳大学(UNC)。斯佩尔克博士正处于她研究生涯的形成阶段,她的目标是
为了将自己确立为全球产后健康领域的独立调查者和未来的领导者,
被忽视太久的高风险期。自8月以来,她一直全职生活在赞比亚的卢萨卡
在2019年,她为妇女产科结局的临床研究奠定了坚实的职业基础
在资源受限的设置中。Spelke博士提出的K01研究将利用最近对
赞比亚早产预防研究(ZAPPS),一个长期跟踪妇女的怀孕队列
以及他们的婴儿产后12个月。斯佩尔克博士将研究一种新的策略来识别处于危险中的女性
分娩后第一周的严重孕产妇发病率和死亡率:持续远程生理学
使用易于使用的多参数可穿戴传感器进行监控。为未来混合动力车的设计提供信息
有效性-实施试验,斯皮尔克博士提出了一个有指导的研究计划,将估计
Zapps队列中产妇严重发病率的频率(目标1);实施试点随机可行性
产后生理监测试验(目标2);评估采用数字化技术的障碍和促进者
通过实施研究框架在资源有限的情况下进行卫生干预(目标3)。
这三个研究目标将为未来试验的设计提供初步数据。它们是相互关联的
并相互独立;研究成果将推进数字化和产后健康资源的研究-
受约束的设置,无论结果如何。这些研究中的每一项都与个性化的职业相一致
临床试验设计和分析、数字健康技术实施研究的发展目标,
和协作的全球卫生研究伙伴关系。斯佩尔克博士已经组装了一个非常有成就的
优秀的导师团队,成员包括:她在赞比亚的主要导师,Bellington Vwalika教授,一位专家
在撒哈拉以南非洲实施临床试验;她在美国的主要导师伊丽莎白·斯特林格教授是一名专家
母胎医学和孕产妇健康流行病学;以及她的核心导师迟本教授,他是
撒哈拉以南非洲的实施科学。这三位导师都有数十年的协作经验
全球健康伙伴关系和指导早期职业研究人员的丰富经验。IRSDA将
提高Spelke博士在这些领域的技能,支持教学和基于实践的学习
机会,因为她建立了自己的独立调查领域,并朝着研究进展
全球产后健康中的独立性。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Mae Bridget Spelke其他文献
Mae Bridget Spelke的其他文献
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{{ truncateString('Mae Bridget Spelke', 18)}}的其他基金
A Career Development Award in Global Postpartum Health
全球产后健康职业发展奖
- 批准号:
10589611 - 财政年份:2022
- 资助金额:
$ 18.45万 - 项目类别:
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